| A protein interaction network for pluripotency of embryonic stem cells J Wang, S Rao, J Chu, X Shen, DN Levasseur, TW Theunissen, SH Orkin Nature 444 (7117), 364-368, 2006 | 1343 | 2006 |
| Nanog is the gateway to the pluripotent ground state J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ... Cell 138 (4), 722-737, 2009 | 1282 | 2009 |
| Promotion of reprogramming to ground state pluripotency by signal inhibition J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith PLoS biology 6 (10), e253, 2008 | 1053 | 2008 |
| Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system AW Cheng, H Wang, H Yang, L Shi, Y Katz, TW Theunissen, ... Cell research 23 (10), 1163-1171, 2013 | 992 | 2013 |
| Systematic identification of culture conditions for induction and maintenance of naive human pluripotency TW Theunissen, BE Powell, H Wang, M Mitalipova, DA Faddah, J Reddy, ... Cell stem cell 15 (4), 471-487, 2014 | 987 | 2014 |
| Molecular criteria for defining the naive human pluripotent state TW Theunissen, M Friedli, Y He, E Planet, RC O’Neil, S Markoulaki, ... Cell stem cell 19 (4), 502-515, 2016 | 531 | 2016 |
| NANOG-dependent function of TET1 and TET2 in establishment of pluripotency Y Costa, J Ding, TW Theunissen, F Faiola, TA Hore, PV Shliaha, ... Nature 495 (7441), 370-374, 2013 | 488 | 2013 |
| Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency WW Tee, M Pardo, TW Theunissen, L Yu, JS Choudhary, P Hajkova, ... Genes & development 24 (24), 2772-2777, 2010 | 385 | 2010 |
| Stat3 activation is limiting for reprogramming to ground state pluripotency J Yang, AL Van Oosten, TW Theunissen, G Guo, JCR Silva, A Smith Cell stem cell 7 (3), 319-328, 2010 | 273 | 2010 |
| Derivation of trophoblast stem cells from naïve human pluripotent stem cells C Dong, M Beltcheva, P Gontarz, B Zhang, P Popli, LA Fischer, SA Khan, ... elife 9, e52504, 2020 | 262 | 2020 |
| Hominoid-specific transposable elements and KZFPs facilitate human embryonic genome activation and control transcription in naive human ESCs J Pontis, E Planet, S Offner, P Turelli, J Duc, A Coudray, TW Theunissen, ... Cell stem cell 24 (5), 724-735. e5, 2019 | 243 | 2019 |
| Human naive pluripotent stem cells model X chromosome dampening and X inactivation A Sahakyan, R Kim, C Chronis, S Sabri, G Bonora, TW Theunissen, ... Cell stem cell 20 (1), 87-101, 2017 | 238 | 2017 |
| A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages A Radzisheuskaya, G Le Bin Chia, RL Dos Santos, TW Theunissen, ... Nature cell biology 15 (6), 579-590, 2013 | 233 | 2013 |
| Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions TW Theunissen, AL Van Oosten, G Castelo-Branco, J Hall, A Smith, ... Current Biology 21 (1), 65-71, 2011 | 196 | 2011 |
| Molecular control of induced pluripotency TW Theunissen, R Jaenisch Cell stem cell 14 (6), 720-734, 2014 | 171 | 2014 |
| The transcriptional network controlling pluripotency in ES cells SH Orkin, J Wang, J Kim, J Chu, S Rao, TW Theunissen, X Shen, ... Cold Spring Harbor symposia on quantitative biology 73, 195-202, 2008 | 121 | 2008 |
| Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens RM Karvas, SA Khan, S Verma, Y Yin, D Kulkarni, C Dong, K Park, ... Cell Stem Cell 29 (5), 810-825. e8, 2022 | 102 | 2022 |
| Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain TW Theunissen, Y Costa, A Radzisheuskaya, AL van Oosten, F Lavial, ... Development 138 (22), 4853-4865, 2011 | 92 | 2011 |
| Mechanisms of gene regulation in human embryos and pluripotent stem cells TW Theunissen, R Jaenisch Development 144 (24), 4496-4509, 2017 | 79 | 2017 |
| Switching on pluripotency: a perspective on the biological requirement of Nanog TW Theunissen, JCR Silva Philosophical Transactions of the Royal Society B: Biological Sciences 366 …, 2011 | 55 | 2011 |
