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Sophia Bardehle
Sophia Bardehle
Sr Scientist, MRL Boston
Bestätigte E-Mail-Adresse bei merck.com
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Zitiert von
Zitiert von
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Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation
S Bardehle, M Krüger, F Buggenthin, J Schwausch, J Ninkovic, H Clevers, ...
Nature neuroscience 16 (5), 580-586, 2013
4622013
Fibrinogen activates BMP signaling in oligodendrocyte progenitor cells and inhibits remyelination after vascular damage
MA Petersen, JK Ryu, KJ Chang, A Etxeberria, S Bardehle, AS Mendiola, ...
Neuron 96 (5), 1003-1012. e7, 2017
1702017
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration
JK Ryu, VA Rafalski, A Meyer-Franke, RA Adams, SB Poda, ...
Nature immunology 19 (11), 1212-1223, 2018
1672018
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
AS Mendiola, JK Ryu, S Bardehle, A Meyer-Franke, KKH Ang, C Wilson, ...
Nature immunology 21 (5), 513-524, 2020
1442020
Microglial Gi-dependent dynamics regulate brain network hyperexcitability
M Merlini, VA Rafalski, K Ma, KY Kim, EA Bushong, PE Rios Coronado, ...
Nature neuroscience 24 (1), 19-23, 2021
992021
Genetic deletion of cdc42 reveals a crucial role for astrocyte recruitment to the injury site in vitro and in vivo
S Robel, S Bardehle, A Lepier, C Brakebusch, M Götz
Journal of Neuroscience 31 (35), 12471-12482, 2011
992011
Breaking boundaries—coagulation and fibrinolysis at the neurovascular interface
S Bardehle, VA Rafalski, K Akassoglou
Frontiers in cellular neuroscience 9, 354, 2015
802015
Superficial nephrons in BALB/c and C57BL/6 mice facilitate in vivo multiphoton microscopy of the kidney
IM Schießl, S Bardehle, H Castrop
PLoS One 8 (1), e52499, 2013
452013
C57BL6 mouse substrains demonstrate differences in susceptibility to the demyelinating effects of Cuprizone toxin
E O’Loughlin, B Jacob, G Zeballos, P Manfre, A McCullough, NT Gatto, ...
bioRxiv, 2020.12. 17.423334, 2020
32020
3D profiling of amyloid plaque-associated microglia and neuronal damage on confocal fluorescence images to aid drug discovery in Alzheimer's disease
I Icke, A Zhang, S Singh, B Dogdas, C Mirescu, ME Kennedy, S Bardehle
Medical Imaging 2019: Digital Pathology 10956, 137-145, 2019
22019
High-Resolution Ex Vivo Tissue Clearing, Lightsheet Imaging, and Data Analysis to Support Macromolecular Drug and Biomarker Distribution in Whole Organs and Tumors
N Kumar, P Hrobař, M Vagenknecht, J Soukup, P Bloomingdale, ...
Microscopy and Microanalysis 28 (S1), 1436-1437, 2022
12022
Finding the'ubiquitous' threads in infection and autoimmune neuroinflammation
S Bardehle, V Rafalski, K Akassoglou
Nature immunology 18 (1), 7-8, 2017
12017
Microglial roles in Alzheimer's disease: An agent‐based model to elucidate microglial spatiotemporal response to beta‐amyloid
C Weathered, S Bardehle, C Yoon, N Kumar, CEG Leyns, ME Kennedy, ...
CPT: Pharmacometrics & Systems Pharmacology 13 (3), 449-463, 2024
2024
Neuroimmune cortical organoids overexpressing C4A exhibit multiple schizophrenia endophenotypes
MM Stanton, S Modan, PM Taylor, HN Hariani, J Sorokin, BG Rash, ...
bioRxiv, 2023.01. 20.524955, 2023
2023
A Light sheet fluorescence microscopy and machine learning-based approach to investigate drug and biomarker distribution in whole organs and tumors.
N Kumar, P Hrobar, M Vagenknecht, J Soukup, N Patterson, ...
bioRxiv, 2023.09. 16.558068, 2023
2023
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation (Apri, 10.1038/s41590-020-0654-0, 2020)
AS Mendiola, JK Ryu, S Bardehle, A Meyer-Franke, KKH Ang, C Wilson, ...
NATURE IMMUNOLOGY 21 (9), 1135-1135, 2020
2020
Heterogeneity in astrocyte responses after acute injury in vitro and in vivo
S Bardehle
lmu, 2013
2013
PROLIFERATION OF REACTIVE ASTROCYTES IS ENRICHED IN JUXTAVASCULAR POSITIONS
J Frik, S Bardehle, M Krueger, I Bechmann, L Dimou, N Plesnila, M Goetz
GLIA 61, S52-S52, 2013
2013
IN VIVO LIVE IMAGING OF ASTROGLIAL RECRUITMENT UPON ACUTE CORTICAL INJURY
S Bardehle, M Meyer-Luehmann, L Dimou, M Goetz
GLIA 59, S85-S85, 2011
2011
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