|SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T …|
JM Chemnitz, RV Parry, KE Nichols, CH June, JL Riley
The Journal of Immunology 173 (2), 945-954, 2004
|Germline mutations in predisposition genes in pediatric cancer|
J Zhang, MF Walsh, G Wu, MN Edmonson, TA Gruber, J Easton, ...
New England Journal of Medicine 373 (24), 2336-2346, 2015
|Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing|
AL Jackson, J Burchard, D Leake, A Reynolds, J Schelter, J Guo, ...
Rna 12 (7), 1197-1205, 2006
|2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American College of …|
A Ravelli, F Minoia, S Davì, AC Horne, F Bovis, A Pistorio, M Aricò, ...
Arthritis & rheumatology 68 (3), 566-576, 2016
|Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy|
DT Teachey, SR Rheingold, SL Maude, G Zugmaier, DM Barrett, AE Seif, ...
Blood, The Journal of the American Society of Hematology 121 (26), 5154-5157, 2013
|Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1|
KE Nichols, JD Crispino, M Poncz, JG White, SH Orkin, JM Maris, ...
Nature genetics 24 (3), 266-270, 2000
|Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome|
KE Nichols, DP Harkin, S Levitz, M Krainer, KA Kolquist, C Genovese, ...
Proceedings of the National Academy of Sciences 95 (23), 13765-13770, 1998
|Recommendations for the management of hemophagocytic lymphohistiocytosis in adults|
P La Rosée, AC Horne, M Hines, T von Bahr Greenwood, R Machowicz, ...
Blood, The Journal of the American Society of Hematology 133 (23), 2465-2477, 2019
|The immunology of macrophage activation syndrome|
CB Crayne, S Albeituni, KE Nichols, RQ Cron
Frontiers in immunology 10, 119, 2019
|Regulation of NKT cell development by SAP, the protein defective in XLP|
KE Nichols, J Hom, SY Gong, A Ganguly, CS Ma, JL Cannons, ...
Nature medicine 11 (3), 340-345, 2005
|Germ-line p53 Mutations Predispose to a Wide Spectrum of Early-onset Cancers|
KE Nichols, D Malkin, JE Garber, JF Fraumeni Jr, FP Li
Cancer Epidemiology Biomarkers & Prevention 10 (2), 83-87, 2001
|Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D|
B Chaigne-Delalande, FY Li, GM O’Connor, MJ Lukacs, P Jiang, L Zheng, ...
Science 341 (6142), 186-191, 2013
|X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease|
C Booth, KC Gilmour, P Veys, AR Gennery, MA Slatter, H Chapel, ...
Blood, The Journal of the American Society of Hematology 117 (1), 53-62, 2011
|Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules|
CS Ma, KE Nichols, SG Tangye
Annu. Rev. Immunol. 25, 337-379, 2007
|Cutting edge: functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome|
SG Tangye, JH Phillips, LL Lanier, KE Nichols
The Journal of Immunology 165 (6), 2932-2936, 2000
|SAP regulates TH2 differentiation and PKC-θ-mediated activation of NF-κB1|
JL Cannons, JY Li, B Hill, LA Mijares, D Dombroski, KE Nichols, ...
Immunity 21 (5), 693-706, 2004
|CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A|
LM Shlapatska, SV Mikhalap, AG Berdova, OM Zelensky, TJ Yun, ...
The Journal of Immunology 166 (9), 5480-5487, 2001
|Molecular and cellular pathogenesis of X‐linked lymphoproliferative disease|
KE Nichols, CS Ma, JL Cannons, PL Schwartzberg, SG Tangye
Immunological reviews 203 (1), 180-199, 2005
|Treatment of E pstein B arr virus‐induced haemophagocytic lymphohistiocytosis with rituximab‐containing chemo‐immunotherapeutic regimens|
DB Chellapandian, R Das, K Zelley, SJ Wiener, H Zhao, DT Teachey, ...
British journal of haematology 162 (3), 376-382, 2013
|Enhanced T cell responses due to diacylglycerol kinase ζ deficiency|
XP Zhong, EA Hainey, BA Olenchock, MS Jordan, JS Maltzman, ...
Nature immunology 4 (9), 882-890, 2003