David T. W. Jones
David T. W. Jones
Group Leader 'Pediatric Glioma Research', DKFZ
Bestätigte E-Mail-Adresse bei dkfz.de
TitelZitiert vonJahr
Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415, 2013
40032013
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226, 2012
13602012
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
10232012
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
DTW Jones, S Kocialkowski, L Liu, DM Pearson, LM Bäcklund, K Ichimura, ...
Cancer research 68 (21), 8673-8677, 2008
6252008
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ...
Acta neuropathologica 123 (4), 473-484, 2012
6172012
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100, 2012
6132012
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
TJ Pugh, SD Weeraratne, TC Archer, DAP Krummel, D Auclair, ...
Nature 488 (7409), 106, 2012
5592012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1-2), 59-71, 2012
5582012
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
K Ichimura, DM Pearson, S Kocialkowski, LM Bäcklund, R Chan, ...
Neuro-oncology 11 (4), 341-347, 2009
5402009
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49, 2012
5372012
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ...
Acta neuropathologica 124 (3), 439-447, 2012
4602012
Medulloblastomics: the end of the beginning
PA Northcott, DTW Jones, M Kool, GW Robinson, RJ Gilbertson, YJ Cho, ...
Nature Reviews Cancer 12 (12), 818, 2012
4362012
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927, 2013
4262013
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ...
Cancer cell 25 (3), 393-405, 2014
3782014
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups
KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ...
Cancer cell 27 (5), 728-743, 2015
3632015
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445, 2014
3512014
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ...
Cancer cell 24 (5), 660-672, 2013
3282013
Paediatric and adult glioblastoma: multiform (epi) genomic culprits emerge
D Sturm, S Bender, DTW Jones, P Lichter, J Grill, O Becher, C Hawkins, ...
Nature Reviews Cancer 14 (2), 92, 2014
3222014
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ...
Cancer cell 20 (2), 143-157, 2011
3132011
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma …
DE Reuss, F Sahm, D Schrimpf, B Wiestler, D Capper, C Koelsche, ...
Acta neuropathologica 129 (1), 133-146, 2015
2832015
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