Eric Fauman
Eric Fauman
Executive Director,Integrative Biology, Internal Medicine Research Unit, Pfizer Worldwide
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
An atlas of genetic influences on human blood metabolites
SY Shin, EB Fauman, AK Petersen, J Krumsiek, R Santos, J Huang, ...
Nature genetics 46 (6), 543-550, 2014
Pharmacology and mechanism of action of pregabalin: the calcium channel α2–δ (alpha2–delta) subunit as a target for antiepileptic drug discovery
CP Taylor, T Angelotti, E Fauman
Epilepsy research 73 (2), 137-150, 2007
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 Å and the complex with tungstate
JA Stuckey, HL Schubert, EB Fauman, ZY Zhang, JE Dixon, MA Saper
Nature 370 (6490), 571-575, 1994
Structure and function of the protein tyrosine phosphatases
EB Fauman, MA Saper
Trends in biochemical sciences 21 (11), 413-417, 1996
Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach
C Menni, E Fauman, I Erte, JRB Perry, G Kastenmüller, SY Shin, ...
Diabetes 62 (12), 4270-4276, 2013
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
EB Fauman, JP Cogswell, B Lovejoy, WJ Rocque, W Holmes, ...
Cell 93 (4), 617-625, 1998
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ...
Nature metabolism 2 (10), 1135-1148, 2020
Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate
WR Montfort, KM Perry, EB Fauman, JS Finer-Moore, GF Maley, L Hardy, ...
Biochemistry 29 (30), 6964-6977, 1990
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
JMM Howson, W Zhao, DR Barnes, WK Ho, R Young, DS Paul, LL Waite, ...
Nature genetics 49 (7), 1113-1119, 2017
RNA methylation under heat shock control
H Bügl, EB Fauman, BL Staker, F Zheng, SR Kushner, MA Saper, ...
Molecular cell 6 (2), 349-360, 2000
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci
E Mountjoy, EM Schmidt, M Carmona, J Schwartzentruber, G Peat, ...
Nature genetics 53 (11), 1527-1533, 2021
The Cys (X) 5Arg catalytic motif in phosphoester hydrolysis
ZY Zhang, Y Wang, L Wu, EB Fauman, JA Stuckey, HL Schubert, ...
Biochemistry 33 (51), 15266-15270, 1994
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
L Folkersen, E Fauman, M Sabater-Lleal, RJ Strawbridge, M Frånberg, ...
PLoS genetics 13 (4), e1006706, 2017
Structure-based druggability assessment—identifying suitable targets for small molecule therapeutics
EB Fauman, BK Rai, ES Huang
Current opinion in chemical biology 15 (4), 463-468, 2011
S-adenosylmethionine-dependent methyltransferases: structures and functions
X Cheng, R Blumenthal
World Scientific, 1999
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases
KM Perry, EB Fauman, JS Finer‐Moore, WR Montfort, GF Maley, F Maley, ...
Proteins: Structure, Function, and Bioinformatics 8 (4), 315-333, 1990
Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design
E Rutenber, EB Fauman, RJ Keenan, S Fong, PS Furth, ...
Journal of Biological Chemistry 268 (21), 15343-15346, 1993
Structure and evolution of AdoMet-dependent methyltransferases
S-Adenosylmethionine-dependent methyltransferases: structures and functions …, 1999
A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes
NR Van Zuydam, E Ahlqvist, N Sandholm, H Deshmukh, NW Rayner, ...
Diabetes 67 (7), 1414-1427, 2018
A ligand‐induced conformational change in the yersinia protein tyrosine phosphatase
HL Schubert, EB Fauman, JA Stuckey, JE Dixon, MA Saper
Protein Science 4 (9), 1904-1913, 1995
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