Rameshwar U. Kadam, Ph.D
Rameshwar U. Kadam, Ph.D
Senior Research Associate, The Scripps Research Institute
Verified email at - Homepage
Cited by
Cited by
Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol
RU Kadam, IA Wilson
Proceedings of the National Academy of Sciences 114 (2), 206-214, 2017
Hepatitis C virus E2 envelope glycoprotein core structure
L Kong, E Giang, T Nieusma, RU Kadam, KE Cogburn, Y Hua, X Dai, ...
Science 342 (6162), 1090-1094, 2013
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB
EMV Johansson, SA Crusz, E Kolomiets, L Buts, RU Kadam, M Cacciarini, ...
Chemistry & biology 15 (12), 1249-1257, 2008
Design of protein-binding proteins from the target structure alone
L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ...
Nature 605 (7910), 551-560, 2022
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms
RU Kadam, M Bergmann, M Hurley, D Garg, M Cacciarini, MA Swiderska, ...
Angewandte Chemie (International ed. in English) 50 (45), 10631, 2011
Potent peptidic fusion inhibitors of influenza virus
RU Kadam, J Juraszek, B Brandenburg, C Buyck, WBG Schepens, ...
Science 358 (6362), 496-502, 2017
Recent trends in drug-likeness prediction: a comprehensive review of in silico methods
R Kadam, N Roy
Indian Journal of Pharmaceutical Sciences 69 (5), 609, 2007
A small-molecule fusion inhibitor of influenza virus is orally active in mice
MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ...
Science 363 (6431), eaar6221, 2019
CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA
RU Kadam, D Garg, J Schwartz, R Visini, M Sattler, A Stocker, T Darbre, ...
ACS chemical biology 8 (9), 1925-1930, 2013
Glycopeptide Dendrimers with High Affinity for the Fucose‐Binding Lectin LecB from Pseudomonas aeruginosa
E Kolomiets, MA Swiderska, RU Kadam, EMV Johansson, KE Jaeger, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 562-569, 2009
Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen
L Kong, DE Lee, RU Kadam, T Liu, E Giang, T Nieusma, F Garces, ...
Proceedings of the National Academy of Sciences 113 (45), 12768-12773, 2016
Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility
NC Wu, H Lv, AJ Thompson, DC Wu, WWS Ng, RU Kadam, CW Lin, ...
Cell host & microbe 25 (6), 836-844. e5, 2019
Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin
ZVF Wright, NC Wu, RU Kadam, IA Wilson, DW Wolan
Bioorganic & medicinal chemistry letters 27 (16), 3744-3748, 2017
Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids
E Johansson, RU Kadam
MedChemComm 2 (5), 418-420, 2011
Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314–324 in complex with antibody IGH526
L Kong, RU Kadam, E Giang, TB Ruwona, T Nieusma, JC Culhane, ...
Journal of molecular biology 427 (16), 2617-2628, 2015
Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini
M Stach, N Maillard, RU Kadam
MedChemComm 3 (1), 86-89, 2012
Structure‐Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA
RU Kadam, M Bergmann, D Garg, G Gabrieli, A Stocker, T Darbre, ...
Chemistry–A European Journal 19 (50), 17054-17063, 2013
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen
Y Yao, RU Kadam, CCD Lee, JL Woehl, NC Wu, X Zhu, S Kitamura, ...
Proceedings of the National Academy of Sciences 117 (31), 18431-18438, 2020
A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin
RU Kadam, IA Wilson
Proceedings of the National Academy of Sciences 115 (16), 4240-4245, 2018
Cluster analysis and two-dimensional quantitative structure–activity relationship (2D-QSAR) of Pseudomonas aeruginosa deacetylase LpxC inhibitors
RU Kadam, N Roy
Bioorganic & medicinal chemistry letters 16 (19), 5136-5143, 2006
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