| Evolutionary rate in the protein interaction network HB Fraser, AE Hirsh, LM Steinmetz, C Scharfe, MW Feldman Science 296 (5568), 750-752, 2002 | 1019 | 2002 |
| Factors underlying variable DNA methylation in a human community cohort LL Lam, E Emberly, HB Fraser, SM Neumann, E Chen, GE Miller, ... Proceedings of the National Academy of Sciences 109 (supplement_2), 17253-17260, 2012 | 537 | 2012 |
| Protein dispensability and rate of evolution AE Hirsh, HB Fraser Nature 411 (6841), 1046-1049, 2001 | 493 | 2001 |
| Noise minimization in eukaryotic gene expression HB Fraser, AE Hirsh, G Giaever, J Kumm, MB Eisen PLoS biology 2 (6), e137, 2004 | 486 | 2004 |
| N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility SB Snapper, F Takeshima, I Antón, CH Liu, SM Thomas, D Nguyen, ... Nature cell biology 3 (10), 897-904, 2001 | 404 | 2001 |
| Detecting putative orthologs DP Wall, HB Fraser, AE Hirsh Bioinformatics 19 (13), 1710-1711, 2003 | 344 | 2003 |
| Functional genomic analysis of the rates of protein evolution DP Wall, AE Hirsh, HB Fraser, J Kumm, G Giaever, MB Eisen, ... Proceedings of the National Academy of Sciences 102 (15), 5483-5488, 2005 | 323 | 2005 |
| Population-specificity of human DNA methylation HB Fraser, LL Lam, SM Neumann, MS Kobor Genome biology 13, 1-12, 2012 | 320 | 2012 |
| Conservation and Evolution of Cis-Regulatory Systems in Ascomycete Fungi AP Gasch, AM Moses, DY Chiang, HB Fraser, M Berardini, MB Eisen PLoS biology 2 (12), e398, 2004 | 285 | 2004 |
| Coevolution of gene expression among interacting proteins HB Fraser, AE Hirsh, DP Wall, MB Eisen Proceedings of the National Academy of Sciences 101 (24), 9033-9038, 2004 | 274 | 2004 |
| Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing M Yassour, T Kaplan, HB Fraser, JZ Levin, J Pfiffner, X Adiconis, ... Proceedings of the National Academy of Sciences 106 (9), 3264-3269, 2009 | 269 | 2009 |
| Gene expression drives local adaptation in humans HB Fraser Genome research 23 (7), 1089-1096, 2013 | 262 | 2013 |
| Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse T Babak, B DeVeale, EK Tsang, Y Zhou, X Li, KS Smith, KR Kukurba, ... Nature genetics 47 (5), 544-549, 2015 | 228 | 2015 |
| Modularity and evolutionary constraint on proteins HB Fraser Nature genetics 37 (4), 351-352, 2005 | 225 | 2005 |
| A simple dependence between protein evolution rate and the number of protein-protein interactions HB Fraser, DP Wall, AE Hirsh BMC evolutionary biology 3, 1-6, 2003 | 217 | 2003 |
| Aging and gene expression in the primate brain HB Fraser, P Khaitovich, JB Plotkin, S Pääbo, MB Eisen PLoS biology 3 (9), e274, 2005 | 208 | 2005 |
| Functional genetic variants revealed by massively parallel precise genome editing E Sharon, SAA Chen, NM Khosla, JD Smith, JK Pritchard, HB Fraser Cell 175 (2), 544-557. e16, 2018 | 183 | 2018 |
| Evidence for widespread adaptive evolution of gene expression in budding yeast HB Fraser, AM Moses, EE Schadt Proceedings of the National Academy of Sciences 107 (7), 2977-2982, 2010 | 173 | 2010 |
| Accounting for biases in riboprofiling data indicates a major role for proline in stalling translation CG Artieri, HB Fraser Genome research 24 (12), 2011-2021, 2014 | 164 | 2014 |
| Genetic variation in MHC proteins is associated with T cell receptor expression biases E Sharon, LV Sibener, A Battle, HB Fraser, KC Garcia, JK Pritchard Nature genetics 48 (9), 995-1002, 2016 | 149 | 2016 |
