Regulation of glucose metabolism–a perspective from cell bioprocessing BC Mulukutla, A Yongky, T Le, DG Mashek, WS Hu Trends in biotechnology 34 (8), 638-651, 2016 | 144 | 2016 |
Single copy transgene integration in a transcriptionally active site for recombinant protein synthesis SA O'Brien, K Lee, HY Fu, Z Lee, TS Le, CS Stach, MG McCann, ... Biotechnology journal 13 (10), 1800226, 2018 | 39 | 2018 |
Advancing biopharmaceutical process science through transcriptome analysis N Vishwanathan, H Le, T Le, WS Hu Current opinion in biotechnology 30, 113-119, 2014 | 32 | 2014 |
Mechanism for multiplicity of steady states with distinct cell concentration in continuous culture of mammalian cells A Yongky, J Lee, T Le, BC Mulukutla, P Daoutidis, WS Hu Biotechnology and bioengineering 112 (7), 1437-1445, 2015 | 23 | 2015 |
Model-driven engineering of N-linked glycosylation in Chinese hamster ovary cells CS Stach, MG McCann, CM O’Brien, TS Le, N Somia, X Chen, K Lee, ... ACS synthetic biology 8 (11), 2524-2535, 2019 | 19 | 2019 |
Automated network generation and analysis of biochemical reaction pathways using RING U Gupta, T Le, WS Hu, A Bhan, P Daoutidis Metabolic engineering 49, 84-93, 2018 | 15 | 2018 |
An introduction to mammalian cell culture TS Le, M McCann, SM Azarin, WS Hu Chem Eng Prog 112 (4), 34-40, 2016 | 10 | 2016 |
An integrated platform for mucintype Oglycosylation network generation and visualization T Le, C O’Brien, U Gupta, G Sousa, P Daoutidis, WS Hu Biotechnology and bioengineering 116 (6), 1341-1354, 2019 | 7 | 2019 |
Steering N-glycosylation of recombinant proteins using systems engineering M McCann, T Le, C Stach, X Chen, N Somia, L Zhao, M Smanski, WS Hu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
Systems Analysis in Mammalian Cell Biomanufacturing-Linking Energy Metabolism and Glycosylation TS Le University of Minnesota, 2018 | | 2018 |
A synthetic biology based cell line engineering pipeline WS Hu, CS Stach, S O’Brien, A Bandyopadhyay, M McCann, C O’Brien, ... | | 2018 |
Systems engineering N-glycans of recombinant therapeutic proteins MG McCann, CS Stach, T Le, N Somia, M Smanski, WS Hu, X Chen, ... | | 2018 |
Systems engineering of N-glycans for the production of recombinant proteins in mammalian cells T Le, C Stach, M McCann, S O'Brien, X Chen, L Zhao, M Smanski, WS Hu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
On the shift-up to high lactate production in fed-batch culture of mammalian cells T Le, C O'Brien, T Phan, E Liu, WS Hu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Systems engineering of a CHO cell line for enhanced process robustness K Lee, HY Fu, L Zhao, L Feng, T Le, H Pei, S Rajput, D Cho, N Somia, ... | | 2016 |
Unraveling the effect of energy metabolism on N-glycosylation of recombinant protein produced in mammalian cells T Le, A Yongky, S Grimm, WS Hu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |
Bridging transcriptomics, modeling and process control in a systems approach for mammalian cell culture V Konakovsky, T Le, A Yongky, R Raju, N Vishvanathan, C Herwig, ... Proceedings, 142-147, 2015 | | 2015 |
Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, USA A Yongky, J Lee, T Le, BC Mulukutla, P Daoutidis, WS Hu | | |