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Florian Busch
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Programmable design of orthogonal protein heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ...
Nature 565 (7737), 106-111, 2019
1802019
De novo design of protein logic gates
Z Chen, RD Kibler, A Hunt, F Busch, J Pearl, M Jia, ZL VanAernum, ...
Science 368 (6486), 78-84, 2020
1782020
De novo design of tunable, pH-driven conformational changes
SE Boyken, MA Benhaim, F Busch, M Jia, MJ Bick, H Choi, JC Klima, ...
Science 364 (6441), 658-664, 2019
1422019
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry
ZL VanAernum, F Busch, BJ Jones, M Jia, Z Chen, SE Boyken, ...
Nature protocols 15 (3), 1132-1157, 2020
1152020
Human Argonaute3 has slicer activity
MS Park, HD Phan, F Busch, SH Hinckley, JA Brackbill, VH Wysocki, ...
Nucleic acids research 45 (20), 11867-11877, 2017
1092017
Surface-induced dissociation: an effective method for characterization of protein quaternary structure
AQ Stiving, ZL VanAernum, F Busch, SR Harvey, SH Sarni, VH Wysocki
Analytical chemistry 91 (1), 190-209, 2018
902018
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
A Sahasrabuddhe, Y Hsia, F Busch, W Sheffler, NP King, D Baker, ...
Proceedings of the National Academy of Sciences 115 (6), 1268-1273, 2018
742018
Localization of protein complex bound ligands by surface-induced dissociation high-resolution mass spectrometry
F Busch, ZL VanAernum, Y Ju, J Yan, JD Gilbert, RS Quintyn, M Bern, ...
Analytical chemistry 90 (21), 12796-12801, 2018
452018
Ancestral tryptophan synthase reveals functional sophistication of primordial enzyme complexes
F Busch, C Rajendran, K Heyn, S Schlee, R Merkl, R Sterner
Cell chemical biology 23 (6), 709-715, 2016
452016
Analysis of allosteric communication in a multienzyme complex by ancestral sequence reconstruction
M Schupfner, K Straub, F Busch, R Merkl, R Sterner
Proceedings of the National Academy of Sciences 117 (1), 346-354, 2020
432020
Light regulation of enzyme allostery through photo-responsive unnatural amino acids
AC Kneuttinger, K Straub, P Bittner, NA Simeth, A Bruckmann, F Busch, ...
Cell chemical biology 26 (11), 1501-1514. e9, 2019
362019
Oligomerization affects the ability of human cyclase-associated proteins 1 and 2 to promote actin severing by cofilins
V Purde, F Busch, E Kudryashova, VH Wysocki, DS Kudryashov
International journal of molecular sciences 20 (22), 5647, 2019
332019
Generation of ordered protein assemblies using rigid three-body fusion
I Vulovic, Q Yao, YJ Park, A Courbet, A Norris, F Busch, A Sahasrabuddhe, ...
Proceedings of the National Academy of Sciences 118 (23), e2015037118, 2021
322021
Accurate and automated high-coverage identification of chemically cross-linked peptides with MaxLynx
S Yılmaz, F Busch, N Nagaraj, J Cox
Analytical Chemistry 94 (3), 1608-1617, 2022
242022
Evolutionary diversification of protein–protein interactions by interface add-ons
MG Plach, F Semmelmann, F Busch, M Busch, L Heizinger, VH Wysocki, ...
Proceedings of the National Academy of Sciences 114 (40), E8333-E8342, 2017
242017
De novo design of tyrosine and serine kinase-driven protein switches
NB Woodall, Z Weinberg, J Park, F Busch, RS Johnson, MJ Feldbauer, ...
Nature structural & molecular biology 28 (9), 762-770, 2021
192021
Transferrin receptor targeting by de novo sheet extension
DD Sahtoe, A Coscia, N Mustafaoglu, LM Miller, D Olal, I Vulovic, TY Yu, ...
Proceedings of the National Academy of Sciences 118 (17), e2021569118, 2021
192021
Protein quaternary structures in solution are a mixture of multiple forms
S Marciano, D Dey, D Listov, SJ Fleishman, A Sonn-Segev, H Mertens, ...
Chemical Science 13 (39), 11680-11695, 2022
172022
Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
S Landeras-Bueno, H Wasserman, G Oliveira, ZL VanAernum, F Busch, ...
Cell reports 35 (2), 2021
162021
Analysis of tagged proteins using tandem affinity-buffer exchange chromatography online with native mass spectrometry
F Busch, ZL VanAernum, SM Lai, V Gopalan, VH Wysocki
Biochemistry 60 (24), 1876-1884, 2021
132021
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Articles 1–20