| Knocking down disease: a progress report on siRNA therapeutics A Wittrup, J Lieberman Nature Reviews Genetics 16 (9), 543-552, 2015 | 927 | 2015 |
| Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1 KJ Svensson, HC Christianson, A Wittrup, E Bourseau-Guilmain, ... Journal of Biological Chemistry 288 (24), 17713-17724, 2013 | 736 | 2013 |
| Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown A Wittrup, A Ai, X Liu, P Hamar, R Trifonova, K Charisse, M Manoharan, ... Nature biotechnology 33 (8), 870-876, 2015 | 516 | 2015 |
| The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis S Sandgren, A Wittrup, F Cheng, M Jönsson, E Eklund, S Busch, ... Journal of Biological Chemistry 279 (17), 17951-17956, 2004 | 292 | 2004 |
| Nuclear delivery of macromolecules: barriers and carriers M Belting, S Sandgren, A Wittrup Advanced drug delivery reviews 57 (4), 505-527, 2005 | 265 | 2005 |
| Nanotubes, exosomes, and nucleic acid–binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease M Belting, A Wittrup The Journal of cell biology 183 (7), 1187, 2008 | 219 | 2008 |
| Imaging small molecule-induced endosomal escape of siRNA H Du Rietz, H Hedlund, S Wilhelmson, P Nordenfelt, A Wittrup Nature communications 11 (1), 1809, 2020 | 126 | 2020 |
| N-terminal peptides from unprocessed prion proteins enter cells by macropinocytosis M Magzoub, S Sandgren, P Lundberg, K Oglęcka, J Lilja, A Wittrup, ... Biochemical and biophysical research communications 348 (2), 379-385, 2006 | 114 | 2006 |
| Gene knockdown by EpCAM aptamer–siRNA chimeras suppresses epithelial breast cancers and their tumor-initiating cells A Gilboa-Geffen, P Hamar, MTN Le, LA Wheeler, R Trifonova, F Petrocca, ... Molecular cancer therapeutics 14 (10), 2279-2291, 2015 | 85 | 2015 |
| Gene knockdown by EpCAM aptamer–siRNA chimeras suppresses epithelial breast cancers and their tumor-initiating cells A Gilboa-Geffen, P Hamar, MTN Le, LA Wheeler, R Trifonova, F Petrocca, ... Molecular cancer therapeutics 14 (10), 2279-2291, 2015 | 85 | 2015 |
| Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery A Wittrup, SH Zhang, KJ Svensson, P Kucharzewska, MC Johansson, ... Proceedings of the National Academy of Sciences 107 (30), 13342-13347, 2010 | 81 | 2010 |
| ScFv antibody-induced translocation of cell-surface heparan sulfate proteoglycan to endocytic vesicles A Wittrup, SH Zhang, GB Ten Dam, TH van Kuppevelt, P Bengtson, ... Journal of Biological Chemistry 284 (47), 32959-32967, 2009 | 71 | 2009 |
| Identification of proteins released by mammalian cells that mediate DNA internalization through proteoglycan-dependent macropinocytosis A Wittrup, S Sandgren, J Lilja, C Bratt, N Gustavsson, M Mörgelin, ... Journal of biological chemistry 282 (38), 27897-27904, 2007 | 50 | 2007 |
| Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation JE Welch, P Bengtson, K Svensson, A Wittrup, GJ Jenniskens, ... International journal of oncology 32 (4), 749-756, 2008 | 40 | 2008 |
| Macromolecular drug delivery: basic principles and therapeutic applications M Belting, A Wittrup Molecular biotechnology 43, 89-94, 2009 | 32 | 2009 |
| Cancer Cells Can Exhibit a Sparing FLASH Effect at Low Doses Under Normoxic In Vitro-Conditions G Adrian, E Konradsson, S Beyer, A Wittrup, KT Butterworth, SJ McMahon, ... Frontiers in oncology 11, 686142, 2021 | 31 | 2021 |
| Developments in macromolecular drug delivery M Belting, A Wittrup Macromolecular Drug Delivery: Methods and Protocols, 1-10, 2009 | 30 | 2009 |
| Auto-segmentations by convolutional neural network in cervical and anorectal cancer with clinical structure sets as the ground truth H Sartor, D Minarik, O Enqvist, J Ulén, A Wittrup, M Bjurberg, E Trägårdh Clinical and Translational Radiation Oncology 25, 37-45, 2020 | 19 | 2020 |
| Studies of proteoglycan involvement in CPP-mediated delivery A Wittrup, SH Zhang, M Belting Cell-Penetrating Peptides: Methods and Protocols, 99-115, 2011 | 15 | 2011 |
| Characterizing peptide-mediated DNA internalization in human cancer cells A Wittrup, M Belting Macromolecular Drug Delivery: Methods and Protocols, 101-112, 2009 | 10 | 2009 |
Mattias BeltingProfessor/Senior Consultant of Oncology, Lund University, Lund, Sweden.Verified email at med.lu.se
