| 11-Deoxycorticosterone Is a Potent Agonist of the Rainbow Trout (Oncorhynchus mykiss) Mineralocorticoid Receptor A Sturm, N Bury, L Dengreville, J Fagart, G Flouriot, ME Rafestin-Oblin, ... Endocrinology 146 (1), 47-55, 2005 | 261 | 2005 |
| A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule J Fagart, A Hillisch, J Huyet, L Bärfacker, M Fay, U Pleiss, E Pook, ... Journal of Biological Chemistry 285 (39), 29932-29940, 2010 | 199 | 2010 |
| Antagonism in the human mineralocorticoid receptor J Fagart, JM Wurtz, A Souque, C Hellal‐Levy, D Moras, ... The EMBO journal, 1998 | 191 | 1998 |
| Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors C Hellal-Levy, B Couette, J Fagart, A Souque, C Gomez-Sanchez, ... FEBS letters 464 (1-2), 9-13, 1999 | 185 | 1999 |
| Finerenone impedes aldosterone-dependent nuclear import of the mineralocorticoid receptor and prevents genomic recruitment of steroid receptor coactivator-1 L Amazit, F Le Billan, P Kolkhof, K Lamribet, S Viengchareun, MR Fay, ... Journal of Biological Chemistry 290 (36), 21876-21889, 2015 | 157 | 2015 |
| Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension J Fagart, J Huyet, GM Pinon, M Rochel, C Mayer, ME Rafestin-Oblin Nature structural & molecular biology 12 (6), 554-555, 2005 | 146 | 2005 |
| Identification of multiple gene mutations accounts for a new genetic architecture of primary ovarian insufficiency J Bouilly, I Beau, S Barraud, V Bernard, K Azibi, J Fagart, A Fèvre, ... The Journal of Clinical Endocrinology & Metabolism 101 (12), 4541-4550, 2016 | 124 | 2016 |
| Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosis C Taillé, S Grootenboer-Mignot, C Boursier, L Michel, MP Debray, ... American journal of respiratory and critical care medicine 183 (6), 759-766, 2011 | 117 | 2011 |
| The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related ME Rafestin-Oblin, A Souque, B Bocchi, G Pinon, J Fagart, A Vandewalle Endocrinology 144 (2), 528-533, 2003 | 115 | 2003 |
| Normosmic congenital hypogonadotropic hypogonadism due to TAC3/TACR3 mutations: characterization of neuroendocrine phenotypes and novel mutations B Francou, J Bouligand, A Voican, L Amazit, S Trabado, J Fagart, ... PloS one 6 (10), e25614, 2011 | 111 | 2011 |
| Mechanistic aspects of mineralocorticoid receptor activation C Hellal-Levy, J Fagart, A Souque, ME Rafestin-Oblin Kidney International 57 (4), 1250-1255, 2000 | 100 | 2000 |
| Mineralocorticoid receptor mutations are the principal cause of renal type 1 pseudohypoaldosteronism L Pujo, J Fagart, F Gary, DT Papadimitriou, A Claës, X Jeunemaître, ... Human mutation 28 (1), 33-40, 2007 | 90 | 2007 |
| A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach JM Wurtz, B Guillot, J Fagart, D Moras, K Tietjen, M Schindler Protein Science 9 (6), 1073-1084, 2000 | 81 | 2000 |
| ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure C Delcour, L Amazit, LC Patino, F Magnin, J Fagart, B Delemer, J Young, ... Genetics in Medicine 21 (4), 930-938, 2019 | 79 | 2019 |
| Cistrome of the aldosterone‐activated mineralocorticoid receptor in human renal cells F Le Billan, JA Khan, K Lamribet, S Viengchareun, J Bouligand, J Fagart, ... The FASEB Journal 29 (9), 3977-3989, 2015 | 74 | 2015 |
| Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure B COUETTE, J FAGART, S JALAGUIER, M LOMBES, A SOUQUE, ... Biochemical Journal 315 (2), 421-427, 1996 | 73 | 1996 |
| Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor C Hellal-Levy, J Fagart, A Souque, JM Wurtz, D Moras, ME Rafestin-Oblin Molecular Endocrinology 14 (8), 1210-1221, 2000 | 71 | 2000 |
| Familial Multiplicity of Estrogen Insensitivity Associated With a Loss-of-Function ESR1 Mutation V Bernard, S Kherra, B Francou, J Fagart, S Viengchareun, J Guéchot, ... The journal of clinical endocrinology & metabolism 102 (1), 93-99, 2017 | 66 | 2017 |
| Folding requirements of the ligand-binding domain of the human mineralocorticoid receptor B Couette, S Jalaguier, C Hellal-Levy, B Lupo, J Fagart, G Auzou, ... Molecular Endocrinology 12 (6), 855-863, 1998 | 61 | 1998 |
| Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies N Kumar, J Fagart, P Liere, SJ Mitchell, AR Knibb, I Petit-Topin, M Rame, ... Endocrinology 158 (1), 170-182, 2017 | 57 | 2017 |
