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Qasim Rafiq
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Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor
QA Rafiq, KM Brosnan, K Coopman, AW Nienow, CJ Hewitt
Biotechnology letters 35, 1233-1245, 2013
2232013
A potentially scalable method for the harvesting of hMSCs from microcarriers
AW Nienow, QA Rafiq, K Coopman, CJ Hewitt
Biochemical Engineering Journal 85, 79-88, 2014
1792014
Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors
QA Rafiq, K Coopman, AW Nienow, CJ Hewitt
Biotechnology journal 11 (4), 473-486, 2016
1582016
Antimicrobial resistance mechanisms and potential synthetic treatments
J Ali, QA Rafiq, E Ratcliffe
Future science OA 4 (4), FSO290, 2018
1442018
Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum‐free microcarrier process
TRJ Heathman, VAM Glyn, A Picken, QA Rafiq, K Coopman, AW Nienow, ...
Biotechnology and bioengineering 112 (8), 1696-1707, 2015
1052015
Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development
TRJ Heathman, QA Rafiq, AKC Chan, K Coopman, AW Nienow, B Kara, ...
Biochemical engineering journal 108, 14-23, 2016
1022016
Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms
AW Nienow, CJ Hewitt, TRJ Heathman, VAM Glyn, GN Fonte, MP Hanga, ...
Biochemical Engineering Journal 108, 24-29, 2016
1002016
Scale-up of human mesenchymal stem cell culture: current technologies and future challenges
QA Rafiq, K Coopman, CJ Hewitt
Current Opinion in Chemical Engineering 2 (1), 8-16, 2013
852013
Decentralised manufacturing of cell and gene therapy products: Learning from other healthcare sectors
RP Harrison, S Ruck, QA Rafiq, N Medcalf
Biotechnology advances 36 (2), 345-357, 2018
692018
Lentiviral vectors for T cell engineering: clinical applications, bioprocessing and future perspectives
RP Labbé, S Vessillier, QA Rafiq
Viruses 13 (8), 1528, 2021
622021
Decentralized manufacturing of cell and gene therapies: Overcoming challenges and identifying opportunities
RP Harrison, S Ruck, N Medcalf, QA Rafiq
Cytotherapy 19 (10), 1140-1151, 2017
602017
Cell therapy-processing economics: small-scale microfactories as a stepping stone toward large-scale macrofactories
RP Harrison, N Medcalf, QA Rafiq
Regenerative medicine 13 (2), 159-173, 2018
522018
Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate
TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ...
Cytotherapy 18 (4), 523-535, 2016
522016
Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: Utilising the phenomenon to improve …
QA Rafiq, S Ruck, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ...
Biochemical engineering journal 135, 11-21, 2018
492018
Process development of human multipotent stromal cell microcarrier culture using an automated high‐throughput microbioreactor
QA Rafiq, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ...
Biotechnology and bioengineering 114 (10), 2253-2266, 2017
492017
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds
PS Couto, MC Rotondi, A Bersenev, CJ Hewitt, AW Nienow, F Verter, ...
Biotechnology Advances 45, 107636, 2020
482020
Centralised versus decentralised manufacturing and the delivery of healthcare products: A United Kingdom exemplar
RP Harrison, QA Rafiq, N Medcalf
Cytotherapy 20 (6), 873-890, 2018
482018
Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production
TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ...
Cytotherapy 17 (11), 1524-1535, 2015
472015
Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development
TRJ Heathman, AW Nienow, QA Rafiq, K Coopman, B Kara, CJ Hewitt
Biochemical Engineering Journal 136, 9-17, 2018
352018
Developing an automated robotic factory for novel stem cell therapy production
QA Rafiq, K Twomey, M Kulik, C Leschke, J O'dea, S Callens, C Gentili, ...
Regenerative medicine 11 (4), 351-354, 2016
332016
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