| The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins LS Harrington, GM Findlay, A Gray, T Tolkacheva, S Wigfield, H Rebholz, ... The Journal of cell biology 166 (2), 213-223, 2004 | 1381 | 2004 |
| Restraining PI3K: mTOR signalling goes back to the membrane LS Harrington, GM Findlay, RF Lamb Trends in biochemical sciences 30 (1), 35-42, 2005 | 461 | 2005 |
| The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho RF Lamb, C Roy, TJ Diefenbach, HV Vinters, MW Johnson, DG Jay, ... Nature cell biology 2 (5), 281-287, 2000 | 432 | 2000 |
| T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ... Immunity 39 (6), 1043-1056, 2013 | 375 | 2013 |
| A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling GM Findlay, L Yan, J Procter, V Mieulet, RF Lamb Biochemical Journal 403 (1), 13-20, 2007 | 322 | 2007 |
| Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial W Greenhalf, P Ghaneh, JP Neoptolemos, DH Palmer, TF Cox, RF Lamb, ... Journal of the National Cancer Institute 106 (1), djt347, 2014 | 295 | 2014 |
| Tuberous sclerosis complex tumor suppressor–mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent A Jaeschke, J Hartkamp, M Saitoh, W Roworth, T Nobukuni, A Hodges, ... The Journal of cell biology 159 (2), 217-224, 2002 | 267 | 2002 |
| Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts RF Lamb, BW Ozanne, C Roy, L McGarry, C Stipp, P Mangeat, DG Jay Current Biology 7 (9), 682-688, 1997 | 241 | 1997 |
| AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44 RF Lamb, RF Hennigan, K Turnbull, KD Katsanakis, ED MacKenzie, ... Molecular and cellular biology 17 (2), 963-976, 1997 | 206 | 1997 |
| Oncogene-selective sensitivity to synchronous cell death following modulation of the amino acid nutrient cystine I Poursaitidis, X Wang, T Crighton, C Labuschagne, D Mason, SL Cramer, ... Cell reports 18 (11), 2547-2556, 2017 | 193 | 2017 |
| The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells A Malliri, M Symons, RF Hennigan, AFL Hurlstone, RF Lamb, T Wheeler, ... The Journal of cell biology 143 (4), 1087-1099, 1998 | 183 | 1998 |
| PP2AT61ɛ is an inhibitor of MAP4K3 in nutrient signaling to mTOR L Yan, V Mieulet, D Burgess, GM Findlay, K Sully, J Procter, J Goris, ... Molecular cell 37 (5), 633-642, 2010 | 142 | 2010 |
| Practical histological microdissection for PCR analysis JJ GOING, RF LAMB The Journal of Pathology 179 (1), 121-124, 1996 | 133 | 1996 |
| Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells Y Wang, G Huang, H Zeng, K Yang, RF Lamb, H Chi Proceedings of the National Academy of Sciences 110 (50), E4894-E4903, 2013 | 100 | 2013 |
| Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase L Yan, GM Findlay, R Jones, J Procter, Y Cao, RF Lamb Journal of biological chemistry 281 (29), 19793-19797, 2006 | 78 | 2006 |
| The impact of diabetes mellitus on survival following resection and adjuvant chemotherapy for pancreatic cancer J Kleeff, E Costello, R Jackson, C Halloran, W Greenhalf, P Ghaneh, ... British journal of cancer 115 (7), 887-894, 2016 | 60 | 2016 |
| mTORC2 is the hydrophobic motif kinase for SGK1 L Yan, V Mieulet, RF Lamb Biochemical Journal 416 (3), e19-e21, 2008 | 56 | 2008 |
| Functional expression and molecular characterization of the thyrotrophin-releasing hormone receptor from the rat anterior pituitary gland RE Sellar, PL Taylor, RF Lamb, J Zabavnik, L Anderson, KA Eidne Journal of molecular endocrinology 10 (2), 199-206, 1993 | 55 | 1993 |
| TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation? GM Findlay, LS Harrington, RF Lamb Current opinion in genetics & development 15 (1), 69-76, 2005 | 54 | 2005 |
| Tuberous sclerosis complex: linking cancer to metabolism V Mieulet, RF Lamb Trends in molecular medicine 16 (7), 329-335, 2010 | 53 | 2010 |
Greg FindlayPrincipal Investigator, MRC-PPU, University of DundeeBestätigte E-Mail-Adresse bei dundee.ac.uk
