David Hackam
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Cited by
Year
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair
CL Leaphart, J Cavallo, SC Gribar, S Cetin, J Li, MF Branca, TD Dubowski, ...
The Journal of Immunology 179 (7), 4808-4820, 2007
4042007
Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier
MD Neal, C Leaphart, R Levy, J Prince, TR Billiar, S Watkins, J Li, S Cetin, ...
The Journal of Immunology 176 (5), 3070-3079, 2006
4042006
Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation
RL Moss, RA Dimmitt, DC Barnhart, KG Sylvester, RL Brown, DM Powell, ...
New England Journal of Medicine 354 (21), 2225-2234, 2006
3932006
The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes
S Gruenheid, F Canonne-Hergaux, S Gauthier, DJ Hackam, S Grinstein, ...
The Journal of experimental medicine 189 (5), 831-841, 1999
3551999
Hemorrhagic shock induces NAD (P) H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling
J Fan, Y Li, RM Levy, JJ Fan, DJ Hackam, Y Vodovotz, H Yang, KJ Tracey, ...
The Journal of Immunology 178 (10), 6573-6580, 2007
3102007
Necrotizing enterocolitis: new insights into pathogenesis and mechanisms
DF Niņo, CP Sodhi, DJ Hackam
Nature reviews Gastroenterology & hepatology 13 (10), 590-600, 2016
2732016
The role of the intestinal barrier in the pathogenesis of necrotizing enterocolitis
RJ Anand, CL Leaphart, KP Mollen, DJ Hackam
Shock 27 (2), 124-133, 2007
2522007
Host Resistance to Intracellular Infection: Mutation of Natural Resistance-associated Macrophage Protein 1 (Nramp1) Impairs Phagosomal Acidification
DJ Hackam, OD Rotstein, W Zhang, S Gruenheid, P Gros, S Grinstein
The Journal of experimental medicine 188 (2), 351-364, 1998
2441998
Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration
CP Sodhi, C Wohlford-Lenane, Y Yamaguchi, T Prindle, WB Fulton, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (1 …, 2018
2382018
Systemic inflammation and remote organ injury following trauma require HMGB1
RM Levy, KP Mollen, JM Prince, DJ Kaczorowski, R Vallabhaneni, S Liu, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007
2312007
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis
SC Gribar, CP Sodhi, WM Richardson, RJ Anand, GK Gittes, MF Branca, ...
The Journal of Immunology 182 (1), 636-646, 2009
2292009
Mechanism of decreased in vitro murine macrophage cytokine release after exposure to carbon dioxide: relevance to laparoscopic surgery.
MA West, DJ Hackam, J Baker, JL Rodriguez, J Bellingham, OD Rotstein
Annals of surgery 226 (2), 179, 1997
2241997
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice
CP Sodhi, MD Neal, R Siggers, S Sho, C Ma, MF Branca, T Prindle Jr, ...
Gastroenterology 143 (3), 708-718. e5, 2012
2212012
The role of epithelial Toll‐like receptor signaling in the pathogenesis of intestinal inflammation
SC Gribar, RJ Anand, CP Sodhi, DJ Hackam
Journal of leukocyte biology 83 (3), 493-498, 2008
2182008
Rho is required for the initiation of calcium signaling and phagocytosis by Fcγ receptors in macrophages
DJ Hackam, OD Rotstein, A Schreiber, W Zhang, S Grinstein
The Journal of experimental medicine 186 (6), 955-966, 1997
2131997
Toll-like receptor-4 inhibits enterocyte proliferation via impaired β-catenin signaling in necrotizing enterocolitis
CP Sodhi, XH Shi, WM Richardson, ZS Grant, RA Shapiro, T Prindle Jr, ...
Gastroenterology 138 (1), 185-196, 2010
1932010
No longer an innocent bystander: epithelial toll-like receptor signaling in the development of mucosal inflammation
SC Gribar, WM Richardson, CP Sodhi, DJ Hackam
Molecular medicine 14 (9), 645-659, 2008
1922008
Regulation of phagosomal acidification: differential targeting of Na+/H+ exchangers, Na+/K+-ATPases, and vacuolar-type H+-ATPases
DJ Hackam, OD Rotstein, WJ Zhang, N Demaurex, M Woodside, O Tsai, ...
Journal of Biological Chemistry 272 (47), 29810-29820, 1997
1791997
Hypoxia causes an increase in phagocytosis by macrophages in a HIF‐1α‐dependent manner
RJ Anand, SC Gribar, J Li, JW Kohler, MF Branca, T Dubowski, CP Sodhi, ...
Journal of leukocyte biology 82 (5), 1257-1265, 2007
1662007
Disordered enterocyte signaling and intestinal barrier dysfunction in the pathogenesis of necrotizing enterocolitis
DJ Hackam, JS Upperman, A Grishin, HR Ford
Seminars in pediatric surgery 14 (1), 49-57, 2005
1622005
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