Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila A Akhtar, PB Becker Molecular cell 5 (2), 367-375, 2000 | 536 | 2000 |
The nuclear envelope and transcriptional control A Akhtar, SM Gasser Nature Reviews Genetics 8 (7), 507-517, 2007 | 532 | 2007 |
Chromodomains are protein–RNA interaction modules A Akhtar, D Zink, PB Becker Nature 407 (6802), 405-409, 2000 | 491 | 2000 |
Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila S Mendjan, M Taipale, J Kind, H Holz, P Gebhardt, M Schelder, ... Molecular cell 21 (6), 811-823, 2006 | 433 | 2006 |
High-resolution TADs reveal DNA sequences underlying genome organization in flies F Ramírez, V Bhardwaj, L Arrigoni, KC Lam, BA Grüning, J Villaveces, ... Nature communications 9 (1), 1-15, 2018 | 405 | 2018 |
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome T Aktaş, İ Avşar Ilık, D Maticzka, V Bhardwaj, C Pessoa Rodrigues, ... Nature 544 (7648), 115-119, 2017 | 328 | 2017 |
Science forum: considerations when investigating lncRNA function in vivo AR Bassett, A Akhtar, DP Barlow, AP Bird, N Brockdorff, D Duboule, ... elife 3, e03058, 2014 | 319 | 2014 |
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells M Taipale, S Rea, K Richter, A Vilar, P Lichter, A Imhof, A Akhtar Molecular and cellular biology 25 (15), 6798-6810, 2005 | 316 | 2005 |
Nuclear Pore Proteins Nup153 and Megator Define Transcriptionally Active Regions in the Drosophila Genome JM Vaquerizas, R Suyama, J Kind, K Miura, NM Luscombe, A Akhtar PLoS genetics 6 (2), e1000846, 2010 | 247 | 2010 |
Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription T Conrad, A Akhtar Nature Reviews Genetics 13 (2), 123-134, 2012 | 245 | 2012 |
The dMi-2 chromodomains are DNA binding modules important for ATP-dependent nucleosome mobilization K Bouazoune, A Mitterweger, G Längst, A Imhof, A Akhtar, PB Becker, ... The EMBO journal 21 (10), 2430-2440, 2002 | 203 | 2002 |
Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila J Kind, JM Vaquerizas, P Gebhardt, M Gentzel, NM Luscombe, P Bertone, ... cell 133 (5), 813-828, 2008 | 166 | 2008 |
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma S Pfister, S Rea, M Taipale, F Mendrzyk, B Straub, C Ittrich, O Thuerigen, ... International journal of cancer 122 (6), 1207-1213, 2008 | 165 | 2008 |
Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification JJ Quinn, IA Ilik, K Qu, P Georgiev, C Chu, A Akhtar, HY Chang Nature biotechnology 32 (9), 933-940, 2014 | 159 | 2014 |
Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila IA Ilik, JJ Quinn, P Georgiev, F Tavares-Cadete, D Maticzka, S Toscano, ... Molecular cell 51 (2), 156-173, 2013 | 155 | 2013 |
The nonspecific lethal complex is a transcriptional regulator in Drosophila SJ Raja, I Charapitsa, T Conrad, JM Vaquerizas, P Gebhardt, H Holz, ... Molecular cell 38 (6), 827-841, 2010 | 149 | 2010 |
Males absent on the first (MOF): from flies to humans S Rea, G Xouri, A Akhtar Oncogene 26 (37), 5385-5394, 2007 | 141 | 2007 |
Functional integration of the histone acetyltransferase MOF into the dosage compensation complex V Morales, T Straub, MF Neumann, G Mengus, A Akhtar, PB Becker The EMBO journal 23 (11), 2258-2268, 2004 | 139 | 2004 |
Rapid evolutionary turnover underlies conserved lncRNA–genome interactions JJ Quinn, QC Zhang, P Georgiev, IA Ilik, A Akhtar, HY Chang Genes & development 30 (2), 191-207, 2016 | 131 | 2016 |
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing Y Zhou, KM Schmitz, C Mayer, X Yuan, A Akhtar, I Grummt Nature cell biology 11 (8), 1010-1016, 2009 | 116 | 2009 |