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Jerome Fagart
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11-Deoxycorticosterone Is a Potent Agonist of the Rainbow Trout (Oncorhynchus mykiss) Mineralocorticoid Receptor
A Sturm, N Bury, L Dengreville, J Fagart, G Flouriot, ME Rafestin-Oblin, ...
Endocrinology 146 (1), 47-55, 2005
2512005
A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule
J Fagart, A Hillisch, J Huyet, L Bärfacker, M Fay, U Pleiss, E Pook, ...
Journal of Biological Chemistry 285 (39), 29932-29940, 2010
1882010
Antagonism in the human mineralocorticoid receptor
J Fagart, JM Wurtz, A Souque, C Hellal‐Levy, D Moras, ...
The EMBO journal, 1998
1851998
Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors
C Hellal-Levy, B Couette, J Fagart, A Souque, C Gomez-Sanchez, ...
FEBS letters 464 (1-2), 9-13, 1999
1761999
Finerenone impedes aldosterone-dependent nuclear import of the mineralocorticoid receptor and prevents genomic recruitment of steroid receptor coactivator-1
L Amazit, F Le Billan, P Kolkhof, K Lamribet, S Viengchareun, MR Fay, ...
Journal of Biological Chemistry 290 (36), 21876-21889, 2015
1412015
Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension
J Fagart, J Huyet, GM Pinon, M Rochel, C Mayer, ME Rafestin-Oblin
Nature structural & molecular biology 12 (6), 554-555, 2005
1392005
Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosis
C Taillé, S Grootenboer-Mignot, C Boursier, L Michel, MP Debray, ...
American journal of respiratory and critical care medicine 183 (6), 759-766, 2011
1172011
Normosmic congenital hypogonadotropic hypogonadism due to TAC3/TACR3 mutations: characterization of neuroendocrine phenotypes and novel mutations
B Francou, J Bouligand, A Voican, L Amazit, S Trabado, J Fagart, ...
PloS one 6 (10), e25614, 2011
1112011
The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related
ME Rafestin-Oblin, A Souque, B Bocchi, G Pinon, J Fagart, A Vandewalle
Endocrinology 144 (2), 528-533, 2003
1092003
Identification of multiple gene mutations accounts for a new genetic architecture of primary ovarian insufficiency
J Bouilly, I Beau, S Barraud, V Bernard, K Azibi, J Fagart, A Fèvre, ...
The Journal of Clinical Endocrinology & Metabolism 101 (12), 4541-4550, 2016
1072016
Mechanistic aspects of mineralocorticoid receptor activation
C Hellal-Levy, J Fagart, A Souque, ME Rafestin-Oblin
Kidney international 57 (4), 1250-1255, 2000
982000
Mineralocorticoid receptor mutations are the principal cause of renal type 1 pseudohypoaldosteronism
L Pujo, J Fagart, F Gary, DT Papadimitriou, A Claës, X Jeunemaitre, ...
Human mutation 28 (1), 33-40, 2007
842007
A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach
JM Wurtz, B Guillot, J Fagart, D Moras, K Tietjen, M Schindler
Protein Science 9 (6), 1073-1084, 2000
822000
Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor
C Hellal-Levy, J Fagart, A Souque, JM Wurtz, D Moras, ME Rafestin-Oblin
Molecular Endocrinology 14 (8), 1210-1221, 2000
722000
Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure
B COUETTE, J FAGART, S JALAGUIER, M LOMBES, A SOUQUE, ...
Biochemical Journal 315 (2), 421-427, 1996
711996
Cistrome of the aldosterone‐activated mineralocorticoid receptor in human renal cells
F Le Billan, JA Khan, K Lamribet, S Viengchareun, J Bouligand, J Fagart, ...
The FASEB Journal 29 (9), 3977-3989, 2015
702015
ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure
C Delcour, L Amazit, LC Patino, F Magnin, J Fagart, B Delemer, J Young, ...
Genetics in Medicine 21 (4), 930-938, 2019
652019
Familial Multiplicity of Estrogen Insensitivity Associated With a Loss-of-Function ESR1 Mutation
V Bernard, S Kherra, B Francou, J Fagart, S Viengchareun, J Guéchot, ...
The Journal of Clinical Endocrinology & Metabolism 102 (1), 93-99, 2017
602017
Folding requirements of the ligand-binding domain of the human mineralocorticoid receptor
B Couette, S Jalaguier, C Hellal-Levy, B Lupo, J Fagart, G Auzou, ...
Molecular Endocrinology 12 (6), 855-863, 1998
601998
The mineralocorticoid activity of progesterone derivatives depends on the nature of the C18 substituent
A Souque, J Fagart, B Couette, E Davioud, F Sobrio, A Marquet, ...
Endocrinology 136 (12), 5651-5658, 1995
561995
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