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Theodoros Giavridis
Theodoros Giavridis
Mnemo Therapeutics, Inc.
Bestätigte E-Mail-Adresse bei mnemo-tx.com
Titel
Zitiert von
Zitiert von
Jahr
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
J Eyquem, J Mansilla-Soto, T Giavridis, SJC van der Stegen, M Hamieh, ...
Nature 543 (7643), 113-117, 2017
17092017
CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
T Giavridis, SJC van der Stegen, J Eyquem, M Hamieh, A Piersigilli, ...
Nature Medicine 24 (6), 731–738, 2018
10812018
Senolytic CAR T cells reverse senescence-associated pathologies
C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Curbelo, ...
Nature 583 (7814), 127-132, 2020
6022020
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
M Hamieh, A Dobrin, A Cabriolu, SJC van der Stegen, T Giavridis, ...
Nature 568 (7750), 112-116, 2019
4892019
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy
EC Morris, SS Neelapu, T Giavridis, M Sadelain
Nature Reviews Immunology 22 (2), 85-96, 2022
4232022
The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells
K Mestermann, T Giavridis, J Weber, J Rydzek, S Frenz, T Nerreter, ...
Science translational medicine 11 (499), eaau5907, 2019
3882019
HLA-independent T cell receptors for targeting tumors with low antigen density
J Mansilla-Soto, J Eyquem, S Haubner, M Hamieh, J Feucht, N Paillon, ...
Nature Medicine 28 (2), 345-352, 2022
912022
Disruption of SUV39H1-mediated H3K9 methylation sustains CAR T cell function
N Jain, Z Zhao, RP Koche, C Antelope, Y Gozlan, A Montalbano, D Brocks, ...
Cancer Discovery, 2023
52023
Novel therapeutic interventions to alleviate CAR T cell-induced cytokine release syndrome
T Giavridis, SJ Stegen, J Eyquem, M Hamieh, M Sadelain
Cancer Research 78 (13_Supplement), 2567-2567, 2018
12018
132 HLA-independent T cell receptors effectively target low abundance antigens
J Mansilla-Soto, J Eyquem, S Haubner, M Hamieh, J Feucht, N Paillon, ...
Journal for Immunotherapy of Cancer 9 (Suppl 2), A142-A142, 2021
2021
Methods and compositions for alleviating cytokine release syndrome
M Sadelain, T Giavridis
US Patent App. 15/931,027, 2020
2020
Restraining Macrophages Alleviates CAR T Cell-Induced Cytokine Release Syndrome and Informs Novel Therapeutic Interventions
T Giavridis, SJC van der Stegen, J Eyquem, M Hamieh, M Sadelain
MOLECULAR THERAPY 26 (5), 173-173, 2018
2018
CRISPR/Cas9-Mediated Targeting of a CAR into the TRAC Locus Enhances CAR T Cell-Mediated Tumor Rejection
J Mansilla-Soto, J Eyquem, T Giavridis, SJC van der Stegen, M Hamieh, ...
MOLECULAR THERAPY 25 (5), 229-229, 2017
2017
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