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Thomas Böttcher
Thomas Böttcher
Bestätigte E-Mail-Adresse bei univie.ac.at - Startseite
Titel
Zitiert von
Zitiert von
Jahr
β-Lactones as specific inhibitors of ClpP attenuate the production of extracellular virulence factors of Staphylococcus aureus
T Böttcher, SA Sieber
Journal of the American Chemical Society 130 (44), 14400-14401, 2008
2272008
Natural products and their biological targets: proteomic and metabolomic labeling strategies
T Böttcher, M Pitscheider, SA Sieber
Angewandte Chemie International Edition 49 (15), 2680-2698, 2010
2142010
β‐Lactones as Privileged Structures for the Active‐Site Labeling of Versatile Bacterial Enzyme Classes
T Böttcher, SA Sieber
Angewandte Chemie International Edition 47 (24), 4600-4603, 2008
1972008
Synthesis and activity of biomimetic biofilm disruptors
T Böttcher, I Kolodkin-Gal, R Kolter, R Losick, J Clardy
Journal of the American Chemical Society 135 (8), 2927-2930, 2013
1612013
Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras‐Signaling Modulators Palmostatin B and M
M Rusch, TJ Zimmermann, M Bürger, FJ Dekker, K Görmer, G Triola, ...
Angewandte Chemie International Edition 50 (42), 9838-9842, 2011
1362011
An Additive Definition of Molecular Complexity
T Böttcher
Journal of chemical information and modeling 56 (3), 462-470, 2016
1162016
Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria
T Böttcher, SA Sieber
Journal of the American Chemical Society 132 (20), 6964-6972, 2010
1112010
Phenyl esters are potent inhibitors of caseinolytic protease p and reveal a stereogenic switch for deoligomerization
MW Hackl, M Lakemeyer, M Dahmen, M Glaser, A Pahl, K Lorenz-Baath, ...
Journal of the American Chemical Society 137 (26), 8475-8483, 2015
1032015
β-Lactams and β-lactones as activity-based probes in chemical biology
T Böttcher, SA Sieber
MedChemComm 3 (4), 408-417, 2012
982012
Vibralactone as a tool to study the activity and structure of the ClpP1P2 complex from Listeria monocytogenes
E Zeiler, N Braun, T Böttcher, A Kastenmüller, S Weinkauf, SA Sieber
Angewandte Chemie International Edition 50 (46), 11001-11004, 2011
952011
A conformational switch underlies ClpP protease function
SR Geiger, T Böttcher, SA Sieber, P Cramer
Angewandte Chemie International Edition 50 (25), 5749-5752, 2011
792011
Structurally Refined β‐Lactones as Potent Inhibitors of Devastating Bacterial Virulence Factors
T Böttcher, SA Sieber
Chembiochem 10 (4), 663-666, 2009
762009
The mechanism of caseinolytic protease (ClpP) inhibition
M Gersch, F Gut, VS Korotkov, J Lehmann, T Böttcher, M Rusch, ...
Angewandte Chemie International Edition 52 (10), 3009-3014, 2013
672013
A cyanobacterial serine protease of Plasmodium falciparum is targeted to the apicoplast and plays an important role in its growth and development
S Rathore, D Sinha, M Asad, T Böttcher, F Afrin, VS Chauhan, D Gupta, ...
Molecular microbiology 77 (4), 873-890, 2010
642010
Inhibitors of Bacterial Swarming Behavior
S Rütschlin, T Böttcher
Chemistry–A European Journal 26 (5), 964-979, 2020
632020
A chimeric siderophore halts swarming vibrio
T Böttcher, J Clardy
Angewandte Chemie International Edition 53 (13), 3510-3513, 2014
622014
Development and characterization of improved β-lactone-based anti-virulence drugs targeting ClpP
E Zeiler, VS Korotkov, K Lorenz-Baath, T Böttcher, SA Sieber
Bioorganic & medicinal chemistry 20 (2), 583-591, 2012
612012
An Unsaturated Quinolone N‐Oxide of Pseudomonas aeruginosa Modulates Growth and Virulence of Staphylococcus aureus
D Szamosvári, T Böttcher
Angewandte Chemie International Edition 56 (25), 7271-7275, 2017
572017
A β‐Lactone‐Based Antivirulence Drug Ameliorates Staphylococcus aureus Skin Infections in Mice
F Weinandy, K Lorenz‐Baath, VS Korotkov, T Böttcher, S Sethi, ...
ChemMedChem 9 (4), 710-713, 2014
462014
β‐Lactones Decrease the Intracellular Virulence of Listeria monocytogenes in Macrophages
T Böttcher, SA Sieber
ChemMedChem 4 (8), 1260-1263, 2009
452009
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