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Prarthana Mohanraju
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Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ...
Nature biotechnology 35 (1), 31-34, 2017
9212017
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
P Mohanraju, KS Makarova, B Zetsche, F Zhang, EV Koonin, ...
Science 353 (6299), aad5147, 2016
6942016
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
VJ Carrión, J Perez-Jaramillo, V Cordovez, V Tracanna, M De Hollander, ...
Science 366 (6465), 606-612, 2019
6632019
Characterizing a thermostable Cas9 for bacterial genome editing and silencing
I Mougiakos, P Mohanraju, EF Bosma, V Vrouwe, M Finger Bou, ...
Nature communications 8 (1), 1647, 2017
1432017
CRISPR–Cas ribonucleoprotein mediated homology-directed repair for efficient targeted genome editing in microalgae Nannochloropsis oceanica IMET1
MIS Naduthodi, P Mohanraju, C Südfeld, S D’Adamo, MJ Barbosa, ...
Biotechnology for biofuels 12, 1-11, 2019
812019
Keeping crispr in check: diverse mechanisms of phage-encoded anti-crisprs
D Trasanidou, AS Geros, P Mohanraju, AC Nieuwenweg, FL Nobrega, ...
FEMS microbiology letters 366 (9), fnz098, 2019
792019
Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a
SCA Creutzburg, WY Wu, P Mohanraju, T Swartjes, F Alkan, J Gorodkin, ...
Nucleic acids research 48 (6), 3228-3243, 2020
682020
Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR–Cas effector complexes
M Vlot, J Houkes, SJA Lochs, DC Swarts, P Zheng, T Kunne, P Mohanraju, ...
Nucleic acids research 46 (2), 873-885, 2018
642018
Alternative functions of CRISPR–Cas systems in the evolutionary arms race
P Mohanraju, C Saha, P van Baarlen, R Louwen, RHJ Staals, ...
Nature Reviews Microbiology 20 (6), 351-364, 2022
452022
Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA
C Saha, P Mohanraju, A Stubbs, G Dugar, Y Hoogstrate, GJ Kremers, ...
Science advances 6 (25), eaaz4849, 2020
392020
Prime editing: advances and therapeutic applications
Z Zhao, P Shang, P Mohanraju, N Geijsen
Trends in Biotechnology 41 (8), 1000-1012, 2023
352023
Heterologous expression and purification of the CRISPR-Cas12a/Cpf1 protein
P Mohanraju, J Van Der Oost, M Jinek, DC Swarts
Bio-protocol 8 (9), e2842-e2842, 2018
302018
The miniature CRISPR-Cas12m effector binds DNA to block transcription
WY Wu, P Mohanraju, C Liao, B Adiego-Pérez, SCA Creutzburg, ...
Molecular Cell 82 (23), 4487-4502. e7, 2022
272022
Development of a Cas12a-based genome editing tool for moderate thermophiles
P Mohanraju, I Mougiakos, J Albers, M Mabuchi, RT Fuchs, JL Curcuru, ...
The CRISPR Journal 4 (1), 82-91, 2021
92021
Thermostable Cas9 nucleases
J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju
US Patent 11,326,162, 2022
22022
Thermostable cas9 nucleases
J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju
US Patent App. 16/469,691, 2019
12019
Characterization of the AcrIIC1 anti‒CRISPR protein for Cas9‒based genome engineering in E. coli
D Trasanidou, A Potocnik, P Barendse, P Mohanraju, E Bouzetos, ...
Communications Biology 6 (1), 1042, 2023
2023
Crispr type v-u1 system from mycobacterium mucogenicum and uses thereof
J Van Der Oost, P Mohanraju, WY Wu, S Creutzburg
US Patent App. 17/624,439, 2022
2022
Thermostable cas9 nucleases
J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju
US Patent App. 17/575,952, 2022
2022
Thermostable cas9 nucleases
J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju
US Patent App. 16/469,683, 2019
2019
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