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Wai Ting Chan
Wai Ting Chan
Centro de Investigaciones Biológicas, CSIC
Bestätigte E-Mail-Adresse bei cib.csic.es
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A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease
A Attar, T Liu, WTC Chan, J Hayes, M Nejad, KC Lei, G Bitan
PloS one 8 (11), e80355, 2013
1562013
Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems
WT Chan, M Espinosa, CC Yeo
Frontiers in molecular biosciences 3, 9, 2016
1522016
Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae
SK Khoo, B Loll, WT Chan, RL Shoeman, L Ngoo, CC Yeo, A Meinhart
Journal of Biological Chemistry 282 (27), 19606-19618, 2007
1342007
One cannot rule them all: Are bacterial toxins-antitoxins druggable?
WT Chan, D Balsa, M Espinosa
FEMS microbiology reviews 39 (4), 522-540, 2015
892015
Toxin-antitoxin genes of the Gram-positive pathogen Streptococcus pneumoniae: so few and yet so many
WT Chan, I Moreno-Córdoba, CC Yeo, M Espinosa
Microbiology and molecular biology reviews 76 (4), 773-791, 2012
892012
The yefM-yoeB Toxin-Antitoxin Systems of Escherichia coli and Streptococcus pneumoniae: Functional and Structural Correlation
C Nieto, I Cherny, SK Khoo, MG de Lacoba, WT Chan, CC Yeo, E Gazit, ...
Journal of bacteriology 189 (4), 1266-1278, 2007
872007
Safety and pharmacological characterization of the molecular tweezer CLR01–a broad-spectrum inhibitor of amyloid proteins’ toxicity
A Attar, WTC Chan, FG Klärner, T Schrader, G Bitan
BMC Pharmacology and Toxicology 15, 1-14, 2014
632014
Genetic Regulation of the yefM-yoeB Toxin-Antitoxin Locus of Streptococcus pneumoniae
WT Chan, C Nieto, JA Harikrishna, SK Khoo, RY Othman, M Espinosa, ...
Journal of bacteriology 193 (18), 4612-4625, 2011
612011
Conditional Activation of Toxin‐Antitoxin Systems: Postsegregational Killing and Beyond
AM Hernández-Arriaga, WT Chan, M Espinosa, R Díaz-Orejas
Plasmids: Biology and Impact in Biotechnology and Discovery, 175-192, 2015
442015
Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operon
WT Chan, CC Yeo, E Sadowy, M Espinosa
Frontiers in microbiology 5, 117538, 2014
432014
The Streptococcus pneumoniae yefM-yoeB and relBE Toxin-Antitoxin Operons Participate in Oxidative Stress and Biofilm Formation
WT Chan, M Domenech, I Moreno-Córdoba, V Navarro-Martínez, C Nieto, ...
Toxins 10 (9), 378, 2018
382018
Heterologous expression of toxins from bacterial toxin-antitoxin systems in eukaryotic cells: strategies and applications
CC Yeo, F Abu Bakar, WT Chan, M Espinosa, JA Harikrishna
Toxins 8 (2), 49, 2016
302016
The Streptococcus pneumoniae pezAT toxin–antitoxin system reduces β-lactam resistance and genetic competence
WT Chan, M Espinosa
Frontiers in Microbiology 7, 209391, 2016
282016
Purification of telluric acid for SNO+ neutrinoless double-beta decay search
S Hans, R Rosero, L Hu, O Chkvorets, WT Chan, S Guan, W Beriguete, ...
Nuclear Instruments and Methods in Physics Research Section A: Accelerators …, 2015
212015
Toxin-Antitoxin Loci in Streptococcus pneumoniae
WT Chan, I Moreno-Córdoba, CC Yeo, M Espinosa
Prokaryotic toxin-antitoxins, 315-339, 2013
102013
Conditional activation of toxin-antitoxin systems: postsegregational killing and beyond. Microbiol. Spectr. 2: PLAS-0009-2013. doi: 10.1128/microbiolspec
AM Hernández-Arriaga, WT Chan, M Espinosa, R Díaz-Orejas
PLAS-0009-2013, 2014
72014
Prokaryotic Toxin-Antitoxins
WT Chan, I Moreno-Córdoba, CC Yeo, M Espinosa
72013
Interactions of the Streptococcus pneumoniae Toxin-Antitoxin RelBE Proteins with Their Target DNA
I Moreno-Córdoba, WT Chan, C Nieto, M Espinosa
Microorganisms 9 (4), 851, 2021
22021
Type II bacterial toxin–antitoxins: hypotheses, facts, and the newfound plethora of the PezAT system
WT Chan, MP Garcillán-Barcia, CC Yeo, M Espinosa
FEMS microbiology reviews 47 (5), fuad052, 2023
12023
Genetic regulation of the yefM-yoeB and pezAT toxin-antitoxin loci of Streptococcus pneumoniae
WT Chan
Institut Sains Biologi, Fakulti Sains, Universiti Malaya, 2011
12011
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