| Mettl1/Wdr4-mediated m7G tRNA methylome is required for normal mRNA translation and embryonic stem cell self-renewal and differentiation S Lin, Q Liu, VS Lelyveld, J Choe, JW Szostak, RI Gregory Molecular cell 71 (2), 244-255. e5, 2018 | 313 | 2018 |
| A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L J Hemelaar, VS Lelyveld, BM Kessler, HL Ploegh Journal of Biological Chemistry 278 (51), 51841, 2003 | 307 | 2003 |
| Enhanced nonenzymatic RNA copying with 2-aminoimidazole activated nucleotides L Li, N Prywes, CP Tam, DK O’flaherty, VS Lelyveld, EC Izgu, A Pal, ... Journal of the American Chemical Society 139 (5), 1810-1813, 2017 | 158 | 2017 |
| Molecular-level functional magnetic resonance imaging of dopaminergic signaling T Lee, LX Cai, VS Lelyveld, A Hai, A Jasanoff Science 344 (6183), 533-535, 2014 | 131 | 2014 |
| Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity VS Lelyveld, E Brustad, FH Arnold, A Jasanoff Journal of the American Chemical Society, 2011 | 96 | 2011 |
| N-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes EC Izgu, A Björkbom, NP Kamat, VS Lelyveld, W Zhang, TZ Jia, ... Journal of the American Chemical Society 138 (51), 16669-16676, 2016 | 60 | 2016 |
| Oligomerization and neurotoxicity of the amyloid ADan peptide implicated in familial Danish dementia G Gibson, N Gunasekera, M Lee, V Lelyveld, OMA El‐Agnaf, A Wright, ... Journal of neurochemistry 88 (2), 281-290, 2004 | 54 | 2004 |
| Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA SC Kim, DK O’Flaherty, L Zhou, VS Lelyveld, JW Szostak Proceedings of the National Academy of Sciences 115 (52), 13318-13323, 2018 | 48 | 2018 |
| Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin EM Brustad, VS Lelyveld, CD Snow, N Crook, ST Jung, FM Martinez, ... Journal of molecular biology 422 (2), 245-262, 2012 | 46 | 2012 |
| Molecular fMRI of serotonin transport A Hai, LX Cai, T Lee, VS Lelyveld, A Jasanoff Neuron 92 (4), 754-765, 2016 | 41 | 2016 |
| Bidirectional direct sequencing of noncanonical RNA by two-dimensional analysis of mass chromatograms A Björkbom, VS Lelyveld, S Zhang, W Zhang, CP Tam, JC Blain, ... Journal of the American Chemical Society 137 (45), 14430-14438, 2015 | 28 | 2015 |
| Challenges for molecular neuroimaging with MRI VS Lelyveld, T Atanasijevic, A Jasanoff International journal of imaging systems and technology 20 (1), 71-79, 2010 | 28 | 2010 |
| Experimental and computational evidence for a loose transition state in phosphoroimidazolide hydrolysis L Li, VS Lelyveld, N Prywes, JW Szostak Journal of the American Chemical Society 138 (12), 3986-3989, 2016 | 18 | 2016 |
| Pinpointing RNA-protein cross-links with site-specific stable isotope-labeled oligonucleotides VS Lelyveld, A Björkbom, EM Ransey, P Sliz, JW Szostak Journal of the American Chemical Society 137 (49), 15378-15381, 2015 | 17 | 2015 |
| Properties of neurotoxic peptides related to the BRI gene B Austen, O EI-Agnaf, S Nagala, B Patel, N Gunasekera, M Lee, ... Biochemical Society Transactions 30 (4), 557-559, 2002 | 14 | 2002 |
| Magnetic nanosensors optimized for rapid and reversible self-assembly E Rodriguez, VS Lelyveld, T Atanasijevic, S Okada, A Jasanoff Chemical communications 50 (27), 3595-3598, 2014 | 13 | 2014 |
| Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization W Zhang, SC Kim, CP Tam, VS Lelyveld, S Bala, JC Chaput, JW Szostak Nucleic acids research 49 (2), 646-656, 2021 | 12 | 2021 |
| DNA polymerase activity on synthetic N3′→ P5′ phosphoramidate DNA templates VS Lelyveld, DK O’Flaherty, L Zhou, EC Izgu, JW Szostak Nucleic acids research 47 (17), 8941-8949, 2019 | 9 | 2019 |
| Comparative analysis of LIN28-RNA binding sites identified at single nucleotide resolution E Ransey, A Björkbom, VS Lelyveld, P Biecek, L Pantano, JW Szostak, ... RNA biology 14 (12), 1756-1765, 2017 | 9 | 2017 |
| Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase VS Lelyveld, W Zhang, JW Szostak Proceedings of the National Academy of Sciences 117 (13), 7276-7283, 2020 | 7 | 2020 |
Jack W. SzostakMassachusetts General Hospital, Harvard, HHMIVerified email at molbio.mgh.harvard.edu
