Severe COVID-19 is marked by a dysregulated myeloid cell compartment J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ... Cell 182 (6), 1419-1440. e23, 2020 | 1411 | 2020 |
A physical and functional map of the human TNF-α/NF-κB signal transduction pathway T Bouwmeester, A Bauch, H Ruffner, PO Angrand, G Bergamini, ... Nature cell biology 6 (2), 97-105, 2004 | 1346 | 2004 |
Deep learning: new computational modelling techniques for genomics G Eraslan, Ž Avsec, J Gagneur, FJ Theis Nature Reviews Genetics 20 (7), 389-403, 2019 | 1122 | 2019 |
Bidirectional promoters generate pervasive transcription in yeast Z Xu, W Wei, J Gagneur, F Perocchi, S Clauder-Münster, J Camblong, ... Nature 457 (7232), 1033-1037, 2009 | 1091 | 2009 |
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues D Wang, B Eraslan, T Wieland, B Hallström, T Hopf, DP Zolg, J Zecha, ... Molecular systems biology 15 (2), e8503, 2019 | 688 | 2019 |
The genomic and transcriptomic landscape of a HeLa cell line JJM Landry, PT Pyl, T Rausch, T Zichner, MM Tekkedil, AM Stütz, A Jauch, ... G3: Genes, Genomes, Genetics 3 (8), 1213-1224, 2013 | 645 | 2013 |
Genetic diagnosis of Mendelian disorders via RNA sequencing LS Kremer, DM Bader, C Mertes, R Kopajtich, G Pichler, A Iuso, TB Haack, ... Nature communications 8 (1), 15824, 2017 | 571 | 2017 |
TT-seq maps the human transient transcriptome B Schwalb, M Michel, B Zacher, K Frühauf, C Demel, A Tresch, J Gagneur, ... Science 352 (6290), 1225-1228, 2016 | 525 | 2016 |
Base-resolution models of transcription-factor binding reveal soft motif syntax Ž Avsec, M Weilert, A Shrikumar, S Krueger, A Alexandari, K Dalal, ... Nature genetics 53 (3), 354-366, 2021 | 491 | 2021 |
Combinatorial binding predicts spatio-temporal cis-regulatory activity RP Zinzen, C Girardot, J Gagneur, M Braun, EEM Furlong Nature 462 (7269), 65-70, 2009 | 484 | 2009 |
Computation of elementary modes: a unifying framework and the new binary approach J Gagneur, S Klamt BMC bioinformatics 5, 1-21, 2004 | 355 | 2004 |
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 338 | 2020 |
Transcriptome surveillance by selective termination of noncoding RNA synthesis D Schulz, B Schwalb, A Kiesel, C Baejen, P Torkler, J Gagneur, J Soeding, ... Cell 155 (5), 1075-1087, 2013 | 275 | 2013 |
Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila K Oktaba, L Gutiérrez, J Gagneur, C Girardot, AK Sengupta, EEM Furlong, ... Developmental cell 15 (6), 877-889, 2008 | 242 | 2008 |
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe, ... Immunity 54 (11), 2650-2669. e14, 2021 | 211 | 2021 |
Antisense expression increases gene expression variability and locus interdependency Z Xu, W Wei, J Gagneur, S Clauder‐Münster, M Smolik, W Huber, ... Molecular systems biology 7 (1), 468, 2011 | 210 | 2011 |
GOing Bayesian: model-based gene set analysis of genome-scale data S Bauer, J Gagneur, PN Robinson Nucleic acids research 38 (11), 3523-3532, 2010 | 198 | 2010 |
MMSplice: modular modeling improves the predictions of genetic variant effects on splicing J Cheng, TYD Nguyen, KJ Cygan, MH Çelik, WG Fairbrother, Ž Avsec, ... Genome biology 20, 1-15, 2019 | 189 | 2019 |
Modular decomposition of protein-protein interaction networks J Gagneur, R Krause, T Bouwmeester, G Casari Genome biology 5, 1-12, 2004 | 181 | 2004 |
OUTRIDER: a statistical method for detecting aberrantly expressed genes in RNA sequencing data F Brechtmann, C Mertes, A Matusevičiūtė, VA Yépez, Ž Avsec, M Herzog, ... The American Journal of Human Genetics 103 (6), 907-917, 2018 | 178 | 2018 |