| Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3 C Diehl, O Engstrom, T Delaine, M Håkansson, S Genheden, K Modig, ... Journal of the American Chemical Society 132 (41), 14577-14589, 2010 | 252 | 2010 |
| The carbohydrate-binding site in galectin-3 is preorganized to recognize a sugarlike framework of oxygens: ultra-high-resolution structures and water dynamics K Saraboji, M Håkansson, S Genheden, C Diehl, J Qvist, U Weininger, ... Biochemistry 51 (1), 296-306, 2012 | 179 | 2012 |
| Crystal structures of the Chromobacterium violaceumω‐transaminase reveal major structural rearrangements upon binding of coenzyme PLP MS Humble, KE Cassimjee, M Håkansson, YR Kimbung, B Walse, ... The FEBS journal 279 (5), 779-792, 2012 | 141 | 2012 |
| Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence K Petersson, M Håkansson, H Nilsson, G Forsberg, LA Svensson, A Liljas, ... The EMBO journal, 2001 | 123 | 2001 |
| Monosaccharide derivatives with low‐nanomolar lectin affinity and high selectivity based on combined fluorine–amide, phenyl–arginine, sulfur–π, and halogen bond interactions FR Zetterberg, K Peterson, RE Johnsson, T Brimert, M Håkansson, ... ChemMedChem 13 (2), 133-137, 2018 | 108 | 2018 |
| Structural basis for the negative for the negative allostery between Ca2+ and Mg2+ -binding in the intracellular Ca2+-receptor calbindin D9k F Maria Håkansson, Anders, Malmendal, Sara, Linse, Ivar, Ivarsson, Sture Protein Science 6, 1139, 1997 | 98 | 1997 |
| Systematic tuning of fluoro-galectin-3 interactions provides thiodigalactoside derivatives with single-digit nM affinity and high selectivity K Peterson, R Kumar, O Stenström, P Verma, PR Verma, ... Journal of medicinal chemistry 61 (3), 1164-1175, 2018 | 91 | 2018 |
| A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage MJGW Ladds, IMM Van Leeuwen, CJ Drummond, S Chu, AR Healy, ... Nature communications 9 (1), 1107, 2018 | 88 | 2018 |
| The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules M Håkansson, K Petersson, H Nilsson, G Forsberg, P Björk, P Antonsson, ... Journal of molecular biology 302 (3), 527-537, 2000 | 68 | 2000 |
| Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH A Badarau, H Rouha, S Malafa, DT Logan, M Håkansson, L Stulik, ... Journal of Biological Chemistry 290 (1), 142-156, 2015 | 64 | 2015 |
| Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1 G Svensson, W Awad, M Håkansson, K Mani, DT Logan Journal of biological chemistry 287 (17), 14040-14051, 2012 | 64 | 2012 |
| Structural basis for carbohydrate-binding specificity—A comparative assessment of two engineered carbohydrate-binding modules L von Schantz, M Håkansson, DT Logan, B Walse, J Österlin, ... Glycobiology 22 (7), 948-961, 2012 | 49 | 2012 |
| An extended hudrophobic core induces EF‐hand swapping M Håkansson, A Svensson, J Fast, S Linse Protein Science 10 (5), 927-933, 2001 | 48 | 2001 |
| Amine Transaminase from Exophiala Xenobiotica—Crystal Structure and Engineering of a Fold IV Transaminase that Naturally Converts Biaryl Ketones A Telzerow, J Paris, M Håkansson, J González-Sabín, N Ríos-Lombardía, ... Acs Catalysis 9 (2), 1140-1148, 2018 | 41 | 2018 |
| Protein reconstitution and 3D domain swapping M Hakansson, S Linse Current Protein and Peptide Science 3 (6), 629-642, 2002 | 41 | 2002 |
| Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C B Korkmaz, A Lesner, M Wysocka, A Gieldon, M Håkansson, F Gauthier, ... Biochemical pharmacology 164, 349-367, 2019 | 30 | 2019 |
| MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM JB Casaletto, ML Geddie, AO Abu-Yousif, K Masson, A Fulgham, ... Proceedings of the National Academy of Sciences 116 (15), 7533-7542, 2019 | 28 | 2019 |
| Going to extremes–a metagenomic journey into the dark matter of life A Aevarsson, AK Kaczorowska, BT Adalsteinsson, J Ahlqvist, ... FEMS microbiology letters 368 (12), fnab067, 2021 | 24 | 2021 |
| Designing interactions by control of protein–ligand complex conformation: tuning arginine–arene interaction geometry for enhanced electrostatic protein–ligand interactions AL Noresson, O Aurelius, CT Öberg, O Engström, AP Sundin, ... Chemical Science 9 (4), 1014-1021, 2018 | 24 | 2018 |
| Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand SZ Fisher, L von Schantz, M Håkansson, DT Logan, M Ohlin Biochemistry 54 (42), 6435-6438, 2015 | 20 | 2015 |
