| Reactive oxygen species, antioxidants, and the mammalian thioredoxin system J Nordberg, ESJ Arnér Free radical biology and medicine 31 (11), 1287-1312, 2001 | 3983 | 2001 |
| Physiological functions of thioredoxin and thioredoxin reductase ESJ Arnér, A Holmgren European journal of biochemistry 267 (20), 6102-6109, 2000 | 3208 | 2000 |
| Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis I Ingold, C Berndt, S Schmitt, S Doll, G Poschmann, K Buday, A Roveri, ... Cell 172 (3), 409-422. e21, 2018 | 1049 | 2018 |
| Mammalian deoxyribonucleoside kinases ESJ Arnér, S Eriksson Pharmacology & therapeutics 67 (2), 155-186, 1995 | 775 | 1995 |
| Focus on mammalian thioredoxin reductases—important selenoproteins with versatile functions ESJ Arnér Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (6), 495-526, 2009 | 753 | 2009 |
| The thioredoxin system in cancer ESJ Arner, A Holmgren Seminars in cancer biology 16 (6), 420-426, 2006 | 662 | 2006 |
| Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine … L Zhong, ESJ Arnér, A Holmgren Proceedings of the National Academy of Sciences 97 (11), 5854-5859, 2000 | 599 | 2000 |
| Selenocysteine in proteins—properties and biotechnological use L Johansson, G Gafvelin, ESJ Arnér Biochimica et Biophysica Acta (BBA)-General Subjects 1726 (1), 1-13, 2005 | 447 | 2005 |
| Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target AN Kuntz, E Davioud-Charvet, AA Sayed, LL Califf, J Dessolin, ESJ Arnér, ... PLoS medicine 4 (6), e206, 2007 | 422 | 2007 |
| Preparation and assay of mammalian thioredoxin and thioredoxin reductase ESJ Arnér, L Zhong, A Holmgren Methods in enzymology 300, 226-239, 1999 | 376 | 1999 |
| Paradoxical roles of antioxidant enzymes: basic mechanisms and health implications XG Lei, JH Zhu, WH Cheng, Y Bao, YS Ho, AR Reddi, A Holmgren, ... Physiological reviews 96 (1), 307-364, 2016 | 366 | 2016 |
| Selenoproteins—what unique properties can arise with selenocysteine in place of cysteine? ESJ Arnér Experimental cell research 316 (8), 1296-1303, 2010 | 360 | 2010 |
| Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate … L Zhong, ESJ Arnér, J Ljung, F Åslund, A Holmgren Journal of Biological Chemistry 273 (15), 8581-8591, 1998 | 315 | 1998 |
| A novel persulfide detection method reveals protein persulfide-and polysulfide-reducing functions of thioredoxin and glutathione systems É Dóka, I Pader, A Bíró, K Johansson, Q Cheng, K Ballagó, JR Prigge, ... Science advances 2 (1), e1500968, 2016 | 289 | 2016 |
| High-level expression in Escherichia coli of selenocysteine-containing rat thioredoxin reductase utilizing gene fusions with engineered bacterial-type SECIS elements and co … ESJ Arnér, H Sarioglu, F Lottspeich, A Holmgren, A Böck Journal of molecular biology 292 (5), 1003-1016, 1999 | 278 | 1999 |
| The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone: a novel mechanism for defense against oxidative stress L Xia, T Nordman, JM Olsson, A Damdimopoulos, L Björkhem-Bergman, ... Journal of Biological Chemistry 278 (4), 2141-2146, 2003 | 270 | 2003 |
| Selenoprotein gene nomenclature VN Gladyshev, ES Arnér, MJ Berry, R Brigelius-Flohé, EA Bruford, ... Journal of Biological Chemistry 291 (46), 24036-24040, 2016 | 253 | 2016 |
| Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events AK Rundlöf, ESJ Arnér Antioxidants and Redox Signaling 6 (1), 41-52, 2004 | 248 | 2004 |
| Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds AB Witte, K Anestål, E Jerremalm, H Ehrsson, ESJ Arnér Free Radical Biology and Medicine 39 (5), 696-703, 2005 | 242 | 2005 |
| Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue J Nordberg, L Zhong, A Holmgren, ESJ Arnér Journal of Biological Chemistry 273 (18), 10835-10842, 1998 | 242 | 1998 |
