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derek warren
derek warren
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Verified email at uea.ac.uk
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Year
Nesprin-1 and-2 are involved in the pathogenesis of Emery–Dreifuss muscular dystrophy and are critical for nuclear envelope integrity
Q Zhang, C Bethmann, NF Worth, JD Davies, C Wasner, A Feuer, ...
Human molecular genetics 16 (23), 2816-2833, 2007
5572007
Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging
CD Ragnauth, DT Warren, Y Liu, R McNair, T Tajsic, N Figg, R Shroff, ...
Circulation 121 (20), 2200-2210, 2010
3942010
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
Q Zhang, CD Ragnauth, JN Skepper, NF Worth, DT Warren, RG Roberts, ...
Journal of cell science 118 (4), 673-687, 2005
3232005
Nesprins LINC the nucleus and cytoskeleton
JA Mellad, DT Warren, CM Shanahan
Current opinion in cell biology 23 (1), 47-54, 2011
1782011
Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics
DT Warren, PD Andrews, CW Gourlay, KR Ayscough
Journal of cell science 115 (8), 1703-1715, 2002
1572002
Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function?
DT Warren, Q Zhang, PL Weissberg, CM Shanahan
Expert reviews in molecular medicine 7 (11), 1-15, 2005
1462005
Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis
C Zhou, C Li, B Zhou, H Sun, V Koullourou, I Holt, MJ Puckelwartz, ...
Human molecular genetics 26 (12), 2258-2276, 2017
912017
A 28-kDa splice variant of NADPH oxidase-4 is nuclear-localized and involved in redox signaling in vascular cells
N Anilkumar, GS Jose, I Sawyer, CXC Santos, C Sand, AC Brewer, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (4), e104-e112, 2013
912013
An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast
CW Gourlay, H Dewar, DT Warren, R Costa, N Satish, KR Ayscough
Journal of cell science 116 (12), 2551-2564, 2003
872003
Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle …
DT Warren, T Tajsic, JA Mellad, R Searles, Q Zhang, CM Shanahan
Journal of Biological Chemistry 285 (2), 1311-1320, 2010
652010
Novel Proteins Linking the Actin Cytoskeleton to the Endocytic Machinery in Saccharomyces cerevisiae
H Dewar, DT Warren, FC Gardiner, CG Gourlay, N Satish, MR Richardson, ...
Molecular biology of the cell 13 (10), 3646-3661, 2002
632002
Vascular stem/progenitor cell migration induced by smooth muscle cell-derived chemokine (CC motif) ligand 2 and chemokine (CXC motif) ligand 1 contributes to neointima formation
B Yu, MM Wong, CMF Potter, RML Simpson, E Karamariti, Z Zhang, ...
Stem cells 34 (9), 2368-2380, 2016
552016
Prelamin A impairs 53 BP 1 nuclear entry by mislocalizing NUP 153 and disrupting the Ran gradient
AM Cobb, D Larrieu, DT Warren, Y Liu, S Srivastava, AJO Smith, ...
Aging cell 15 (6), 1039-1050, 2016
502016
Hyaluronan is crucial for stem cell differentiation into smooth muscle lineage
RML Simpson, X Hong, MM Wong, E Karamariti, SI Bhaloo, D Warren, ...
Stem Cells 34 (5), 1225-1238, 2016
362016
Lsb5p interacts with actin regulators Sla1p and Las17p, ubiquitin and Arf3p to couple actin dynamics to membrane trafficking processes
R Costa, DT Warren, KR Ayscough
Biochemical Journal 387 (3), 649-658, 2005
332005
Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing
DT Warren, T Tajsic, LJ Porter, RM Minaisah, A Cobb, A Jacob, D Rajgor, ...
Cell Death & Differentiation 22 (9), 1540-1550, 2015
322015
Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling
AM Cobb, TV Murray, DT Warren, Y Liu, CM Shanahan
Nucleus 7 (5), 498-511, 2016
312016
Adventitial SCA-1+ progenitor cell gene sequencing reveals the mechanisms of cell migration in response to hyperlipidemia
I Kokkinopoulos, MM Wong, CMF Potter, Y Xie, B Yu, DT Warren, ...
Stem Cell Reports 9 (2), 681-696, 2017
282017
Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging
DT Warren, CM Shanahan
Biochemical Society Transactions 39 (6), 1780-1785, 2011
262011
Vascular smooth muscle cell contractile function and mechanotransduction
S Ahmed, DT Warren
Vessel Plus 2, 36, 2018
212018
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