Olga Bruno
Olga Bruno
Professore di Chimica Farmaceutica, Università degli studi di Genova
Bestätigte E-Mail-Adresse bei unige.it
Titel
Zitiert von
Zitiert von
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New 1, 3, 4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities
S Schenone, C Brullo, O Bruno, F Bondavalli, A Ranise, W Filippelli, ...
Bioorganic & medicinal chemistry 14 (6), 1698-1705, 2006
2442006
GEBR‐7b, a novel PDE4D selective inhibitor that improves memory in rodents at non‐emetic doses
O Bruno, E Fedele, J Prickaerts, LA Parker, E Canepa, C Brullo, ...
British journal of pharmacology 164 (8), 2054-2063, 2011
1162011
3-Arylsulphonyl-5-arylamino-1, 3, 4-thiadiazol-2 (3H) ones as anti-inflammatory and analgesic agents
S Schenone, O Bruno, A Ranise, F Bondavalli, W Filippelli, G Falcone, ...
Bioorganic & medicinal chemistry 9 (8), 2149-2153, 2001
1022001
Progress in 5H [1] benzopyrano [4, 3-d] pyrimidin-5-amine series: 2-methoxy derivatives effective as antiplatelet agents with analgesic activity
O Bruno, C Brullo, S Schenone, A Ranise, F Bondavalli, E Barocelli, ...
Il Farmaco 57 (9), 753-758, 2002
982002
New pyrazolo [3, 4-d] pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation
S Schenone, O Bruno, A Ranise, F Bondavalli, C Brullo, P Fossa, L Mosti, ...
Bioorganic & medicinal chemistry letters 14 (10), 2511-2517, 2004
972004
Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation
F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ...
Journal of medicinal chemistry 49 (5), 1549-1561, 2006
952006
Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D
ASR Sierksma, DLA Van Den Hove, F Pfau, M Philippens, O Bruno, ...
Neuropharmacology 77, 120-130, 2014
892014
Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano [4, 3-d] pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano [4, 3-d] pyrimidin-5-ones
O Bruno, C Brullo, S Schenone, F Bondavalli, A Ranise, M Tognolini, ...
Bioorganic & medicinal chemistry 14 (1), 121-130, 2006
882006
Structure-Based Optimization of Pyrazolo[3,4-d]pyrimidines as Abl Inhibitors and Antiproliferative Agents toward Human Leukemia Cell Lines
F Manetti, C Brullo, M Magnani, F Mosci, B Chelli, E Crespan, ...
Journal of medicinal chemistry 51 (5), 1252-1259, 2008
842008
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo [3, 4-d] pyrimidines
S Schenone, C Brullo, O Bruno, F Bondavalli, L Mosti, G Maga, E Crespan, ...
European journal of medicinal chemistry 43 (12), 2665-2676, 2008
802008
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo [3, 4-d] pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line
S Schenone, O Bruno, F Bondavalli, A Ranise, L Mosti, G Menozzi, ...
European journal of medicinal chemistry 39 (11), 939-946, 2004
802004
Identification of a Novel Pyrazolo[3,4-d]pyrimidine Able To Inhibit Cell Proliferation of a Human Osteogenic Sarcoma in Vitro and in a Xenograft Model in Mice
F Manetti, A Santucci, GA Locatelli, G Maga, A Spreafico, T Serchi, ...
Journal of medicinal chemistry 50 (23), 5579-5588, 2007
792007
Antiinflammatory agents: new series of N-substituted amino acids with complex pyrimidine structures endowed with antiphlogistic activity
O Bruno, S Schenone, A Ranise, F Bondavalli, W Filippelli, G Falcone, ...
Il Farmaco 54 (1-2), 95-100, 1999
741999
Synthesis and pharmacological evaluation of 2, 5-cycloamino-5H-[1] benzopyrano [4, 3-d] pyrimidines endowed with in vitro antiplatelet activity
O Bruno, C Brullo, A Ranise, S Schenone, F Bondavalli, E Barocelli, ...
Bioorganic & medicinal chemistry letters 11 (11), 1397-1400, 2001
722001
New polycyclic pyrimidine derivatives with antiplatelet in vitro activity: synthesis and pharmacological screening
O Bruno, S Schenone, A Ranise, F Bondavalli, E Barocelli, V Ballabeni, ...
Bioorganic & medicinal chemistry 9 (3), 629-636, 2001
622001
Synthesis, molecular modeling studies, and pharmacological activity of selective A1 receptor antagonists
F Bondavalli, M Botta, O Bruno, A Ciacci, F Corelli, P Fossa, A Lucacchini, ...
Journal of medicinal chemistry 45 (22), 4875-4887, 2002
612002
Structure-based design, parallel synthesis, structure− activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse …
A Ranise, A Spallarossa, S Cesarini, F Bondavalli, S Schenone, O Bruno, ...
Journal of medicinal chemistry 48 (11), 3858-3873, 2005
602005
Synthesis and 3D QSAR of new pyrazolo [3, 4-b] pyridines: potent and selective inhibitors of A1 adenosine receptors
F Manetti, S Schenone, F Bondavalli, C Brullo, O Bruno, A Ranise, L Mosti, ...
Journal of medicinal chemistry 48 (23), 7172-7185, 2005
582005
Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally …
A Ranise, A Spallarossa, S Schenone, O Bruno, F Bondavalli, L Vargiu, ...
Journal of medicinal chemistry 46 (5), 768-781, 2003
582003
New insights into small‐molecule inhibitors of Bcr‐Abl
S Schenone, O Bruno, M Radi, M Botta
Medicinal research reviews 31 (1), 1-41, 2011
542011
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