Discovery of potent cytotoxic ortho-aryl chalcones as new scaffold targeting tubulin and mitosis with affinity-based fluorescence C Zhu, Y Zuo, R Wang, B Liang, X Yue, G Wen, N Shang, L Huang, ... Journal of medicinal chemistry 57 (15), 6364-6382, 2014 | 55 | 2014 |
Mitochondria-targeted approach: remarkably enhanced cellular bioactivities of TPP2a as selective inhibitor and probe toward TrxR B Liang, W Shao, C Zhu, G Wen, X Yue, R Wang, J Quan, J Du, X Bu ACS chemical biology 11 (2), 425-434, 2016 | 40 | 2016 |
MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells B Liang, Z Liu, Y Cao, C Zhu, Y Zuo, L Huang, G Wen, N Shang, Y Chen, ... European Journal of Pharmacology 796, 139-148, 2017 | 38 | 2017 |
A furanyl acryl conjugated coumarin as an efficient inhibitor and a highly selective off–on fluorescent probe for covalent labelling of thioredoxin reductase L Huang, Y Chen, B Liang, B Xing, G Wen, S Wang, X Yue, C Zhu, J Du, ... Chemical communications 50 (53), 6987-6990, 2014 | 37 | 2014 |
Synthesis, cytotoxicity of new 4-arylidene curcumin analogues and their multi-functions in inhibition of both NF-κB and Akt signalling Y Zuo, J Huang, B Zhou, S Wang, W Shao, C Zhu, L Lin, G Wen, H Wang, ... European journal of medicinal chemistry 55, 346-357, 2012 | 36 | 2012 |
Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer C Zhu, A Rogers, K Asleh, J Won, D Gao, S Leung, S Li, KR Vij, J Zhu, ... Cell Reports 31 (10), 107745, 2020 | 20 | 2020 |
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling G Feng, C Zhu, Z Li, P Wang, Y Huang, M Liu, P He, L Lou, S Chen, P Liu Acta Pharmacologica Sinica 38 (5), 638-650, 2017 | 18 | 2017 |
Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase X Yue, Y Zuo, H Ke, J Luo, L Lou, W Qin, Y Wang, Z Liu, D Chen, H Sun, ... Biochemical pharmacology 137, 29-50, 2017 | 17 | 2017 |
TYK2 promotes malignant peripheral nerve sheath tumor progression through inhibition of cell death W Qin, A Godec, X Zhang, C Zhu, J Shao, Y Tao, X Bu, AC Hirbe Cancer medicine 8 (11), 5232-5241, 2019 | 16 | 2019 |
Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. mairei ZH Sun, Y Chen, YQ Guo, J Qiu, CG Zhu, J Jin, GH Tang, XZ Bu, S Yin Bioorganic & Medicinal Chemistry Letters 25 (6), 1240-1243, 2015 | 15 | 2015 |
Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1 C Zhu, SJ Kim, A Mooradian, F Wang, Z Li, S Holohan, PL Collins, ... Cell reports 34 (7), 2021 | 14 | 2021 |
Synthesis and evaluation of anticancer activity of BOC26P, an ortho-aryl chalcone sodium phosphate as water-soluble prodrugs in vitro and in vivo C Zhu, R Wang, W Zheng, D Chen, X Yue, Y Cao, W Qin, H Sun, Y Wang, ... Biomedicine & Pharmacotherapy 96, 551-562, 2017 | 10 | 2017 |
Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L C Zhu, M Iwase, Z Li, F Wang, A Quinet, A Vindigni, J Shao Nature communications 13 (1), 6531, 2022 | 3 | 2022 |
Ser71 phosphorylation inhibits actin-binding of profilin-1 and its apoptosis-sensitizing activity F Wang, C Zhu, S Cai, A Boudreau, SJ Kim, M Bissell, J Shao Frontiers in Cell and Developmental Biology 9, 692269, 2021 | 3 | 2021 |
O-phenyl chalcone compounds and preparation method and use thereof X Bu, C Zhu, YUE Xin, Y Zuo, Y Chen, G Wen US Patent 9,663,542, 2017 | 1 | 2017 |
Distinct tubulin dynamics in cancer cells explored using a highly tubulin-specific fluorescent probe C Zhu, Y Zuo, B Liang, H Yue, X Yue, G Wen, R Wang, J Quan, J Du, X Bu Chemical communications 51 (69), 13400-13403, 2015 | 1 | 2015 |
Novel role of the actin-binding factor Profilin-1 in DNA replication C Zhu, SJ Kim, S Holohan, A Rogers, J Shao Cancer Research 78 (13_Supplement), 1372-1372, 2018 | | 2018 |
O-phenyl chalcone compounds and uses thereof X Bu, C Zhu, YUE Xin, Y Zuo, Y Chen, G Wen US Patent 9,988,405, 2018 | | 2018 |