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Julien lescar
Julien lescar
Verified email at ntu.edu.sg
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Cited by
Cited by
Year
Structure of a flavivirus envelope glycoprotein in its low‐pH‐induced membrane fusion conformation
S Bressanelli, K Stiasny, SL Allison, EA Stura, S Duquerroy, J Lescar, ...
The EMBO journal 23 (4), 728-738, 2004
7422004
The fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH
J Lescar, A Roussel, MW Wien, J Navaza, SD Fuller, G Wengler, ...
Cell 105 (1), 137-148, 2001
6492001
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution
TL Yap, T Xu, YL Chen, H Malet, MP Egloff, B Canard, SG Vasudevan, ...
Journal of virology 81 (9), 4753-4765, 2007
4942007
Conventional and unconventional mechanisms for capping viral mRNA
E Decroly, F Ferron, J Lescar, B Canard
Nature Reviews Microbiology 10 (1), 51-65, 2012
4932012
Ten years of dengue drug discovery: progress and prospects
SP Lim, QY Wang, CG Noble, YL Chen, H Dong, B Zou, F Yokokawa, ...
Antiviral research 100 (2), 500-519, 2013
3942013
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex
E Decroly, C Debarnot, F Ferron, M Bouvet, B Coutard, I Imbert, L Gluais, ...
PLoS pathogens 7 (5), e1002059, 2011
3622011
Crystal structure of the NS3 protease-helicase from dengue virus
D Luo, T Xu, C Hunke, G Gruber, SG Vasudevan, J Lescar
Journal of virology 82 (1), 173-183, 2008
3512008
The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development
D Luo, SG Vasudevan, J Lescar
Antiviral research 118, 148-158, 2015
3052015
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein
D Luo, T Xu, RP Watson, D Scherer‐Becker, A Sampath, W Jahnke, ...
The EMBO journal 27 (23), 3209-3219, 2008
2962008
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
H Malet, B Coutard, S Jamal, H Dutartre, N Papageorgiou, M Neuvonen, ...
Journal of virology 83 (13), 6534-6545, 2009
2752009
Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target
J Lescar, D Luo, T Xu, A Sampath, SP Lim, B Canard, SG Vasudevan
Antiviral research 80 (2), 94-101, 2008
2622008
Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 A
T Xu, A Sampath, A Chao, D Wen, M Nanao, P Chene, SG Vasudevan, ...
Journal of virology 79 (16), 10278-10288, 2005
2582005
Structure of the Functional Form of the Mosquito Larvicidal Cry4Aa Toxin from Bacillus thuringiensis at a 2.8-Angstrom Resolution
P Boonserm, M Mo, C Angsuthanasombat, J Lescar
Journal of bacteriology 188 (9), 3391-3401, 2006
2552006
The flavivirus polymerase as a target for drug discovery
H Malet, N Massé, B Selisko, JL Romette, K Alvarez, JC Guillemot, ...
Antiviral research 80 (1), 23-35, 2008
2482008
Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein
JJH Chu, R Rajamanonmani, J Li, R Bhuvanakantham, J Lescar, ML Ng
Journal of General Virology 86 (2), 405-412, 2005
2412005
Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
WW Phoo, Y Li, Z Zhang, MY Lee, YR Loh, YB Tan, EY Ng, J Lescar, ...
Nature communications 7 (1), 13410, 2016
2152016
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication
Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ...
PLoS pathogens 11 (3), e1004682, 2015
2152015
Biochemical and structural analysis of Helix pomatia agglutinin: A hexameric lectin with a novel fold
JF Sanchez, J Lescar, V Chazalet, A Audfray, J Gagnon, R Alvarez, ...
Journal of Biological Chemistry 281 (29), 20171-20180, 2006
2062006
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
B Morin, B Coutard, M Lelke, F Ferron, R Kerber, S Jamal, A Frangeul, ...
PLoS pathogens 6 (9), e1001038, 2010
1962010
Engineering a catalytically efficient recombinant protein ligase
R Yang, YH Wong, GKT Nguyen, JP Tam, J Lescar, B Wu
Journal of the American Chemical Society 139 (15), 5351-5358, 2017
1862017
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