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Kenneth D Clevenger
Kenneth D Clevenger
Senior Scientist, AbbVie Inc
Verified email at abbvie.com
Title
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Year
A scalable platform to identify fungal secondary metabolites and their gene clusters
KD Clevenger, JW Bok, R Ye, GP Miley, MH Verdan, T Velk, C Chen, ...
Nature chemical biology 13 (8), 895-901, 2017
1762017
Fungal artificial chromosomes for mining of the fungal secondary metabolome
JW Bok, R Ye, KD Clevenger, D Mead, M Wagner, A Krerowicz, ...
BMC genomics 16, 1-10, 2015
872015
Rational Design of a Transition State Analogue with Picomolar Affinity for Pseudomonas aeruginosa PvdQ, a Siderophore Biosynthetic Enzyme
KD Clevenger, R Wu, JAV Er, D Liu, W Fast
ACS chemical biology 8 (10), 2192-2200, 2013
462013
Identification of the first diketomorpholine biosynthetic pathway using FAC-MS technology
MT Robey, R Ye, JW Bok, KD Clevenger, MN Islam, C Chen, R Gupta, ...
ACS chemical biology 13 (5), 1142-1147, 2018
272018
Removal of magnesium and aluminum impurities from wet process phosphoric acid
KL Parks, KD Clevenger, DP McDonald
US Patent 4,299,804, 1981
231981
Interrogation of benzomalvin biosynthesis using fungal artificial chromosomes with metabolomic scoring (FAC-MS): discovery of a benzodiazepine synthase activity
KD Clevenger, R Ye, JW Bok, PM Thomas, MN Islam, GP Miley, ...
Biochemistry 57 (23), 3237-3243, 2018
212018
Selective targeting by a mechanism-based inactivator against pyridoxal 5′-phosphate-dependent enzymes: Mechanisms of inactivation and alternative turnover
R Mascarenhas, HV Le, KD Clevenger, HJ Lehrer, D Ringe, NL Kelleher, ...
Biochemistry 56 (37), 4951-4961, 2017
202017
Determination of surface coverage and orientation of reduced cytochrome c on a silica surface with polarized ATR spectroscopy
CM Kraning, TL Benz, KS Bloome, GC Campanello, VS Fahrenbach, ...
The Journal of Physical Chemistry C 111 (35), 13062-13067, 2007
192007
n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ
KD Clevenger, R Wu, D Liu, W Fast
Biochemistry 53 (42), 6679-6686, 2014
172014
Substrate trapping in the siderophore tailoring enzyme PvdQ
KD Clevenger, R Mascarenhas, D Catlin, R Wu, NL Kelleher, EJ Drake, ...
ACS chemical biology 12 (3), 643-647, 2017
92017
Neutralization of cooling pond water in phosphoric acid plants
PS O'neill, CW Weston, KD Clevenger, JS Chang
US Patent 4,472,368, 1984
61984
Identification of the first diketomorpholine biosynthetic pathway using FAC-MS technology. ACS Chem Biol 13: 1142–1147
MT Robey, R Ye, JW Bok, KD Clevenger, MN Islam, C Chen, R Gupta, ...
52018
“Clicking” on the lights to reveal bacterial social networking
KD Clevenger, W Fast
ChemBioChem 13 (4), 508-510, 2012
42012
High‐Throughput Natural Products Discovery in Fungi Using FAC‐MS Technology
KD Clevenger, JW Bok, R Ye, GP Miley, MH Verdan, T Velk, C Chen, ...
The FASEB Journal 31, 766.6-766.6, 2017
12017
Systems and methods for untargeted metabolomic screening
NL Kelleher, PM Thomas, KD Clevenger, MT Robey
US Patent App. 17/074,343, 2021
2021
Systems and methods for untargeted metabolomic screening
NL Kelleher, PM Thomas, KD Clevenger, MT Robey
US Patent 10,808,256, 2020
2020
Invited Oral Abstract Presentation Scalable platforms for large scale discovery of microbial natural products
K Clevenger, JW Bok, R Ye, G Miley, M Verdan, T Velk, C Chen, KH Yang, ...
2018
Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover (vol 56, pg 4951, 2017)
R Mascarenhas, HV Le, KD Clevenger, HJ Lehrer, D Ringe, NL Kelleher, ...
BIOCHEMISTRY 56 (43), 5844-5845, 2017
2017
Large scale discovery and deorphanization of natural products using fungal artificial chromosomes and untargeted metabolomics (FAC-MS)
KD Clevenger, JW Bok, R Ye, GP Miley, T Velk, C Chen, K Yang, P Gao, ...
Planta Medica 82 (S 01), SL41, 2016
2016
Reviving natural product and drug discovery pipelines with fungal artificial chromosome (FAC) technology
K Clevenger, JW Bok, R Ye, G Miley, T Velk, C Chen, KH Yang, P Gao, ...
10th Annual TechConnect World Innovation Conference and Expo, Held Jointly …, 2016
2016
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