Rudi Fasan
Rudi Fasan
Andrew S. Kende Professor of Chemistry, Department of Chemistry, University of Rochester
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Zitiert von
Zitiert von
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
R Fasan, MM Chen, NC Crook, FH Arnold
Angewandte Chemie International Edition 46 (44), 8414-8418, 2007
Tuning P450 enzymes as oxidation catalysts
R Fasan
ACS Catalysis 2 (4), 647-666, 2012
Molecular basis of RNA recognition by the human alternative splicing factor Fox‐1
SD Auweter, R Fasan, L Reymond, JG Underwood, DL Black, S Pitsch, ...
The EMBO journal 25 (1), 163-173, 2006
Using a β‐hairpin to mimic an α‐helix: cyclic peptidomimetic inhibitors of the p53–HDM2 protein–protein interaction
R Fasan, RLA Dias, K Moehle, O Zerbe, JW Vrijbloed, D Obrecht, ...
Angewandte Chemie International Edition 43 (16), 2109-2112, 2004
Evolutionary history of a specialized P450 propane monooxygenase
R Fasan, YT Meharenna, CD Snow, TL Poulos, FH Arnold
Journal of molecular biology 383 (5), 1069-1080, 2008
Highly diastereoselective and enantioselective olefin cyclopropanation using engineered myoglobin‐based catalysts
M Bordeaux, V Tyagi, R Fasan
Angewandte Chemie 127 (6), 1764-1768, 2015
Structure–Activity Studies in a Family of β‐Hairpin Protein Epitope Mimetic Inhibitors of the p53–HDM2 Protein–Protein Interaction
R Fasan, RLA Dias, K Moehle, O Zerbe, D Obrecht, PRE Mittl, MG Grütter, ...
ChemBioChem 7 (3), 515-526, 2006
Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions
OF Brandenberg, R Fasan, FH Arnold
Current opinion in biotechnology 47, 102-111, 2017
Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity
K Zhang, BM Shafer, MD Demars, HA Stern, R Fasan
Journal of the American Chemical Society 134 (45), 18695-18704, 2012
P450-Catalyzed Intramolecular sp3 C–H Amination with Arylsulfonyl Azide Substrates
R Singh, M Bordeaux, R Fasan
ACS catalysis 4 (2), 546-552, 2014
Intermolecular carbene S–H insertion catalysed by engineered myoglobin-based catalysts
V Tyagi, RB Bonn, R Fasan
Chemical Science 6 (4), 2488-2494, 2015
Chemo-enzymatic fluorination of unactivated organic compounds
A Rentmeister, FH Arnold, R Fasan
Nature chemical biology 5 (1), 26-28, 2009
Myoglobin-catalyzed intermolecular carbene N–H insertion with arylamine substrates
G Sreenilayam, R Fasan
Chemical Communications 51 (8), 1532-1534, 2015
Enzymatic C(sp3)-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones
R Singh, JN Kolev, PA Sutera, R Fasan
ACS catalysis 5 (3), 1685-1691, 2015
Gram‐scale synthesis of chiral cyclopropane‐containing drugs and drug precursors with engineered myoglobin catalysts featuring complementary stereoselectivity
P Bajaj, G Sreenilayam, V Tyagi, R Fasan
Angewandte Chemie 128 (52), 16344-16348, 2016
Highly diastereo-and enantioselective synthesis of trifluoromethyl-substituted cyclopropanes via myoglobin-catalyzed transfer of trifluoromethylcarbene
A Tinoco, V Steck, V Tyagi, R Fasan
Journal of the American Chemical Society 139 (15), 5293-5296, 2017
Myoglobin‐Catalyzed Olefination of Aldehydes
V Tyagi, R Fasan
Angewandte Chemie 128 (7), 2558-2562, 2016
Intramolecular C (sp3) H amination of arylsulfonyl azides with engineered and artificial myoglobin-based catalysts
M Bordeaux, R Singh, R Fasan
Bioorganic & medicinal chemistry 22 (20), 5697-5704, 2014
P450 fingerprinting method for rapid discovery of terpene hydroxylating P450 catalysts with diversified regioselectivity
K Zhang, S El Damaty, R Fasan
Journal of the American Chemical Society 133 (10), 3242-3245, 2011
Protein ligand design: from phage display to synthetic protein epitope mimetics in human antibody Fc-binding peptidomimetics
RLA Dias, R Fasan, K Moehle, A Renard, D Obrecht, JA Robinson
Journal of the American Chemical Society 128 (8), 2726-2732, 2006
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