Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels C Ko, A Chakraborty, WM Chou, J Hasreiter, JM Wettengel, D Stadler, ... Journal of hepatology 69 (6), 1231-1241, 2018 | 216 | 2018 |
DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level C Ko, S Lee, MP Windisch, WS Ryu Journal of virology 88 (23), 13689-13698, 2014 | 93 | 2014 |
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques BJ Burwitz, JM Wettengel, MA Mück-Häusl, M Ringelhan, C Ko, ... Nature communications 8 (1), 2146, 2017 | 76 | 2017 |
The FDA-approved drug irbesartan inhibits HBV-infection in HepG2 cells stably expressing sodium taurocholate co-transporting polypeptide C Ko, WJ Park, S Park, S Kim, MP Windisch, WS Ryu Antiviral therapy 20 (8), 835-842, 2015 | 71 | 2015 |
Hepatitis B virus X protein enhances Myc stability by inhibiting SCFSkp2 ubiquitin E3 ligase-mediated Myc ubiquitination and contributes to oncogenesis S Lee, W Kim, C Ko, WS Ryu Oncogene 35 (14), 1857-1867, 2016 | 55 | 2016 |
Novel viral and host targets to cure hepatitis B C Ko, T Michler, U Protzer Current opinion in virology 24, 38-45, 2017 | 50 | 2017 |
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread S Ambike, CC Cheng, M Feuerherd, S Velkov, D Baldassi, SQ Afridi, ... Nucleic Acids Research 50 (1), 333-349, 2022 | 49 | 2022 |
Interferon‐induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20 D Stadler, M Kächele, AN Jones, J Hess, C Urban, J Schneider, Y Xia, ... EMBO reports 22 (6), e49568, 2021 | 48 | 2021 |
Analyses of HBV cccDNA quantification and modification Y Xia, D Stadler, C Ko, U Protzer Hepatitis B virus: methods and protocols, 59-72, 2017 | 45 | 2017 |
A new role for capsid assembly modulators to target mature hepatitis B virus capsids and prevent virus infection C Ko, R Bester, X Zhou, Z Xu, C Blossey, J Sacherl, FWR Vondran, L Gao, ... Antimicrobial agents and chemotherapy 64 (1), 10.1128/aac. 01440-19, 2019 | 42 | 2019 |
Comparative analysis of the antiviral effects mediated by type I and III interferons in hepatitis B virus–infected hepatocytes JH Bockmann, D Stadler, Y Xia, C Ko, JM Wettengel, ... The Journal of Infectious Diseases 220 (4), 567-577, 2019 | 33 | 2019 |
DDB1 stimulates viral transcription of hepatitis B virus via HBx-independent mechanisms W Kim, S Lee, Y Son, C Ko, WS Ryu Journal of virology 90 (21), 9644-9653, 2016 | 31 | 2016 |
Residues Arg703, Asp777, and Arg781 of the RNase H domain of hepatitis B virus polymerase are critical for viral DNA synthesis C Ko, YC Shin, WJ Park, S Kim, J Kim, WS Ryu Journal of virology 88 (1), 154-163, 2014 | 30 | 2014 |
Synchronised infection identifies early rate‐limiting steps in the hepatitis B virus life cycle A Chakraborty, C Ko, C Henning, A Lucko, JM Harris, F Chen, X Zhuang, ... Cellular microbiology 22 (12), e13250, 2020 | 26 | 2020 |
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis PAC Wing, T Davenne, J Wettengel, AG Lai, X Zhuang, A Chakraborty, ... Life science alliance 2 (2), 2019 | 26 | 2019 |
TNF-alpha mediated NF-kappaB activation is constantly extended by transglutaminase 2 KS Park, DS Kim, C Ko, SJ Lee, SH Oh, SY Kim Front Biosci (Elite Ed) 3, 341-354, 2011 | 25 | 2011 |
A new regulatory mechanism of NF-κB activation by I-κBβ in cancer cells JM Kim, RE Voll, C Ko, DS Kim, KS Park, SY Kim Journal of molecular biology 384 (4), 756-765, 2008 | 25 | 2008 |
Current progress in the development of hepatitis B virus capsid assembly modulators: chemical structure, mode-of-action and efficacy H Kim, C Ko, JY Lee, M Kim Molecules 26 (24), 7420, 2021 | 21 | 2021 |
Hepatitis B virus promotes β-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion G von Olshausen, M Quasdorff, R Bester, S Arzberger, C Ko, ... Oncotarget 9 (74), 33947, 2018 | 18 | 2018 |
T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice O Quitt, S Luo, M Meyer, Z Xie, F Golsaz-Shirazi, E Loffredo-Verde, ... Journal of hepatology 75 (5), 1058-1071, 2021 | 15 | 2021 |