Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion M Ganuza, C Sáiz‐Ladera, M Cañamero, G Gómez, R Schneider, ... The EMBO journal 31 (11), 2498-2510, 2012 | 109 | 2012 |
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ... Cell stem cell 29 (8), 1273-1284. e8, 2022 | 98 | 2022 |
Functional screen identifies regulators of murine hematopoietic stem cell repopulation P Holmfeldt, M Ganuza, H Marathe, B He, T Hall, G Kang, J Moen, ... Journal of Experimental Medicine 213 (3), 433-449, 2016 | 98 | 2016 |
Lifelong haematopoiesis is established by hundreds of precursors throughout mammalian ontogeny M Ganuza, T Hall, D Finkelstein, A Chabot, G Kang, S McKinney-Freeman Nature cell biology 19 (10), 1153-1163, 2017 | 74 | 2017 |
The global clonal complexity of the murine blood system declines throughout life and after serial transplantation M Ganuza, T Hall, D Finkelstein, YD Wang, A Chabot, G Kang, W Bi, G Wu, ... Blood, The Journal of the American Society of Hematology 133 (18), 1927-1942, 2019 | 55 | 2019 |
Murine foetal liver supports limited detectable expansion of life-long haematopoietic progenitors M Ganuza, T Hall, J Myers, C Nevitt, R Sánchez-Lanzas, A Chabot, J Ding, ... Nature cell biology 24 (10), 1475-1486, 2022 | 28 | 2022 |
Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs M Ganuza, A Chabot, X Tang, W Bi, S Natarajan, R Carter, C Gawad, ... Nature communications 9 (1), 5405, 2018 | 26 | 2018 |
Hematopoietic stem cells under pressure M Ganuza, S McKinney-Freeman Current opinion in hematology 24 (4), 314-321, 2017 | 22 | 2017 |
Murine hemogenic endothelial precursors display heterogeneous hematopoietic potential ex vivo M Ganuza, B Hadland, A Chabot, C Li, G Kang, I Bernstein, ... Experimental hematology 51, 25-35. e6, 2017 | 19 | 2017 |
Nfix Promotes Survival of Immature Hematopoietic Cells via Regulation of c-Mpl T Hall, M Walker, M Ganuza, P Holmfeldt, M Bordas, G Kang, W Bi, ... Stem Cells 36 (6), 943-950, 2018 | 15 | 2018 |
Clones assemble! The clonal complexity of blood during ontogeny and disease M Ganuza, T Hall, EA Obeng, S McKinney-Freeman Experimental hematology 83, 35-47, 2020 | 13 | 2020 |
Cdk7: open questions beyond the prevailing model M Ganuza, D Santamaría Cell Cycle 11 (19), 3519-3520, 2012 | 8 | 2012 |
Diversity in the bone marrow niche: classic and novel strategies to uncover niche composition R Sánchez‐Lanzas, F Kalampalika, M Ganuza British Journal of Haematology 199 (5), 647-664, 2022 | 6 | 2022 |
Specification of hematopoietic stem cells in mammalian embryos: a rare or frequent event? M Ganuza, W Clements, S McKinney-Freeman Blood, The Journal of the American Society of Hematology 140 (4), 309-320, 2022 | 5 | 2022 |
The G Protein-Coupled Receptor Associated Sorting Proteins, Gprasp2 and Armcx1 Are Putative Negative Regulators of HSC Engraftment and Repopulation M Ferdous, M Ganuza, P Holmfeldt, T Hall, M Walker, ... Blood, The Journal of the American Society of Hematology 126 (23), 2386-2386, 2015 | 1 | 2015 |
Haematopoietic stem cell health in sickle cell disease and its implications for stem cell therapies and secondary haematological disorders V Gorur, KR Kranc, M Ganuza, P Telfer Blood Reviews, 101137, 2023 | | 2023 |
GENETIC IDENTIFICATION OF THE CELLULAR INTERACTOME THAT SUPPORTS T-CELL DEVELOPMENT IN THE THYMUS M Ganuza, R Sanchez-Lanzas, A Jimenez-Pompa, M Efremova | | 2023 |
3167–NOTCH3 C455R EXPRESSION IN THE MURINE HEMATOPOIETIC SYSTEM RESULTS IN CLONAL HAEMATOPOIESIS AND A PERTURBED INFLAMMATORY MILIEU R Sanchez-Lanzas, F Kalampalika, J Barclay, A Jimenez-Pompa, ... Experimental Hematology 124, S133, 2023 | | 2023 |
1009–GENETIC IDENTIFICATION OF THE CELLULAR INTERACTOME THAT SUPPORTS T-CELL DEVELOPMENT IN THE THYMUS M Ganuza, R Sanchez-Lanzas, A Jimenez-Pompa, M Efremova Experimental Hematology 124, S24, 2023 | | 2023 |
CLONAL DYNAMICS OF EMBRYONIC AND EARLY-POST-BIRTH BLOOD PRECURSORS M Ganuza, A Chabot, D Finkelstein, S McKinney-Freeman Experimental Hematology 76, S66, 2019 | | 2019 |