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Sowmya Iyer
Sowmya Iyer
Director, Data Science and Computational Biology
Verified email at bu.edu
Title
Cited by
Cited by
Year
An integrated encyclopedia of DNA elements in the human genome. vol. 489
I Dunham, A Kundaje, SF Aldred, PJ Collins, CA Davis, F Doyle, ...
Nature, 57-74, 2012
3060*2012
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
J Wang, J Zhuang, S Iyer, XY Lin, TW Whitfield, MC Greven, BG Pierce, ...
Genome research 22 (9), 1798-1812, 2012
10452012
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung
Nature 569 (7756), 433-437, 2019
5272019
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ...
Nature 593 (7859), 429-434, 2021
4742021
Factorbook. org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium
J Wang, J Zhuang, S Iyer, XY Lin, MC Greven, BH Kim, J Moore, ...
Nucleic acids research 41 (D1), D171-D176, 2012
4312012
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
IC Kurt, R Zhou, S Iyer, SP Garcia, BR Miller, LM Langner, J Grünewald, ...
Nature biotechnology 39 (1), 41-46, 2021
4082021
Cancer-specific retargeting of BAF complexes by a prion-like domain
G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ...
Cell 171 (1), 163-178. e19, 2017
3852017
CRISPR DNA base editors with reduced RNA off-target and self-editing activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
Nature biotechnology 37 (9), 1041-1048, 2019
2682019
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ...
Nature biotechnology 38 (7), 861-864, 2020
2162020
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
Q Tang, S Iyer, R Lobbardi, JC Moore, H Chen, C Lareau, C Hebert, ...
Journal of Experimental Medicine 214 (10), 2875-2887, 2017
1522017
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ...
Cell 182 (6), 1474-1489. e23, 2020
1392020
Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies
G Boulay, A Volorio, S Iyer, LC Broye, I Stamenkovic, N Riggi, MN Rivera
Genes & development 32 (15-16), 1008-1019, 2018
672018
Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ...
Cell stem cell 22 (3), 414-427. e6, 2018
662018
The macrophage‐expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish
G Ferrero, E Gomez, S Lyer, M Rovira, M Miserocchi, DM Langenau, ...
Journal of leukocyte biology 107 (3), 431-443, 2020
642020
OTX2 activity at distal regulatory elements shapes the chromatin landscape of group 3 medulloblastoma
G Boulay, ME Awad, N Riggi, TC Archer, S Iyer, WE Boonseng, ...
Cancer discovery 7 (3), 288-301, 2017
572017
Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia
EG Garcia, S Iyer, SP Garcia, S Loontiens, RI Sadreyev, F Speleman, ...
Leukemia 32 (8), 1860-1865, 2018
282018
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
W Giblin, L Bringman-Rodenbarger, AH Guo, S Kumar, AC Monovich, ...
The Journal of Clinical Investigation, 2021
272021
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 31 (2), 2020
272020
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 30 (13), 4567-4583. e5, 2020
272020
High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody
GJ Babcock, S Iyer, HL Smith, Y Wang, K Rowley, DM Ambrosino, ...
PloS one 9 (6), e100325, 2014
222014
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