Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease AM Hanash, JA Dudakov, G Hua, MH O’Connor, LF Young, NV Singer, ... Immunity 37 (2), 339-350, 2012 | 643 | 2012 |
Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice Y Shono, MD Docampo, JU Peled, SM Perobelli, E Velardi, JJ Tsai, ... Science translational medicine 8 (339), 339ra71-339ra71, 2016 | 505 | 2016 |
Interleukin-22 drives endogenous thymic regeneration in mice JA Dudakov, AM Hanash, RR Jenq, LF Young, A Ghosh, NV Singer, ... Science 336 (6077), 91-95, 2012 | 437 | 2012 |
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia R Rampal, A Alkalin, J Madzo, A Vasanthakumar, E Pronier, J Patel, Y Li, ... Cell reports 9 (5), 1841-1855, 2014 | 305 | 2014 |
Nrf2 regulates haematopoietic stem cell function JJ Tsai, JA Dudakov, K Takahashi, JH Shieh, E Velardi, AM Holland, ... Nature Cell Biology, 2013 | 214 | 2013 |
H3B-6527 is a potent and selective inhibitor of FGFR4 in FGF19-driven hepatocellular carcinoma JJ Joshi, H Coffey, E Corcoran, J Tsai, CL Huang, K Ichikawa, S Prajapati, ... Cancer research 77 (24), 6999-7013, 2017 | 126 | 2017 |
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration T Wertheimer, E Velardi, J Tsai, K Cooper, S Xiao, CC Kloss, KJ Ottmüller, ... Science immunology 3 (19), eaal2736, 2018 | 121 | 2018 |
T cell regeneration after immunological injury E Velardi, JJ Tsai, MRM van den Brink Nature Reviews Immunology 21 (5), 277-291, 2021 | 116 | 2021 |
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling E Velardi, JJ Tsai, AM Holland, T Wertheimer, VWC Yu, JL Zakrzewski, ... Journal of Experimental Medicine 211 (12), 2341-2349, 2014 | 116 | 2014 |
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling E Velardi, JJ Tsai, AM Holland, T Wertheimer, VWC Yu, JL Zakrzewski, ... Journal of Experimental Medicine 211 (12), 2341-2349, 2014 | 116 | 2014 |
Nutritional support from the intestinal microbiota improves hematopoietic reconstitution after bone marrow transplantation in mice A Staffas, MB da Silva, AE Slingerland, A Lazrak, CJ Bare, CD Holman, ... Cell host & microbe 23 (4), 447-457. e4, 2018 | 106 | 2018 |
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease IK Na, SX Lu, NL Yim, GL Goldberg, J Tsai, U Rao, OM Smith, CG King, ... The Journal of clinical investigation 120 (1), 343-356, 2010 | 91 | 2010 |
The central nervous system is a target of acute graft versus host disease in mice S Hartrampf, JA Dudakov, LK Johnson, OM Smith, J Tsai, NV Singer, ... Blood, The Journal of the American Society of Hematology 121 (10), 1906-1910, 2013 | 63 | 2013 |
A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity Y Shono, AZ Tuckett, S Ouk, HC Liou, G Altan-Bonnet, JJ Tsai, JE Oyler, ... Cancer discovery 4 (5), 578-591, 2014 | 58 | 2014 |
Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo IK Na, JC Markley, JJ Tsai, NL Yim, BJ Beattie, AD Klose, AM Holland, ... Blood, The Journal of the American Society of Hematology 116 (11), e18-e25, 2010 | 54 | 2010 |
An intestinal organoid–based platform that recreates susceptibility to T-cell–mediated tissue injury YU Matsuzawa-Ishimoto, A Hine, Y Shono, E Rudensky, A Lazrak, ... Blood, The Journal of the American Society of Hematology 135 (26), 2388-2401, 2020 | 47 | 2020 |
Characterization of a c-Rel inhibitor that mediates anticancer properties in hematologic malignancies by blocking NF-κB–controlled oxidative stress responses Y Shono, AZ Tuckett, HC Liou, E Doubrovina, E Derenzini, S Ouk, JJ Tsai, ... Cancer research 76 (2), 377-389, 2016 | 42 | 2016 |
A chromatin basis for cell lineage and disease risk in the human pancreas HE Arda, J Tsai, YR Rosli, P Giresi, R Bottino, WJ Greenleaf, HY Chang, ... Cell systems 7 (3), 310-322. e4, 2018 | 37 | 2018 |
Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury E Velardi, JJ Tsai, S Radtke, K Cooper, KV Argyropoulos, S Jae-Hung, ... Nature medicine 24 (2), 239-246, 2018 | 35 | 2018 |
Nrf2 regulates CD4+ T cell–induced acute graft-versus-host disease in mice JJ Tsai, E Velardi, Y Shono, KV Argyropoulos, AM Holland, OM Smith, ... Blood, The Journal of the American Society of Hematology 132 (26), 2763-2774, 2018 | 30 | 2018 |