| The E2F transcription factor is a cellular target for the RB protein SP Chellappan, S Hiebert, M Mudryj, JM Horowitz, JR Nevins Cell 65 (6), 1053-1061, 1991 | 1918 | 1991 |
| Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the … S Chellappan, VB Kraus, B Kroger, K Munger, PM Howley, WC Phelps, ... Proceedings of the National Academy of Sciences 89 (10), 4549-4553, 1992 | 849 | 1992 |
| The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. SW Hiebert, SP Chellappan, JM Horowitz, JR Nevins Genes & development 6 (2), 177-185, 1992 | 764 | 1992 |
| Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling G Fusaro, P Dasgupta, S Rastogi, B Joshi, S Chellappan Journal of Biological Chemistry 278 (48), 47853-47861, 2003 | 449 | 2003 |
| Nicotine induces cell proliferation, invasion and epithelial‐mesenchymal transition in a variety of human cancer cell lines P Dasgupta, W Rizwani, S Pillai, R Kinkade, M Kovacs, S Rastogi, ... International Journal of Cancer 124 (1), 36-45, 2009 | 415 | 2009 |
| Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin P Dasgupta, R Kinkade, B Joshi, C DeCook, E Haura, S Chellappan Proceedings of the National Academy of Sciences 103 (16), 6332-6337, 2006 | 380 | 2006 |
| Nicotine induces cell proliferation by β-arrestin–mediated activation of Src and Rb–Raf-1 pathways P Dasgupta, S Rastogi, S Pillai, D Ordonez-Ercan, M Morris, E Haura, ... The Journal of clinical investigation 116 (8), 2208-2217, 2006 | 369 | 2006 |
| Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers C Schaal, SP Chellappan Molecular Cancer Research 12 (1), 14-23, 2014 | 362 | 2014 |
| Interactions of the p107 and Rb proteins with E2F during the cell proliferation response. JK Schwarz, SH Devoto, EJ Smith, SP Chellappan, L Jakoi, JR Nevins The EMBO journal 12 (3), 1013-1020, 1993 | 303 | 1993 |
| Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function S Wang, N Nath, M Adlam, S Chellappan Oncogene 18 (23), 3501-3510, 1999 | 291 | 1999 |
| Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression S Wang, G Fusaro, J Padmanabhan, SP Chellappan Oncogene 21 (55), 8388-8396, 2002 | 279 | 2002 |
| EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer S Singh, J Trevino, N Bora-Singhal, D Coppola, E Haura, S Altiok, ... Molecular cancer 11, 1-15, 2012 | 261 | 2012 |
| Nicotine promotes tumor growth and metastasis in mouse models of lung cancer R Davis, W Rizwani, S Banerjee, M Kovacs, E Haura, D Coppola, ... PloS one 4 (10), e7524, 2009 | 246 | 2009 |
| Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals S Wang, N Nath, G Fusaro, S Chellappan Molecular and cellular biology 19 (11), 7447-7460, 1999 | 218 | 1999 |
| Nicotine-mediated cell proliferation and angiogenesis: new twists to an old story P Dasgupta, SP Chellappan Cell cycle 5 (20), 2324-2328, 2006 | 190 | 2006 |
| Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation S Wang, RN Ghosh, SP Chellappan Molecular and cellular biology 18 (12), 7487-7498, 1998 | 163 | 1998 |
| Glut-1 antibodies induce growth arrest and apoptosis in human cancer cell lines S Rastogi, S Banerjee, S Chellappan, GR Simon Cancer letters 257 (2), 244-251, 2007 | 162 | 2007 |
| YAP1 regulates OCT4 activity and SOX2 expression to facilitate self‐renewal and vascular mimicry of stem‐like cells N Bora‐Singhal, J Nguyen, C Schaal, D Perumal, S Singh, D Coppola, ... Stem cells 33 (6), 1705-1718, 2015 | 158 | 2015 |
| Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases S Wang, N Nath, A Minden, S Chellappan The EMBO journal, 1999 | 158 | 1999 |
| Nicotinic acetylcholine receptor signaling in tumor growth and metastasis S Singh, S Pillai, S Chellappan Journal of oncology 2011, 2011 | 151 | 2011 |
Smitha PillaiResearch Scientist, Moffitt Cancer Center, Tampa, FloridaVerified email at moffitt.org
