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Gurol Tuncman, MD, Ph.D.
Gurol Tuncman, MD, Ph.D.
Sabri Ülker Center, Harvard TH Chan School of Public Health
Verified email at hsph.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Ozcan, Q Cao, E Yilmaz, AH Lee, NN Iwakoshi, E Ozdelen, G Tuncman, ...
Science 306 (5695), 457-461, 2004
45512004
A central role for JNK in obesity and insulin resistance
J Hirosumi, G Tuncman, L Chang, CZ Görgün, KT Uysal, K Maeda, ...
Nature 420 (6913), 333-336, 2002
41592002
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
M Furuhashi, G Tuncman, CZ Görgün, L Makowski, G Atsumi, ...
Nature 447 (7147), 959-965, 2007
8532007
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis
T Nakamura, M Furuhashi, P Li, H Cao, G Tuncman, N Sonenberg, ...
Cell 140 (3), 338-348, 2010
5862010
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
G Tuncman, J Hirosumi, G Solinas, L Chang, M Karin, GS Hotamisligil
Proceedings of the National Academy of Sciences 103 (28), 10741-10746, 2006
4502006
Adipocyte/macrophage fatty acid–binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice
M Furuhashi, R Fucho, CZ Görgün, G Tuncman, H Cao, GS Hotamisligil
The Journal of clinical investigation 118 (7), 2640-2650, 2008
3842008
A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease
G Tuncman, E Erbay, X Hom, I De Vivo, H Campos, EB Rimm, ...
Proceedings of the National Academy of Sciences 103 (18), 6970-6975, 2006
3512006
Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production
H Cao, M Sekiya, ME Ertunc, MF Burak, JR Mayers, A White, K Inouye, ...
Cell metabolism 17 (5), 768-778, 2013
2612013
The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans
A Tirosh, ES Calay, G Tuncman, KC Claiborn, KE Inouye, K Eguchi, ...
Science translational medicine 11 (489), eaav0120, 2019
2232019
Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes
MF Burak, KE Inouye, A White, A Lee, G Tuncman, ES Calay, M Sekiya, ...
Science translational medicine 7 (319), 319ra205-319ra205, 2015
942015
Intercellular transmission of hepatic ER stress in obesity disrupts systemic metabolism
A Tirosh, G Tuncman, ES Calay, M Rathaus, I Ron, A Tirosh, A Yalcin, ...
Cell Metabolism 33 (2), 319-333. e6, 2021
602021
Divergent roles for p55 and p75 TNF-α receptors in the induction of plasminogen activator inhibitor-1
M Pandey, G Tuncman, GS Hotamisligil, F Samad
The American journal of pathology 162 (3), 933-941, 2003
572003
Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia
S Peller, R Yona, Y Kopilova, M Prokocimer, N Goldfinger, A Uysal, ...
Genes, Chromosomes and Cancer 21 (1), 2-7, 1998
291998
Null alleles of the aldolase B gene in patients with hereditary fructose intolerance.
M Ali, G Tuncman, NC Cross, M Vidailhet, I Bökesoy, R Gitzelmann, ...
Journal of medical genetics 31 (6), 499-503, 1994
211994
948 Gorgun C, Glimcher LH, and Hotamisligil GS
U Ozcan, Q Cao, E Yilmaz, AH Lee, NN Iwakoshi, E Ozdelen, G Tuncman
Endoplasmic reticulum stress links 949, 457-461, 0
9
OR01-1: Leveraging Immunometabolic Control to Prevent and Treat Obesity Related Asthma
MF Burak, N Dagtekin, P Bejo, E Vaillancourt, L Liu, C Gorgun, E Rimm, ...
Journal of the Endocrine Society 3 (Supplement_1), OR01-1, 2019
12019
FABP4 as a Therapeutic Host Target Controlling SARS-CoV2 Infection
H Baazim, E Koyuncu, G Tuncman, MF Burak, L Merkel, N Bahour, ...
bioRxiv, 2024.02. 10.579717, 2024
2024
COMPOUNDS USEFUL TO TREAT METABOLIC DISORDERS
GS Hotamisligil, E Calay, A Tirosh, G Tuncman, M Sekiya
US Patent App. 16/937,316, 2021
2021
Compounds useful to treat metabolic disorders
GS Hotamisligil, E Calay, A Tirosh, G Tuncman, M Sekiya
US Patent App. 16/228,297, 2019
2019
The Effects of the Common Food Preservative Propionic Acid on Postprandial Metabolism and Body Weight
A Tirosh, ES Calay, G Tuncman, KC Claiborn, K Eguchi, M Rathaus, I Ron, ...
DIABETES 66, A522-A522, 2017
2017
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