| β-Lactones as specific inhibitors of ClpP attenuate the production of extracellular virulence factors of Staphylococcus aureus T Böttcher, SA Sieber Journal of the American Chemical Society 130 (44), 14400-14401, 2008 | 226 | 2008 |
| Natural products and their biological targets: proteomic and metabolomic labeling strategies T Böttcher, M Pitscheider, SA Sieber Angewandte Chemie International Edition 49 (15), 2680-2698, 2010 | 212 | 2010 |
| β‐Lactones as Privileged Structures for the Active‐Site Labeling of Versatile Bacterial Enzyme Classes T Böttcher, SA Sieber Angewandte Chemie International Edition 47 (24), 4600-4603, 2008 | 197 | 2008 |
| Synthesis and activity of biomimetic biofilm disruptors T Böttcher, I Kolodkin-Gal, R Kolter, R Losick, J Clardy Journal of the American Chemical Society 135 (8), 2927-2930, 2013 | 160 | 2013 |
| Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras‐Signaling Modulators Palmostatin B and M M Rusch, TJ Zimmermann, M Bürger, FJ Dekker, K Görmer, G Triola, ... Angewandte Chemie International Edition 50 (42), 9838-9842, 2011 | 133 | 2011 |
| An Additive Definition of Molecular Complexity T Böttcher Journal of chemical information and modeling 56 (3), 462-470, 2016 | 113 | 2016 |
| Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria T Böttcher, SA Sieber Journal of the American Chemical Society 132 (20), 6964-6972, 2010 | 110 | 2010 |
| Phenyl esters are potent inhibitors of caseinolytic protease p and reveal a stereogenic switch for deoligomerization MW Hackl, M Lakemeyer, M Dahmen, M Glaser, A Pahl, K Lorenz-Baath, ... Journal of the American Chemical Society 137 (26), 8475-8483, 2015 | 102 | 2015 |
| β-Lactams and β-lactones as activity-based probes in chemical biology T Böttcher, SA Sieber MedChemComm 3 (4), 408-417, 2012 | 98 | 2012 |
| Vibralactone as a tool to study the activity and structure of the ClpP1P2 complex from Listeria monocytogenes E Zeiler, N Braun, T Böttcher, A Kastenmüller, S Weinkauf, SA Sieber Angewandte Chemie International Edition 50 (46), 11001-11004, 2011 | 95 | 2011 |
| A conformational switch underlies ClpP protease function SR Geiger, T Böttcher, SA Sieber, P Cramer Angewandte Chemie International Edition 50 (25), 5749-5752, 2011 | 79 | 2011 |
| Structurally Refined β‐Lactones as Potent Inhibitors of Devastating Bacterial Virulence Factors T Böttcher, SA Sieber Chembiochem 10 (4), 663-666, 2009 | 76 | 2009 |
| The mechanism of caseinolytic protease (ClpP) inhibition M Gersch, F Gut, VS Korotkov, J Lehmann, T Böttcher, M Rusch, ... Angewandte Chemie International Edition 52 (10), 3009-3014, 2013 | 67 | 2013 |
| A cyanobacterial serine protease of Plasmodium falciparum is targeted to the apicoplast and plays an important role in its growth and development S Rathore, D Sinha, M Asad, T Böttcher, F Afrin, VS Chauhan, D Gupta, ... Molecular microbiology 77 (4), 873-890, 2010 | 64 | 2010 |
| A chimeric siderophore halts swarming vibrio T Böttcher, J Clardy Angewandte Chemie International Edition 53 (13), 3510-3513, 2014 | 61 | 2014 |
| Development and characterization of improved β-lactone-based anti-virulence drugs targeting ClpP E Zeiler, VS Korotkov, K Lorenz-Baath, T Böttcher, SA Sieber Bioorganic & medicinal chemistry 20 (2), 583-591, 2012 | 61 | 2012 |
| Inhibitors of Bacterial Swarming Behavior S Rütschlin, T Böttcher Chemistry–A European Journal 26 (5), 964-979, 2020 | 59 | 2020 |
| An Unsaturated Quinolone N‐Oxide of Pseudomonas aeruginosa Modulates Growth and Virulence of Staphylococcus aureus D Szamosvári, T Böttcher Angewandte Chemie International Edition 56 (25), 7271-7275, 2017 | 57 | 2017 |
| A β‐Lactone‐Based Antivirulence Drug Ameliorates Staphylococcus aureus Skin Infections in Mice F Weinandy, K Lorenz‐Baath, VS Korotkov, T Böttcher, S Sethi, ... ChemMedChem 9 (4), 710-713, 2014 | 46 | 2014 |
| β‐Lactones Decrease the Intracellular Virulence of Listeria monocytogenes in Macrophages T Böttcher, SA Sieber ChemMedChem 4 (8), 1260-1263, 2009 | 45 | 2009 |
Sumit rathoreAssociate Professor All India Institute of Medical SciencesBestätigte E-Mail-Adresse bei aiims.edu
