The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism X Zheng, NB Rumie Vittar, X Gai, MG Fernandez-Barrena, CD Moser, ... PloS one 7 (11), e49581, 2012 | 94 | 2012 |
Effect of ω-3 and ω-9 fatty acid rich oils on lipoxygenases and cyclooxygenases enzymes and on the growth of a mammary adenocarcinoma model A Comba, DM Maestri, MA Berra, CP Garcia, UN Das, AR Eynard, ... Lipids in Health and Disease 9, 1-11, 2010 | 85 | 2010 |
Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors A Comba, YH Lin, AR Eynard, MA Valentich, ME Fernandez-Zapico, ... Cancer and Metastasis Reviews 30, 325-342, 2011 | 60 | 2011 |
Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis S Rizvi, CJ DeMars, A Comba, VG Gainullin, Z Rizvi, LL Almada, K Wang, ... Cancer research 70 (17), 6787-6796, 2010 | 52 | 2010 |
Systemic delivery of an adjuvant CXCR4–CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy MS Alghamri, K Banerjee, AA Mujeeb, A Mauser, A Taher, R Thalla, ... ACS nano 16 (6), 8729-8750, 2022 | 48 | 2022 |
Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis M Vara-Messler, ME Pasqualini, A Comba, R Silva, C Buccellati, A Trenti, ... European journal of nutrition 56, 509-519, 2017 | 43 | 2017 |
Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses A Comba, PJ Dunn, AE Argento, P Kadiyala, M Ventosa, P Patel, ... Neuro-oncology 22 (6), 806-818, 2020 | 41 | 2020 |
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression A Comba, SM Faisal, PJ Dunn, AE Argento, TC Hollon, WN Al-Holou, ... Nature communications 13 (1), 3606, 2022 | 36 | 2022 |
Uncovering spatiotemporal heterogeneity of high-grade gliomas: From disease biology to therapeutic implications A Comba, SM Faisal, ML Varela, T Hollon, WN Al-Holou, Y Umemura, ... Frontiers in oncology 11, 703764, 2021 | 36 | 2021 |
Synergistic anti-tumor effects of melatonin and PUFAs from walnuts in a murine mammary adenocarcinoma model CP Garcia, AL Lamarque, A Comba, MA Berra, RA Silva, DO Labuckas, ... Nutrition 31 (4), 570-577, 2015 | 35 | 2015 |
H3. 3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models S Haase, K Banerjee, AA Mujeeb, CS Hartlage, FM Núñez, FJ Núñez, ... The Journal of Clinical Investigation 132 (22), 2022 | 31 | 2022 |
Primers on molecular pathways—lipoxygenases: their role as an oncogenic pathway in pancreatic cancer A Comba, ME Pasqualini Pancreatology 9 (6), 724-728, 2009 | 28 | 2009 |
Self-organization in brain tumors: How cell morphology and cell density influence glioma pattern formation S Jamous, A Comba, PR Lowenstein, S Motsch PLoS computational biology 16 (5), e1007611, 2020 | 24 | 2020 |
Arginylated calreticulin increases apoptotic response induced by bortezomib in glioma cells A Comba, LV Bonnet, VE Goitea, ME Hallak, MR Galiano Molecular Neurobiology 56, 1653-1664, 2019 | 19 | 2019 |
Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development MB Garcia-Fabiani, M Ventosa, A Comba, M Candolfi, AJ Nicola Candia, ... Expert Opinion on Investigational Drugs 29 (7), 659-684, 2020 | 17 | 2020 |
The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications SM Faisal, A Comba, ML Varela, AE Argento, E Brumley, C Abel, ... Frontiers in Oncology 12, 1005069, 2022 | 16 | 2022 |
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1 D Shah, A Comba, SM Faisal, P Kadiyala, GJ Baker, MS Alghamri, ... Oncoimmunology 10 (1), 1939601, 2021 | 16 | 2021 |
Nuclear factor of activated T cells-dependent down-regulation of the transcription factor glioma-associated protein 1 (GLI1) underlies the growth inhibitory properties of … A Comba, LL Almada, EJ Tolosa, E Iguchi, DL Marks, MV Messler, R Silva, ... Journal of Biological Chemistry 291 (4), 1933-1947, 2016 | 15 | 2016 |
Genetic alterations in gliomas remodel the tumor immune microenvironment and impact immune-mediated therapies MB Garcia-Fabiani, S Haase, A Comba, S Carney, B McClellan, ... Frontiers in Oncology 11, 631037, 2021 | 13 | 2021 |
First-in-human phase I trial of the combination of two adenoviral vectors expressing HSV1-TK and FLT3L for the treatment of newly diagnosed resectable malignant glioma: Initial … PR Lowenstein, DA Orringer, O Sagher, J Heth, SL Hervey-Jumper, ... Journal of Clinical Oncology 37 (15_suppl), 2019-2019, 2019 | 12 | 2019 |