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Miguel Ganuza
Miguel Ganuza
Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London
Bestätigte E-Mail-Adresse bei qmul.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion
M Ganuza, C Sáiz‐Ladera, M Cañamero, G Gómez, R Schneider, ...
The EMBO journal 31 (11), 2498-2510, 2012
1092012
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ...
Cell stem cell 29 (8), 1273-1284. e8, 2022
982022
Functional screen identifies regulators of murine hematopoietic stem cell repopulation
P Holmfeldt, M Ganuza, H Marathe, B He, T Hall, G Kang, J Moen, ...
Journal of Experimental Medicine 213 (3), 433-449, 2016
982016
Lifelong haematopoiesis is established by hundreds of precursors throughout mammalian ontogeny
M Ganuza, T Hall, D Finkelstein, A Chabot, G Kang, S McKinney-Freeman
Nature cell biology 19 (10), 1153-1163, 2017
742017
The global clonal complexity of the murine blood system declines throughout life and after serial transplantation
M Ganuza, T Hall, D Finkelstein, YD Wang, A Chabot, G Kang, W Bi, G Wu, ...
Blood, The Journal of the American Society of Hematology 133 (18), 1927-1942, 2019
552019
Murine foetal liver supports limited detectable expansion of life-long haematopoietic progenitors
M Ganuza, T Hall, J Myers, C Nevitt, R Sánchez-Lanzas, A Chabot, J Ding, ...
Nature cell biology 24 (10), 1475-1486, 2022
282022
Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
M Ganuza, A Chabot, X Tang, W Bi, S Natarajan, R Carter, C Gawad, ...
Nature communications 9 (1), 5405, 2018
262018
Hematopoietic stem cells under pressure
M Ganuza, S McKinney-Freeman
Current opinion in hematology 24 (4), 314-321, 2017
222017
Murine hemogenic endothelial precursors display heterogeneous hematopoietic potential ex vivo
M Ganuza, B Hadland, A Chabot, C Li, G Kang, I Bernstein, ...
Experimental hematology 51, 25-35. e6, 2017
192017
Nfix Promotes Survival of Immature Hematopoietic Cells via Regulation of c-Mpl
T Hall, M Walker, M Ganuza, P Holmfeldt, M Bordas, G Kang, W Bi, ...
Stem Cells 36 (6), 943-950, 2018
152018
Clones assemble! The clonal complexity of blood during ontogeny and disease
M Ganuza, T Hall, EA Obeng, S McKinney-Freeman
Experimental hematology 83, 35-47, 2020
132020
Cdk7: open questions beyond the prevailing model
M Ganuza, D Santamaría
Cell Cycle 11 (19), 3519-3520, 2012
82012
Diversity in the bone marrow niche: classic and novel strategies to uncover niche composition
R Sánchez‐Lanzas, F Kalampalika, M Ganuza
British Journal of Haematology 199 (5), 647-664, 2022
62022
Specification of hematopoietic stem cells in mammalian embryos: a rare or frequent event?
M Ganuza, W Clements, S McKinney-Freeman
Blood, The Journal of the American Society of Hematology 140 (4), 309-320, 2022
52022
The G Protein-Coupled Receptor Associated Sorting Proteins, Gprasp2 and Armcx1 Are Putative Negative Regulators of HSC Engraftment and Repopulation
M Ferdous, M Ganuza, P Holmfeldt, T Hall, M Walker, ...
Blood, The Journal of the American Society of Hematology 126 (23), 2386-2386, 2015
12015
Haematopoietic stem cell health in sickle cell disease and its implications for stem cell therapies and secondary haematological disorders
V Gorur, KR Kranc, M Ganuza, P Telfer
Blood Reviews, 101137, 2023
2023
GENETIC IDENTIFICATION OF THE CELLULAR INTERACTOME THAT SUPPORTS T-CELL DEVELOPMENT IN THE THYMUS
M Ganuza, R Sanchez-Lanzas, A Jimenez-Pompa, M Efremova
2023
3167–NOTCH3 C455R EXPRESSION IN THE MURINE HEMATOPOIETIC SYSTEM RESULTS IN CLONAL HAEMATOPOIESIS AND A PERTURBED INFLAMMATORY MILIEU
R Sanchez-Lanzas, F Kalampalika, J Barclay, A Jimenez-Pompa, ...
Experimental Hematology 124, S133, 2023
2023
1009–GENETIC IDENTIFICATION OF THE CELLULAR INTERACTOME THAT SUPPORTS T-CELL DEVELOPMENT IN THE THYMUS
M Ganuza, R Sanchez-Lanzas, A Jimenez-Pompa, M Efremova
Experimental Hematology 124, S24, 2023
2023
CLONAL DYNAMICS OF EMBRYONIC AND EARLY-POST-BIRTH BLOOD PRECURSORS
M Ganuza, A Chabot, D Finkelstein, S McKinney-Freeman
Experimental Hematology 76, S66, 2019
2019
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