Fred Schaper
Fred Schaper
Professor of Systems Biology, Otto-von-Guericke University Magdeburg
Bestätigte E-Mail-Adresse bei ovgu.de - Startseite
TitelZitiert vonJahr
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
PC Heinrich, I Behrmann, S Haan, HM Hermanns, G Müller-Newen, ...
Biochemical journal 374 (1), 1-20, 2003
31582003
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
PC Heinrich, I Behrmann, G Müller-Newen, F Schaper, L Graeve
Biochemical journal 334 (2), 297-314, 1998
23571998
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
J Schmitz, M Weissenbach, S Haan, PC Heinrich, F Schaper
Journal of Biological Chemistry 275 (17), 12848-12856, 2000
4652000
IFN-α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3
JG Bode, S Ludwig, C Ehrhardt, UTE ALBRECHT, A ERHARDT, ...
The FASEB Journal 17 (3), 488-490, 2003
3732003
Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
C Niemand, A Nimmesgern, S Haan, P Fischer, F Schaper, R Rossaint, ...
The journal of immunology 170 (6), 3263-3272, 2003
3252003
SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130
U Lehmann, J Schmitz, M Weissenbach, RM Sobota, M Hörtner, ...
Journal of Biological Chemistry 278 (1), 661-671, 2003
2812003
Interleukin-6: biology, signaling and strategies of blockade
F Schaper, S Rose-John
Cytokine & growth factor reviews 26 (5), 475-487, 2015
2522015
Hepatic acute phase proteins–regulation by IL-6-and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling
JG Bode, U Albrecht, D Häussinger, PC Heinrich, F Schaper
European journal of cell biology 91 (6-7), 496-505, 2012
2492012
LPS and TNFα induce SOCS3 mRNA and inhibit IL‐6‐induced activation of STAT3 in macrophages
JG Bode, A Nimmesgern, J Schmitz, F Schaper, M Schmitt, W Frisch, ...
FEBS letters 463 (3), 365-370, 1999
2221999
Plasticity and cross-talk of interleukin 6-type cytokines
C Garbers, HM Hermanns, F Schaper, G Müller-Newen, J Grötzinger, ...
Cytokine & growth factor reviews 23 (3), 85-97, 2012
2192012
Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein …
F SCHAPER, C GENDO, ECK Monika, J SCHMITZ, C GRIMM, D ANHUF, ...
Biochemical journal 335 (3), 557-565, 1998
2091998
Expression of suppressors of cytokine signaling during liver regeneration
JS Campbell, L Prichard, F Schaper, J Schmitz, A Stephenson-Famy, ...
The Journal of clinical investigation 107 (10), 1285-1292, 2001
1862001
Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA
R Sharf, D Meraro, A Azriel, AM Thornton, K Ozato, EF Petricoin, ...
Journal of Biological Chemistry 272 (15), 9785-9792, 1997
1731997
Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes
S Kirchhoff, F Schaper, H Hauser
Nucleic acids research 21 (12), 2881-2889, 1993
1601993
The zinc finger protein Gfi‐1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3
B Rödel, K Tavassoli, H Karsunky, T Schmidt, M Bachmann, F Schaper, ...
The EMBO Journal 19 (21), 5845-5855, 2000
1442000
Different protein turnover of interleukin‐6‐type cytokine signalling components
E Siewert, W Müller‐Esterl, R Starr, PC Heinrich, F Schaper
European journal of biochemistry 265 (1), 251-257, 1999
1301999
IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR.
S Kirchhoff, AE Koromilas, F Schaper, M Grashoff, N Sonenberg, ...
Oncogene 11 (3), 439-445, 1995
1281995
Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-α involves activation of the MKK6/p38MAPK/MK2 cascade
C Ehlting, WS Lai, F Schaper, ED Brenndörfer, RJ Matthes, PC Heinrich, ...
The Journal of Immunology 178 (5), 2813-2826, 2007
1232007
Interleukin-6 signalling: more than Jaks and STATs
R Eulenfeld, A Dittrich, C Khouri, PJ Müller, B Mütze, A Wolf, F Schaper
European journal of cell biology 91 (6-7), 486-495, 2012
1212012
Functional domains of interferon regulatory factor I (IRF-1)
F SCHAPER, S KIRCHHOFF, G POSERN, M KÖSTER, A OUMARD, ...
Biochemical Journal 335 (1), 147-157, 1998
971998
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