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Rajendra Kumar Gurumurthy
Rajendra Kumar Gurumurthy
Bestätigte E-Mail-Adresse bei mpiib-berlin.mpg.de
Titel
Zitiert von
Zitiert von
Jahr
Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response
C Chumduri, RK Gurumurthy, PK Zadora, Y Mi, TF Meyer
Cell host & microbe 13 (6), 746-758, 2013
1942013
Subversion of host genome integrity by bacterial pathogens
C Chumduri, RK Gurumurthy, R Zietlow, TF Meyer
Nature reviews Molecular cell biology 17 (10), 659-673, 2016
742016
Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia
C Chumduri, RK Gurumurthy, H Berger, O Dietrich, N Kumar, S Koster, ...
Nature cell biology 23 (2), 184-197, 2021
732021
A loss-of-function screen reveals Ras-and Raf-independent MEK-ERK signaling during Chlamydia trachomatis infection
RK Gurumurthy, AP Mäurer, N Machuy, S Hess, KP Pleissner, ...
Science signaling 3 (113), ra21-ra21, 2010
642010
Integrated phosphoproteome and transcriptome analysis reveals chlamydia-induced epithelial-to-mesenchymal transition in host cells
PK Zadora, C Chumduri, K Imami, H Berger, Y Mi, M Selbach, TF Meyer, ...
Cell Reports 26 (5), 1286-1302. e8, 2019
512019
Reduced display of tumor necrosis factor receptor I at the host cell surface supports infection with Chlamydia trachomatis
N Paland, L Bohme, RK Gurumurthy, A Mäurer, AJ Szczepek, T Rudel
Journal of biological chemistry 283 (10), 6438-6448, 2008
472008
Combined human genome-wide RNAi and metabolite analyses identify IMPDH as a host-directed target against Chlamydia infection
M Rother, E Gonzalez, ART da Costa, L Wask, I Gravenstein, M Pardo, ...
Cell host & microbe 23 (5), 661-671. e8, 2018
402018
Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming
S Koster, RK Gurumurthy, N Kumar, PG Prakash, J Dhanraj, S Bayer, ...
Nature Communications 13 (1), 1030, 2022
362022
Chlamydia trachomatis Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling
Y Mi, RK Gurumurthy, PK Zadora, TF Meyer, C Chumduri
MBio 9 (6), 10.1128/mbio. 01465-18, 2018
212018
Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells
LP Sepe, K Hartl, A Iftekhar, H Berger, N Kumar, C Goosmann, S Chopra, ...
MBio 11 (5), 10.1128/mbio. 01911-20, 2020
202020
Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection
RK Gurumurthy, S Koster, N Kumar, TF Meyer, C Chumduri
Nature Protocols 17 (7), 1658-1690, 2022
172022
Dynamin‐mediated lipid acquisition is essential for Chlamydia trachomatis development
RK Gurumurthy, C Chumduri, A Karlas, S Kimmig, E Gonzalez, N Machuy, ...
Molecular Microbiology 94 (1), 186-201, 2014
162014
Transition of Wnt signaling microenvironment delineates the squamo-columnar junction and emergence of squamous metaplasia of the cervix
C Chumduri, RK Gurumurthy, H Berger, S Koster, V Brinkmann, U Klemm, ...
BioRxiv, 443770, 2018
122018
Genotoxic effect of
LP Sepe, K Hartl, A Iftekhar, H Berger, N Kumar, C Goosmann, S Chopra, ...
Salmonella paratyphi, 2020
82020
Spatial organisation and homeostasis of epithelial lineages at the gastroesophageal junction is regulated by the divergent Wnt mucosal microenvironment
N Kumar, RK Gurumurthy, PG Prakash, SM Kurian, C Wentland, ...
bioRxiv, 2021.08. 05.455222, 2021
32021
Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids
S Koster, RK Gurumurthy, H Berger, M Drabkina, HJ Mollenkopf, ...
bioRxiv, 2021.04. 15.439996, 2021
22021
Global assessment of host cell functions involved in the intracellular survival and replication of Chlamydia using RNA interference in human cells
RK Gurumurthy
Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2010
22010
γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids
J Dong, D Holthaus, C Peters, S Koster, M Ehsani, A Quevedo-Olmos, ...
Frontiers in Immunology 14, 1281646, 2023
12023
Spatial analysis of organ-wide RNA, protein expression, and lineage tracing in the female mouse reproductive tract
RK Gurumurthy, N Kumar, C Chumduri
STAR protocols 2 (4), 100969, 2021
12021
Pharmaceutical composition for the treatment of chlamydial infection
RK Gurumurthy, AP MÄURER, TF Meyer, M Rother, N Machuy, ...
12011
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