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Shivendra Vikram Singh
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AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis
Chaube B, Malvi P, Singh SV, Mohammad N, Viollet B, Bhat MK
Cell Death and Discovery 10, 2015
141*2015
Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma
N Mohammad, P Malvi, AS Meena, SV Singh, B Chaube, ...
Molecular cancer 13, 1-13, 2014
1212014
Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex
N Mohammad, S Vikram Singh, P Malvi, B Chaube, D Athavale, ...
Scientific reports 5 (1), 11853, 2015
922015
Inherent and acquired resistance to paclitaxel in hepatocellular carcinoma: molecular events involved
AS Meena, A Sharma, R Kumari, N Mohammad, SV Singh, MK Bhat
PLoS One 8 (4), e61524, 2013
922013
Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.
Balkrishna Chaube, Parmanand Malvi, Singh S Vikram, Naoshad Mohammad, Meena ...
Oncotarget 6 (35), 37281-37299, 2015
752015
Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: role of adipokines
P Malvi, B Chaube, V Pandey, MV Vijayakumar, PR Boreddy, ...
Molecular Oncology 9 (3), 689-703, 2015
702015
Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance
PM , Balkrishna Chaube , Shivendra Vikram Singh , Naoshad Mohammad , Vimal ...
Cancer & Metabolism 4 (21), 10.1186/s40170-016-0162-8, 2016
52*2016
Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state
P Malvi, B Chaube, SV Singh, N Mohammad, MV Vijayakumar, S Singh, ...
Cancer & metabolism 6, 1-14, 2018
512018
Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment
SV Singh, AK Ajay, N Mohammad, P Malvi, B Chaube, AS Meena, MK Bhat
Cell death & disease 6 (10), e1934, 2015
362015
Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models
S Singh, W Quarni, M Goralski, S Wan, H Jin, LA Van de Velde, J Fang, ...
Science advances 7 (47), eabj5405, 2021
342021
KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
A D’Oto, J Fang, H Jin, B Xu, S Singh, A Mullasseril, V Jones, A Abu-Zaid, ...
Nature Communications 12 (1), 7204, 2021
222021
Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter
SV Singh, B Chaube, SS Mayengbam, A Singh, P Malvi, N Mohammad, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (3), 166011, 2021
212021
Targeting KDM4 for treating PAX3-FOXO1–driven alveolar rhabdomyosarcoma
S Singh, A Abu-Zaid, H Jin, J Fang, Q Wu, T Wang, H Feng, W Quarni, ...
Science translational medicine 14 (653), eabq2096, 2022
172022
Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma
J Fang, S Singh, C Cheng, S Natarajan, H Sheppard, A Abu-Zaid, ...
Nature Communications 14 (1), 4003, 2023
82023
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma
S Singh, A Abu-Zaid, W Lin, J Low, A Abdolvahabi, H Jin, Q Wu, B Cooke, ...
Iscience, 2020
82020
The Oligostilbene Gnetin H Is a Novel Glycolysis Inhibitor That Regulates Thioredoxin Interacting Protein Expression and Synergizes with OXPHOS Inhibitor in Cancer Cells
S Singh, F De Carlo, MA Ibrahim, P Penfornis, AJ Mouton, SK Tripathi, ...
International Journal of Molecular Sciences 24 (9), 7741, 2023
42023
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics
HM Lee, WC Wright, M Pan, J Low, D Currier, J Fang, S Singh, S Nance, ...
Nature Communications 14 (1), 7332, 2023
12023
Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
JY Ahmed Abu-Zaid, Shivendra Singh, Hongjian Jin, Jie Fang, Qiong Wu
Cell reports Medicine 5 (3), 101468,, 2024
2024
RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity
S Singh, J Fang, H Jin, LA Van de Velde, Q Wu, A Cortes, C Morton, ...
bioRxiv, 2024.03. 21.586157, 2024
2024
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor
C Jablonowski, W Quarni, S Singh, H Tan, DH Bostanthirige, H Jin, ...
eLife, 12:RP90993, 2023
2023
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Articles 1–20