| Global profiling of lysine reactivity and ligandability in the human proteome SM Hacker, KM Backus, MR Lazear, S Forli, BE Correia, BF Cravatt Nature chemistry 9 (12), 1181-1190, 2017 | 373 | 2017 |
| A proteome-wide atlas of lysine-reactive chemistry ME Abbasov, ME Kavanagh, TA Ichu, MR Lazear, Y Tao, VM Crowley, ... Nature Chemistry 13 (11), 1081-1092, 2021 | 120 | 2021 |
| Isotopically Labeled Desthiobiotin Azide (isoDTB) Tags Enable Global Profiling of the Bacterial Cysteinome PRA Zanon, L Lewald, SM Hacker Angewandte Chemie 132 (7), 2851-2858, 2020 | 92 | 2020 |
| Light-Activatable, 2, 5-Disubstituted Tetrazoles for the Proteome-wide Profiling of Aspartates and Glutamates in Living Bacteria K Bach, BLH Beerkens, PRA Zanon, SM Hacker ACS Central Science 6 (4), 546-554, 2020 | 90 | 2020 |
| Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms P Le, E Kunold, R Macsics, K Rox, MC Jennings, I Ugur, M Reinecke, ... Nature Chemistry 12 (2), 145-158, 2020 | 84 | 2020 |
| Synthesis and fluorescence characteristics of ATP-based FRET probes N Hardt, SM Hacker, A Marx Organic & biomolecular chemistry 11 (48), 8298-8305, 2013 | 56 | 2013 |
| Profiling the proteome-wide selectivity of diverse electrophiles PRA Zanon, F Yu, P Musacchio, L Lewald, M Zollo, K Krauskopf, ... | 54 | 2021 |
| Synthesis and stability of phosphate modified ATP analogues SM Hacker, M Mex, A Marx The Journal of organic chemistry 77 (22), 10450-10454, 2012 | 51 | 2012 |
| Fluorogenic ATP analogues for online monitoring of ATP consumption: observing ubiquitin activation in real time SM Hacker, D Pagliarini, T Tischer, N Hardt, D Schneider, M Mex, ... Angewandte Chemie International Edition 52 (45), 11916-11919, 2013 | 44 | 2013 |
| Fingerprinting differential active site constraints of ATPases SM Hacker, N Hardt, A Buntru, D Pagliarini, M Möckel, TU Mayer, ... Chemical Science 4 (4), 1588-1596, 2013 | 32 | 2013 |
| Selective monitoring of the enzymatic activity of the tumor suppressor Fhit SM Hacker, F Mortensen, M Scheffner, A Marx Angewandte Chemie International Edition 53 (38), 10247-10250, 2014 | 29 | 2014 |
| Phosphate-modified nucleotides for monitoring enzyme activity S Ermert, A Marx, SM Hacker Phosphate Labeling and Sensing in Chemical Biology, 153-177, 2017 | 22 | 2017 |
| Neocarzilin a is a potent inhibitor of Cancer cell motility targeting VAT-1 controlled pathways CML Gleissner, CL Pyka, W Heydenreuter, TF Gronauer, C Atzberger, ... ACS central science 5 (7), 1170-1178, 2019 | 20 | 2019 |
| Direct monitoring of nucleotide turnover in human cell extracts and cells by fluorogenic ATP analogs SM Hacker, A Buntz, A Zumbusch, A Marx ACS chemical biology 10 (11), 2544-2552, 2015 | 19 | 2015 |
| Broad Spectrum Antibiotic Xanthocillin X Effectively Kills Acinetobacter baumannii via Dysregulation of Heme Biosynthesis I Hübner, JA Shapiro, J Hoßmann, J Drechsel, SM Hacker, PN Rather, ... ACS central science 7 (3), 488-498, 2021 | 18 | 2021 |
| Monitoring enzymatic ATP hydrolysis by EPR spectroscopy SM Hacker, C Hintze, A Marx, M Drescher Chemical Communications 50 (55), 7262-7264, 2014 | 17 | 2014 |
| Thiamine Pyrophosphate Stimulates Acetone Activation by Desulfococcus biacutus As Monitored by a Fluorogenic ATP Analogue OB Gutiérrez Acosta, N Hardt, SM Hacker, T Strittmatter, B Schink, A Marx ACS chemical biology 9 (6), 1263-1266, 2014 | 16 | 2014 |
| A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling PWA Allihn, MW Hackl, C Ludwig, SM Hacker, SA Sieber Chemical science 12 (13), 4763-4770, 2021 | 14 | 2021 |
| Competitive profiling of ligandable cysteines in Staphylococcus aureus with an organogold compound C Schmidt, M Zollo, R Bonsignore, A Casini, SM Hacker Chemical Communications 58 (36), 5526-5529, 2022 | 13 | 2022 |
| Degrasyn exhibits antibiotic activity against multi-resistant Staphylococcus aureus by modifying several essential cysteines KM Lee, P Le, SA Sieber, SM Hacker Chemical Communications 56 (19), 2929-2932, 2020 | 10 | 2020 |
