D. Allan Drummond
D. Allan Drummond
Associate Professor, Biochemistry and Molecular Biology, Genetic Medicine
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution
DA Drummond, CO Wilke
Cell 134 (2), 341-352, 2008
Why highly expressed proteins evolve slowly
DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005
Stress-triggered phase separation is an adaptive, evolutionarily tuned response
JA Riback, CD Katanski, JL Kear-Scott, EV Pilipenko, AE Rojek, ...
Cell 168 (6), 1028-1040, 2017
The evolutionary consequences of erroneous protein synthesis
D Allan Drummond, CO Wilke
Nature Reviews Genetics 10 (10), 715-724, 2009
Reversible, specific, active aggregates of endogenous proteins assemble upon heat stress
EWJ Wallace, JL Kear-Scott, EV Pilipenko, MH Schwartz, PR Laskowski, ...
Cell 162 (6), 1286-1298, 2015
A single determinant dominates the rate of yeast protein evolution
DA Drummond, A Raval, CO Wilke
Molecular biology and evolution 23 (2), 327-337, 2006
Thermodynamic prediction of protein neutrality
JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast
KA Geiler-Samerotte, MF Dion, BA Budnik, SM Wang, DL Hartl, ...
Proceedings of the National Academy of Sciences 108 (2), 680-685, 2011
A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments
Y Li, DA Drummond, AM Sawayama, CD Snow, JD Bloom, FH Arnold
Nature Biotechnology 25 (9), 1051-1056, 2007
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins
DA Drummond, BL Iverson, G Georgiou, FH Arnold
Journal of molecular biology 350 (4), 806-816, 2005
Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
G Csárdi, A Franks, DS Choi, EM Airoldi, DA Drummond
PLOS Genetics 11 (5), e1005206, 2015
Structural determinants of the rate of protein evolution in yeast
JD Bloom, DA Drummond, FH Arnold, CO Wilke
Molecular biology and evolution 23 (9), 1751-1761, 2006
Cellular sensing by phase separation: Using the process, not just the products
H Yoo, C Triandafillou, DA Drummond
Journal of Biological Chemistry 294 (18), 7151-7159, 2019
Good codons, bad transcript: large reductions in gene expression and fitness arising from synonymous mutations in a key enzyme
D Agashe, NC Martinez-Gomez, DA Drummond, CJ Marx
Molecular biology and evolution 30 (3), 549-560, 2013
On the conservative nature of intragenic recombination
DA Drummond, JJ Silberg, MM Meyer, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (15), 5380-5385, 2005
A nutrient-driven tRNA modification alters translational fidelity and genome-wide protein coding across an animal genus
JM Zaborske, VL Bauer DuMont, EWJ Wallace, T Pan, CF Aquadro, ...
PLoS biology 12 (12), e1002015, 2014
Chaperones directly and efficiently disperse stress-triggered biomolecular condensates
H Yoo, JAM Bard, E Pilipenko, DA Drummond
Molecular Cell 82 (4), 741–755, 2022
Contact density affects protein evolutionary rate from bacteria to animals
T Zhou, DA Drummond, CO Wilke
Journal of molecular evolution 66, 395-404, 2008
Transient intracellular acidification regulates the core transcriptional heat shock response
CG Triandafillou, CD Katanski, AR Dinner, DA Drummond
Elife 9, e54880, 2020
Stressful steps: progress and challenges in understanding stress-induced mRNA condensation and accumulation in stress granules
H Glauninger, CJW Hickernell, JAM Bard, DA Drummond
Molecular cell 82 (14), 2544-2556, 2022
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