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Kelly D. Moynihan
Kelly D. Moynihan
Bestätigte E-Mail-Adresse bei mit.edu
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Structure-based programming of lymph-node targeting in molecular vaccines
H Liu, KD Moynihan, Y Zheng, GL Szeto, AV Li, B Huang, DS Van Egeren, ...
Nature 507 (7493), 519-522, 2014
8772014
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ...
Nature medicine 22 (12), 1402-1410, 2016
5252016
Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
MC Hanson, MP Crespo, W Abraham, KD Moynihan, GL Szeto, SH Chen, ...
The Journal of clinical investigation 125 (6), 2532-2546, 2015
3612015
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2
EF Zhu, SA Gai, CF Opel, BH Kwan, R Surana, MC Mihm, MJ Kauke, ...
Cancer cell 27 (4), 489-501, 2015
2022015
Cell and fluid sampling microneedle patches for monitoring skin-resident immunity
A Mandal, AV Boopathy, LKW Lam, KD Moynihan, ME Welch, NR Bennett, ...
Science translational medicine 10 (467), eaar2227, 2018
1332018
High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry
YSS Yang, PU Atukorale, KD Moynihan, A Bekdemir, K Rakhra, L Tang, ...
Nature communications 8 (1), 14069, 2017
1262017
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy
KL Griffiths, M Ahmed, S Das, R Gopal, W Horne, TD Connell, ...
Nature communications 7 (1), 13894, 2016
1082016
Roles for innate immunity in combination immunotherapies
KD Moynihan, DJ Irvine
Cancer research 77 (19), 5215-5221, 2017
1002017
Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles
YSS Yang, KD Moynihan, A Bekdemir, TM Dichwalkar, MM Noh, ...
Biomaterials science 7 (1), 113-124, 2019
752019
Engineering new approaches to cancer vaccines
NK Mehta, KD Moynihan, DJ Irvine
Cancer immunology research 3 (8), 836-843, 2015
682015
Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability
KD Moynihan, RL Holden, NK Mehta, C Wang, MR Karver, J Dinter, ...
Cancer immunology research 6 (9), 1025-1038, 2018
612018
Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells
K Rakhra, W Abraham, C Wang, KD Moynihan, N Li, N Donahue, ...
Science immunology 6 (57), eabd8003, 2021
542021
Temporally programmed CD8α+ DC activation enhances combination cancer immunotherapy
A Tzeng, MJ Kauke, EF Zhu, KD Moynihan, CF Opel, NJ Yang, N Mehta, ...
Cell reports 17 (10), 2503-2511, 2016
542016
Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines
NK Mehta, RV Pradhan, AP Soleimany, KD Moynihan, AM Rothschilds, ...
Nature biomedical engineering 4 (6), 636-648, 2020
482020
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding
LP Andrews, A Somasundaram, JM Moskovitz, AL Szymczak-Workman, ...
Science immunology 5 (49), eabc2728, 2020
392020
Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide
OK Appelbe, KD Moynihan, A Flor, N Rymut, DJ Irvine, SJ Kron
Journal of Controlled Release 266, 248-255, 2017
262017
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity
CM Backlund, RL Holden, KD Moynihan, D Garafola, C Farquhar, ...
Proceedings of the National Academy of Sciences 119 (32), e2204078119, 2022
242022
Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models
A Rothschilds, A Tzeng, NK Mehta, KD Moynihan, DJ Irvine, KD Wittrup
Oncoimmunology 8 (5), e1558678, 2019
152019
Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy
A Badamchi-Zadeh, KD Moynihan, RA Larocca, M Aid, NM Provine, ...
The Journal of Immunology 201 (9), 2744-2752, 2018
142018
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
KD Wittrup, D Irvine, CF Opel, KD Moynihan
US Patent App. 15/501,246, 2017
142017
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