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Sowmya Iyer
Sowmya Iyer
Director, Data Science and Computational Biology
Bestätigte E-Mail-Adresse bei bu.edu
Titel
Zitiert von
Zitiert von
Jahr
An integrated encyclopedia of DNA elements in the human genome. vol. 489
I Dunham, A Kundaje, SF Aldred, PJ Collins, CA Davis, F Doyle, ...
Nature, 57-74, 2012
3044*2012
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
J Wang, J Zhuang, S Iyer, XY Lin, TW Whitfield, MC Greven, BG Pierce, ...
Genome research 22 (9), 1798-1812, 2012
10432012
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung
Nature 569 (7756), 433-437, 2019
5212019
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ...
Nature 593 (7859), 429-434, 2021
4632021
Factorbook. org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium
J Wang, J Zhuang, S Iyer, XY Lin, MC Greven, BH Kim, J Moore, ...
Nucleic acids research 41 (D1), D171-D176, 2012
4302012
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
IC Kurt, R Zhou, S Iyer, SP Garcia, BR Miller, LM Langner, J Grünewald, ...
Nature biotechnology 39 (1), 41-46, 2021
4012021
Cancer-specific retargeting of BAF complexes by a prion-like domain
G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ...
Cell 171 (1), 163-178. e19, 2017
3812017
CRISPR DNA base editors with reduced RNA off-target and self-editing activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
Nature biotechnology 37 (9), 1041-1048, 2019
2672019
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ...
Nature biotechnology 38 (7), 861-864, 2020
2142020
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
Q Tang, S Iyer, R Lobbardi, JC Moore, H Chen, C Lareau, C Hebert, ...
Journal of Experimental Medicine 214 (10), 2875-2887, 2017
1482017
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ...
Cell 182 (6), 1474-1489. e23, 2020
1362020
Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ...
Cell stem cell 22 (3), 414-427. e6, 2018
662018
Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies
G Boulay, A Volorio, S Iyer, LC Broye, I Stamenkovic, N Riggi, MN Rivera
Genes & development 32 (15-16), 1008-1019, 2018
652018
The macrophage‐expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish
G Ferrero, E Gomez, S Lyer, M Rovira, M Miserocchi, DM Langenau, ...
Journal of leukocyte biology 107 (3), 431-443, 2020
632020
OTX2 activity at distal regulatory elements shapes the chromatin landscape of group 3 medulloblastoma
G Boulay, ME Awad, N Riggi, TC Archer, S Iyer, WE Boonseng, ...
Cancer discovery 7 (3), 288-301, 2017
572017
Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia
EG Garcia, S Iyer, SP Garcia, S Loontiens, RI Sadreyev, F Speleman, ...
Leukemia 32 (8), 1860-1865, 2018
282018
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
W Giblin, L Bringman-Rodenbarger, AH Guo, S Kumar, AC Monovich, ...
The Journal of Clinical Investigation, 2021
262021
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 31 (2), 2020
252020
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 30 (13), 4567-4583. e5, 2020
252020
High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody
GJ Babcock, S Iyer, HL Smith, Y Wang, K Rowley, DM Ambrosino, ...
PloS one 9 (6), e100325, 2014
222014
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