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Jennifer J. Tsai
Jennifer J. Tsai
Bestätigte E-Mail-Adresse bei mskcc.org
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Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
AM Hanash, JA Dudakov, G Hua, MH O’Connor, LF Young, NV Singer, ...
Immunity 37 (2), 339-350, 2012
6432012
Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
Y Shono, MD Docampo, JU Peled, SM Perobelli, E Velardi, JJ Tsai, ...
Science translational medicine 8 (339), 339ra71-339ra71, 2016
5052016
Interleukin-22 drives endogenous thymic regeneration in mice
JA Dudakov, AM Hanash, RR Jenq, LF Young, A Ghosh, NV Singer, ...
Science 336 (6077), 91-95, 2012
4372012
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia
R Rampal, A Alkalin, J Madzo, A Vasanthakumar, E Pronier, J Patel, Y Li, ...
Cell reports 9 (5), 1841-1855, 2014
3052014
Nrf2 regulates haematopoietic stem cell function
JJ Tsai, JA Dudakov, K Takahashi, JH Shieh, E Velardi, AM Holland, ...
Nature Cell Biology, 2013
2142013
H3B-6527 is a potent and selective inhibitor of FGFR4 in FGF19-driven hepatocellular carcinoma
JJ Joshi, H Coffey, E Corcoran, J Tsai, CL Huang, K Ichikawa, S Prajapati, ...
Cancer research 77 (24), 6999-7013, 2017
1262017
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
T Wertheimer, E Velardi, J Tsai, K Cooper, S Xiao, CC Kloss, KJ Ottmüller, ...
Science immunology 3 (19), eaal2736, 2018
1212018
T cell regeneration after immunological injury
E Velardi, JJ Tsai, MRM van den Brink
Nature Reviews Immunology 21 (5), 277-291, 2021
1162021
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling
E Velardi, JJ Tsai, AM Holland, T Wertheimer, VWC Yu, JL Zakrzewski, ...
Journal of Experimental Medicine 211 (12), 2341-2349, 2014
1162014
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling
E Velardi, JJ Tsai, AM Holland, T Wertheimer, VWC Yu, JL Zakrzewski, ...
Journal of Experimental Medicine 211 (12), 2341-2349, 2014
1162014
Nutritional support from the intestinal microbiota improves hematopoietic reconstitution after bone marrow transplantation in mice
A Staffas, MB da Silva, AE Slingerland, A Lazrak, CJ Bare, CD Holman, ...
Cell host & microbe 23 (4), 447-457. e4, 2018
1062018
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease
IK Na, SX Lu, NL Yim, GL Goldberg, J Tsai, U Rao, OM Smith, CG King, ...
The Journal of clinical investigation 120 (1), 343-356, 2010
912010
The central nervous system is a target of acute graft versus host disease in mice
S Hartrampf, JA Dudakov, LK Johnson, OM Smith, J Tsai, NV Singer, ...
Blood, The Journal of the American Society of Hematology 121 (10), 1906-1910, 2013
632013
A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity
Y Shono, AZ Tuckett, S Ouk, HC Liou, G Altan-Bonnet, JJ Tsai, JE Oyler, ...
Cancer discovery 4 (5), 578-591, 2014
582014
Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo
IK Na, JC Markley, JJ Tsai, NL Yim, BJ Beattie, AD Klose, AM Holland, ...
Blood, The Journal of the American Society of Hematology 116 (11), e18-e25, 2010
542010
An intestinal organoid–based platform that recreates susceptibility to T-cell–mediated tissue injury
YU Matsuzawa-Ishimoto, A Hine, Y Shono, E Rudensky, A Lazrak, ...
Blood, The Journal of the American Society of Hematology 135 (26), 2388-2401, 2020
472020
Characterization of a c-Rel inhibitor that mediates anticancer properties in hematologic malignancies by blocking NF-κB–controlled oxidative stress responses
Y Shono, AZ Tuckett, HC Liou, E Doubrovina, E Derenzini, S Ouk, JJ Tsai, ...
Cancer research 76 (2), 377-389, 2016
422016
A chromatin basis for cell lineage and disease risk in the human pancreas
HE Arda, J Tsai, YR Rosli, P Giresi, R Bottino, WJ Greenleaf, HY Chang, ...
Cell systems 7 (3), 310-322. e4, 2018
372018
Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury
E Velardi, JJ Tsai, S Radtke, K Cooper, KV Argyropoulos, S Jae-Hung, ...
Nature medicine 24 (2), 239-246, 2018
352018
Nrf2 regulates CD4+ T cell–induced acute graft-versus-host disease in mice
JJ Tsai, E Velardi, Y Shono, KV Argyropoulos, AM Holland, OM Smith, ...
Blood, The Journal of the American Society of Hematology 132 (26), 2763-2774, 2018
302018
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