Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells DA Lim, YC Huang, T Swigut, AL Mirick, JM Garcia-Verdugo, J Wysocka, ... Nature 458 (7237), 529-533, 2009 | 412 | 2009 |
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors CD Jude, L Climer, D Xu, E Artinger, JK Fisher, P Ernst Cell stem cell 1 (3), 324-337, 2007 | 375 | 2007 |
Mammalian Trithorax and Polycomb-group homologues are antagonistic regulators of homeotic development RD Hanson, JL Hess, BD Yu, P Ernst, M Van Lohuizen, A Berns, ... Proceedings of the National Academy of Sciences 96 (25), 14372-14377, 1999 | 334 | 1999 |
Definitive hematopoiesis requires the mixed-lineage leukemia gene P Ernst, JK Fisher, W Avery, S Wade, D Foy, SJ Korsmeyer Developmental cell 6 (3), 437-443, 2004 | 321 | 2004 |
MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein P Ernst, J Wang, M Huang, RH Goodman, SJ Korsmeyer Molecular and cellular biology 21 (7), 2249-2258, 2001 | 314 | 2001 |
Proteolytic cleavage of MLL generates a complex of N-and C-terminal fragments that confers protein stability and subnuclear localization JJD Hsieh, P Ernst, H Erdjument-Bromage, P Tempst, SJ Korsmeyer Molecular and cellular biology 23 (1), 186-194, 2003 | 296 | 2003 |
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene K Hahm, P Ernst, K Lo, GS Kim, C Turck, ST Smale Molecular and cellular biology, 1994 | 296 | 1994 |
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes AJ Davidson, P Ernst, Y Wang, MPS Dekens, PD Kingsley, J Palis, ... Nature 425 (6955), 300-306, 2003 | 290 | 2003 |
MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele AT Thiel, P Blessington, T Zou, D Feather, X Wu, J Yan, H Zhang, Z Liu, ... Cancer cell 17 (2), 148-159, 2010 | 269 | 2010 |
Embryonic stem cell-derived hematopoietic stem cells Y Wang, F Yates, O Naveiras, P Ernst, GQ Daley Proceedings of the National Academy of Sciences 102 (52), 19081-19086, 2005 | 255 | 2005 |
An Mll-dependent Hox program drives hematopoietic progenitor expansion P Ernst, M Mabon, AJ Davidson, LI Zon, SJ Korsmeyer Current Biology 14 (22), 2063-2069, 2004 | 245 | 2004 |
The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition RV Stan, D Tse, SJ Deharvengt, NC Smits, Y Xu, MR Luciano, ... Developmental cell 23 (6), 1203-1218, 2012 | 210 | 2012 |
The role of MLL in hematopoiesis and leukemia P Ernst, J Wang, SJ Korsmeyer Current opinion in hematology 9 (4), 282-287, 2002 | 202 | 2002 |
Down-regulation of TDT transcription in CD4+ CD8+ thymocytes by Ikaros proteins in direct competition with an Ets activator LA Trinh, R Ferrini, BS Cobb, AS Weinmann, K Hahm, P Ernst, ... Genes & development 15 (14), 1817-1832, 2001 | 177 | 2001 |
WRAD: enabler of the SET1-family of H3K4 methyltransferases P Ernst, CR Vakoc Briefings in functional genomics 11 (3), 217-226, 2012 | 152 | 2012 |
The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis BP Mishra, KM Zaffuto, EL Artinger, T Org, HKA Mikkola, C Cheng, ... Cell reports 7 (4), 1239-1247, 2014 | 151 | 2014 |
Combinatorial regulation of transcription II: the immunoglobulin μ heavy chain gene P Ernst, ST Smale Immunity 2 (5), 427-438, 1995 | 144 | 1995 |
Conditional MLL‐CBP targets GMP and models therapy‐related myeloproliferative disease J Wang, H Iwasaki, A Krivtsov, PG Febbo, AR Thorner, P Ernst, ... The EMBO journal 24 (2), 368-381, 2005 | 142 | 2005 |
Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory M Jakovcevski, H Ruan, EY Shen, A Dincer, B Javidfar, Q Ma, CJ Peter, ... Journal of Neuroscience 35 (13), 5097-5108, 2015 | 140 | 2015 |
Combinatorial regulation of transcription I: general aspects of transcriptional control P Ernst, ST Smale Immunity 2 (4), 311-319, 1995 | 130 | 1995 |