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Brinda Ravikumar
Brinda Ravikumar
Abbvie
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107332021
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ...
Nature genetics 36 (6), 585-595, 2004
27962004
Regulation of mammalian autophagy in physiology and pathophysiology
B Ravikumar, S Sarkar, JE Davies, M Futter, M Garcia-Arencibia, ...
Physiological reviews 90 (4), 1383-1435, 2010
20792010
α-Synuclein is degraded by both autophagy and the proteasome
JL Webb, B Ravikumar, J Atkins, JN Skepper, DC Rubinsztein
Journal of Biological Chemistry 278 (27), 25009-25013, 2003
17392003
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
B Ravikumar, R Duden, DC Rubinsztein
Human molecular genetics 11 (9), 1107-1117, 2002
13442002
Plasma membrane contributes to the formation of pre-autophagosomal structures
B Ravikumar, K Moreau, L Jahreiss, C Puri, DC Rubinsztein
Nature cell biology 12 (8), 747-757, 2010
11082010
α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
AR Winslow, CW Chen, S Corrochano, A Acevedo-Arozena, DE Gordon, ...
Journal of Cell Biology 190 (6), 1023-1037, 2010
9522010
Rapamycin alleviates toxicity of different aggregate-prone proteins
Z Berger, B Ravikumar, FM Menzies, LG Oroz, BR Underwood, ...
Human molecular genetics 15 (3), 433-442, 2006
8182006
In search of an “autophagomometer”
DC Rubinsztein, AM Cuervo, B Ravikumar, S Sarkar, V Korolchuk, ...
Autophagy 5 (5), 585-589, 2009
6272009
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
S Sarkar, B Ravikumar, RA Floto, DC Rubinsztein
Cell Death & Differentiation 16 (1), 46-56, 2009
6272009
Dynein mutations impair autophagic clearance of aggregate-prone proteins
B Ravikumar, A Acevedo-Arozena, S Imarisio, Z Berger, C Vacher, ...
Nature genetics 37 (7), 771-776, 2005
5542005
Review Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair
DC Rubinsztein, M DiFiglia, N Heintz, RA Nixon, ZH Qin, B Ravikumar, ...
Autophagy 1 (1), 11-22, 2005
5462005
Rapamycin pre-treatment protects against apoptosis
B Ravikumar, Z Berger, C Vacher, CJ O'Kane, DC Rubinsztein
Human molecular genetics 15 (7), 1209-1216, 2006
5152006
Autophagosome precursor maturation requires homotypic fusion
K Moreau, B Ravikumar, M Renna, C Puri, DC Rubinsztein
Cell 146 (2), 303-317, 2011
4202011
Palmitoylation of huntingtin by HIP14is essential for its trafficking and function
A Yanai, K Huang, R Kang, RR Singaraja, P Arstikaitis, L Gan, PC Orban, ...
Nature neuroscience 9 (6), 824-831, 2006
3922006
Aggregate‐Prone Proteins Are Cleared from the Cytosol by Autophagy: Therapeutic Implications
A Williams, L Jahreiss, S Sarkar, S Saiki, FM Menzies, B Ravikumar, ...
Current topics in developmental biology 76, 89-101, 2006
3542006
Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
B Ravikumar, S Imarisio, S Sarkar, CJ O'Kane, DC Rubinsztein
Journal of cell science 121 (10), 1649-1660, 2008
3432008
Mammalian macroautophagy at a glance
B Ravikumar, M Futter, L Jahreiss, VI Korolchuk, M Lichtenberg, S Luo, ...
Journal of cell science 122 (11), 1707-1711, 2009
2482009
Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases
JL Webb, B Ravikumar, DC Rubinsztein
The international journal of biochemistry & cell biology 36 (12), 2541-2550, 2004
2222004
Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy
B Ravikumar, A Stewart, H Kita, K Kato, R Duden, DC Rubinsztein
Human molecular genetics 12 (9), 985-994, 2003
1402003
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