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Thomas Luechtefeld
Thomas Luechtefeld
Insilica
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Zitiert von
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Machine learning of toxicological big data enables read-across structure activity relationships (RASAR) outperforming animal test reproducibility
T Luechtefeld, D Marsh, C Rowlands, T Hartung
Toxicological Sciences 165 (1), 198-212, 2018
2722018
T4 report: Toward good read-across practice (GRAP) guidance
N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ...
Altex 33 (2), 149, 2016
1942016
Food for thought… integrated testing strategies for safety assessments
T Hartung, T Luechtefeld, A Maertens, A Kleensang
Altex 30 (1), 3, 2013
1752013
Integrated Testing Strategies (ITS) for safety assessment.
C Rovida, N Alépée, AM Api, DA Basketter, F y Bois, F Caloni, E Corsini, ...
ALTEX-Alternatives to Animal Experimentations 32 (1), 25-40, 2015
1722015
Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008–2014 REACH data
T Luechtefeld, A Maertens, DP Russo, C Rovida, H Zhu, T Hartung
Altex 33 (2), 123, 2016
1082016
t4 workshop report: pathways of toxicity
A Kleensang, A Maertens, M Rosenberg, S Fitzpatrick, J Lamb, ...
Altex 31 (1), 53, 2014
1082014
t4 report: Supporting read-across using biological data
H Zhu, M Bouhifd, N Kleinstreuer, ED Kroese, Z Liu, T Luechtefeld, ...
Altex 33 (2), 167, 2016
1002016
CATMoS: collaborative acute toxicity modeling suite
K Mansouri, AL Karmaus, J Fitzpatrick, G Patlewicz, P Pradeep, D Alberga, ...
Environmental health perspectives 129 (4), 047013, 2021
882021
Big-data and machine learning to revamp computational toxicology and its use in risk assessment
T Luechtefeld, C Rowlands, T Hartung
Toxicology research 7 (5), 732-744, 2018
742018
Global analysis of publicly available safety data for 9,801 substances registered under REACH from 2008–2014
T Luechtefeld, A Maertens, DP Russo, C Rovida, H Zhu, T Hartung
Altex 33 (2), 95, 2016
702016
Analysis of publically available skin sensitization data from REACH registrations 2008–2014
T Luechtefeld, A Maertens, DP Russo, C Rovida, H Zhu, T Hartung
Altex 33 (2), 135, 2016
642016
Neospora caninum recruits host cell structures to its parasitophorous vacuole and salvages lipids from organelles
SJ Nolan, JD Romano, T Luechtefeld, I Coppens
Eukaryotic cell 14 (5), 454-473, 2015
572015
Sysrev: a FAIR platform for data curation and systematic evidence review
T Bozada Jr, J Borden, J Workman, M Del Cid, J Malinowski, ...
Frontiers in Artificial Intelligence 4, 685298, 2021
502021
Computational approaches to chemical hazard assessment
T Luechtefeld, T Hartung
Altex 34 (4), 459, 2017
502017
Analysis of public oral toxicity data from REACH registrations 2008–2014
T Luechtefeld, A Maertens, DP Russo, C Rovida, H Zhu, T Hartung
Altex 33 (2), 111, 2016
492016
Probabilistic risk assessment–the keystone for the future of toxicology
A Maertens, E Golden, TH Luechtefeld, S Hoffmann, K Tsaioun, T Hartung
Altex 39 (1), 3, 2022
432022
Safer chemicals using less animals: kick-off of the European ONTOX project
M Vinken, E Benfenati, F Busquet, J Castell, DA Clevert, TM de Kok, ...
Toxicology 458, 152846, 2021
432021
A perspective and a new integrated computational strategy for skin sensitization assessment
VM Alves, SJ Capuzzi, RC Braga, JVB Borba, AC Silva, T Luechtefeld, ...
ACS sustainable chemistry & engineering 6 (3), 2845-2859, 2018
372018
Probabilistic hazard assessment for skin sensitization potency by dose–response modeling using feature elimination instead of quantitative structure–activity relationships
T Luechtefeld, A Maertens, JM McKim, T Hartung, A Kleensang, ...
Journal of Applied Toxicology 35 (11), 1361-1371, 2015
352015
MPTP’s pathway of toxicity indicates central role of transcription factor SP1
A Maertens, T Luechtefeld, A Kleensang, T Hartung
Archives of toxicology 89, 743-755, 2015
352015
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