Rachel J. Perry
Rachel J. Perry
Assistant Professor, Yale University
Verified email at yale.edu - Homepage
Cited by
Cited by
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
RJ Perry, VT Samuel, KF Petersen, GI Shulman
Nature 510 (7503), 84-91, 2014
Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome
RJ Perry, L Peng, NA Barry, GW Cline, D Zhang, RL Cardone, ...
Nature 534 (7606), 213-217, 2016
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes
RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ...
Cell 160 (4), 745-758, 2015
Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
RJ Perry, D Zhang, XM Zhang, JL Boyer, GI Shulman
Science 347 (6227), 1253-1256, 2015
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
RJ Perry, XM Zhang, D Zhang, N Kumashiro, JPG Camporez, GW Cline, ...
Nature medicine 20 (7), 759-763, 2014
Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler
RJ Perry, T Kim, XM Zhang, HY Lee, D Pesta, VB Popov, D Zhang, ...
Cell metabolism 18 (5), 740-748, 2013
N-acylphosphatidylethanolamine, a gut-derived circulating factor induced by fat ingestion, inhibits food intake
MP Gillum, D Zhang, XM Zhang, DM Erion, RA Jamison, C Choi, J Dong, ...
Cell 135 (5), 813-824, 2008
Adolescent obesity and insulin resistance: roles of ectopic fat accumulation and adipose inflammation
S Caprio, R Perry, R Kursawe
Gastroenterology 152 (7), 1638-1646, 2017
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
AK Madiraju, Y Qiu, RJ Perry, Y Rahimi, XM Zhang, D Zhang, ...
Nature medicine 24 (9), 1384-1394, 2018
Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo
T Galbo, RJ Perry, MJ Jurczak, JPG Camporez, TC Alves, M Kahn, ...
Proceedings of the National Academy of Sciences 110 (31), 12780-12785, 2013
Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates type 2 diabetes
K Sharabi, H Lin, CDJ Tavares, JE Dominy, JP Camporez, RJ Perry, ...
Cell 169 (1), 148-160. e15, 2017
FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis
RJ Perry, S Lee, L Ma, D Zhang, J Schlessinger, GI Shulman
Nature communications 6 (1), 1-10, 2015
Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport
A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, ...
Cell reports 21 (4), 1021-1035, 2017
Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13 C magnetic resonance spectroscopy
DE Befroy, RJ Perry, N Jain, S Dufour, GW Cline, JK Trimmer, J Brosnan, ...
Nature medicine 20 (1), 98-102, 2014
Acetyl‐C o A Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents
L Goedeke, J Bates, DF Vatner, RJ Perry, T Wang, R Ramirez, L Li, ...
Hepatology 68 (6), 2197-2211, 2018
Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism
HA Ferris, RJ Perry, GV Moreira, GI Shulman, JD Horton, CR Kahn
Proceedings of the National Academy of Sciences 114 (5), 1189-1194, 2017
Leptin mediates a glucose-fatty acid cycle to maintain glucose homeostasis in starvation
RJ Perry, Y Wang, GW Cline, A Rabin-Court, JD Song, S Dufour, ...
Cell 172 (1-2), 234-248. e17, 2018
Mechanisms by which a very-low-calorie diet reverses hyperglycemia in a rat model of type 2 diabetes
RJ Perry, L Peng, GW Cline, Y Wang, A Rabin-Court, JD Song, D Zhang, ...
Cell metabolism 27 (1), 210-217. e3, 2018
Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance
Y Rahimi, JPG Camporez, MC Petersen, D Pesta, RJ Perry, MJ Jurczak, ...
Proceedings of the National Academy of Sciences 111 (46), 16508-16513, 2014
Propionate increases hepatic pyruvate cycling and anaplerosis and alters mitochondrial metabolism
RJ Perry, CB Borders, GW Cline, XM Zhang, TC Alves, KF Petersen, ...
Journal of Biological Chemistry 291 (23), 12161-12170, 2016
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