| Prediction of drug–target interaction networks from the integration of chemical and genomic spaces Y Yamanishi, M Araki, A Gutteridge, W Honda, M Kanehisa Bioinformatics 24 (13), i232-i240, 2008 | 1146 | 2008 |
| Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ... Nature genetics 52 (10), 1122-1131, 2020 | 347 | 2020 |
| Understanding nature's catalytic toolkit A Gutteridge, JM Thornton Trends in biochemical sciences 30 (11), 622-629, 2005 | 287 | 2005 |
| Using a neural network and spatial clustering to predict the location of active sites in enzymes A Gutteridge, GJ Bartlett, JM Thornton Journal of molecular biology 330 (4), 719-734, 2003 | 240 | 2003 |
| Single-cell RNAseq reveals seven classes of colonic sensory neuron JRF Hockley, TS Taylor, G Callejo, AL Wilbrey, A Gutteridge, K Bach, ... Gut 68 (4), 633-644, 2019 | 214 | 2019 |
| SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 203 | 2020 |
| Molecular and functional variation in iPSC-derived sensory neurons J Schwartzentruber, S Foskolou, H Kilpinen, J Rodrigues, K Alasoo, ... Nature genetics 50 (1), 54-61, 2018 | 198 | 2018 |
| Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia L Cao, A McDonnell, A Nitzsche, A Alexandrou, PP Saintot, AJC Loucif, ... Science translational medicine 8 (335), 335ra56-335ra56, 2016 | 187 | 2016 |
| Conformational changes observed in enzyme crystal structures upon substrate binding A Gutteridge, J Thornton Journal of molecular biology 346 (1), 21-28, 2005 | 186 | 2005 |
| Subtype-selective small molecule inhibitors reveal a fundamental role for Nav1. 7 in nociceptor electrogenesis, axonal conduction and presynaptic release AJ Alexandrou, AR Brown, ML Chapman, M Estacion, J Turner, MA Mis, ... PloS one 11 (4), e0152405, 2016 | 171 | 2016 |
| Characterizing human stem cell–derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research GT Young, A Gutteridge, HDE Fox, AL Wilbrey, L Cao, LT Cho, AR Brown, ... Molecular Therapy 22 (8), 1530-1543, 2014 | 146 | 2014 |
| MIMOX: a web tool for phage display based epitope mapping J Huang, A Gutteridge, W Honda, M Kanehisa BMC bioinformatics 7, 1-10, 2006 | 123 | 2006 |
| Conformational change in substrate binding, catalysis and product release: an open and shut case? A Gutteridge, J Thornton FEBS letters 567 (1), 67-73, 2004 | 113 | 2004 |
| Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules B Surmacz, H Fox, A Gutteridge, S Lubitz, P Whiting Stem Cells 30 (9), 1875-1884, 2012 | 93 | 2012 |
| Effective function annotation through catalytic residue conservation RA George, RV Spriggs, GJ Bartlett, A Gutteridge, MW MacArthur, ... Proceedings of the National Academy of Sciences 102 (35), 12299-12304, 2005 | 87 | 2005 |
| Nutrient control of eukaryote cell growth: a systems biology study in yeast A Gutteridge, P Pir, JI Castrillo, PD Charles, KS Lilley, SG Oliver BMC biology 8, 1-20, 2010 | 85 | 2010 |
| Molecular mechanisms mediating retinal reactive gliosis following bone marrow mesenchymal stem cell transplantation A Tassoni, A Gutteridge, AC Barber, A Osborne, KR Martin Stem cells 33 (10), 3006-3016, 2015 | 83 | 2015 |
| Optimizing the leveraging of real-world data to improve the development and use of medicines ML Berger, C Lipset, A Gutteridge, K Axelsen, P Subedi, D Madigan Value in Health 18 (1), 127-130, 2015 | 77 | 2015 |
| The genetic control of growth rate: a systems biology study in yeast P Pir, A Gutteridge, J Wu, B Rash, DB Kell, N Zhang, SG Oliver BMC systems biology 6, 1-17, 2012 | 68 | 2012 |
| Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle A Fisher, RA Seaborne, TM Hughes, A Gutteridge, CE Stewart, ... FASEB journal, 2017 | 57 | 2017 |
paul whitingVerified email at ucl.ac.uk
