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Self-assembling chimeric polypeptide–doxorubicin conjugate nanoparticles that abolish tumours after a single injection
JA MacKay, M Chen, JR McDaniel, W Liu, AJ Simnick, A Chilkoti
Nature materials 8 (12), 993-999, 2009
6852009
Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection
M Chen, M Bouvier
The EMBO journal 26 (6), 1681-1690, 2007
1942007
Gene-directed enzyme prodrug therapy
J Zhang, V Kale, M Chen
The AAPS journal 17, 102-110, 2015
1902015
Injectable intratumoral depot of thermally responsive polypeptide–radionuclide conjugates delays tumor progression in a mouse model
W Liu, JA MacKay, MR Dreher, M Chen, JR McDaniel, AJ Simnick, ...
Journal of controlled Release 144 (1), 2-9, 2010
1312010
Depletion of PD-1-positive cells ameliorates autoimmune disease
P Zhao, P Wang, S Dong, Z Zhou, Y Cao, H Yagita, X He, SG Zheng, ...
Nature biomedical engineering 3 (4), 292-305, 2019
652019
Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma
EM Mastria, M Chen, JR McDaniel, X Li, J Hyun, MW Dewhirst, A Chilkoti
Journal of controlled release 208, 52-58, 2015
652015
The convergent roles of tapasin and HLA-DM in antigen presentation
S Sadegh-Nasseri, M Chen, K Narayan, M Bouvier
Trends in immunology 29 (3), 141-147, 2008
632008
iTEP nanoparticle-delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors
P Zhao, S Dong, J Bhattacharyya, M Chen
Molecular pharmaceutics 11 (8), 2703-2712, 2014
572014
Immune-tolerant elastin-like polypeptides (iTEPs) and their application as CTL vaccine carriers
S Cho, S Dong, KN Parent, M Chen
Journal of drug targeting 24 (4), 328-339, 2016
542016
Discovery of a 19F MRI sensitive salinomycin derivative with high cytotoxicity towards cancer cells
Q Shi, Y Li, S Bo, X Li, P Zhao, Q Liu, Z Yang, H Cong, H Deng, M Chen, ...
Chemical communications 52 (29), 5136-5139, 2016
452016
The calcium-and zinc-responsive regions of calreticulin reside strictly in the N-/C-domain
Y Tan, M Chen, Z Li, K Mabuchi, M Bouvier
Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (5), 745-753, 2006
432006
An iTEP-salinomycin nanoparticle that specifically and effectively inhibits metastases of 4T1 orthotopic breast tumors
P Zhao, G Xia, S Dong, ZX Jiang, M Chen
Biomaterials 93, 1-9, 2016
402016
An albumin-binding polypeptide both targets cytotoxic T lymphocyte vaccines to lymph nodes and boosts vaccine presentation by dendritic cells
P Wang, P Zhao, S Dong, T Xu, X He, M Chen
Theranostics 8 (1), 223, 2018
342018
An Anti-Programmed death-1 antibody (αPD-1) fusion protein that self-assembles into a multivalent and functional αPD-1 nanoparticle
P Zhao, D Atanackovic, S Dong, H Yagita, X He, M Chen
Molecular pharmaceutics 14 (5), 1494-1500, 2017
312017
Immune checkpoints, a novel class of therapeutic targets for autoimmune diseases
Y Zhai, R Moosavi, M Chen
Frontiers in Immunology 12, 645699, 2021
252021
A characterization of the lumenal region of human tapasin reveals the presence of two structural domains
M Chen, WF Stafford, G Diedrich, A Khan, M Bouvier
Biochemistry 41 (49), 14539-14545, 2002
182002
Direct loading of CTL epitopes onto MHC class I complexes on dendritic cell surface in vivo
P Wang, S Dong, P Zhao, X He, M Chen
Biomaterials 182, 92-103, 2018
142018
A comparison study of iTEP nanoparticle-based CTL vaccine carriers revealed a surprise relationship between the stability and efficiency of the carriers
S Dong, T Xu, P Zhao, KN Parent, M Chen
Theranostics 6 (5), 666, 2016
132016
Direct loading of iTEP-delivered CTL epitope onto MHC class I complexes on the dendritic cell surface
S Dong, P Wang, P Zhao, M Chen
Molecular pharmaceutics 14 (10), 3312-3321, 2017
102017
Engineering of a self-adjuvanted iTEP-delivered CTL vaccine
S Dong, T Xu, P Wang, P Zhao, M Chen
Acta Pharmacologica Sinica 38 (6), 914-923, 2017
92017
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