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Christopher C. Mader
Christopher C. Mader
Flatiron Health
Bestätigte E-Mail-Adresse bei flatiron.com
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Zitiert von
Jahr
The Drug Repurposing Hub: a next-generation drug library and information resource
SM Corsello, JA Bittker, Z Liu, J Gould, P McCarren, JE Hirschman, ...
Nature medicine 23 (4), 405-408, 2017
8042017
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
Nature cancer 1 (2), 235-248, 2020
5092020
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
M Oser, H Yamaguchi, CC Mader, JJ Bravo-Cordero, M Arias, X Chen, ...
Journal of Cell Biology 186 (4), 571-587, 2009
4372009
An EGFR–Src–Arg–cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion
CC Mader, M Oser, MAO Magalhaes, JJ Bravo-Cordero, J Condeelis, ...
Cancer research 71 (5), 1730-1741, 2011
3402011
Immunomodulatory spherical nucleic acids
AF Radovic-Moreno, N Chernyak, CC Mader, S Nallagatla, RS Kang, ...
Proceedings of the National Academy of Sciences 112 (13), 3892-3897, 2015
2792015
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
GS Kinker, AC Greenwald, R Tal, Z Orlova, MS Cuoco, JM McFarland, ...
Nature genetics 52 (11), 1208-1218, 2020
2602020
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway
MAO Magalhaes, DR Larson, CC Mader, JJ Bravo-Cordero, H Gil-Henn, ...
Journal of Cell Biology 195 (5), 903-920, 2011
2462011
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia
M Oser, CC Mader, H Gil-Henn, M Magalhaes, JJ Bravo-Cordero, ...
Journal of cell science 123 (21), 3662-3673, 2010
1892010
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ...
Nucleic acids research 46 (D1), D558-D566, 2018
1682018
The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
C Chung, CC Mader, JC Schmitz, J Atladottir, P Fitchev, ML Cornwell, ...
Laboratory investigation 91 (5), 732-743, 2011
1372011
Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion
S Lapetina, CC Mader, K Machida, BJ Mayer, AJ Koleske
Journal of cell biology 185 (3), 503-519, 2009
1202009
Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate
LR Giam, MD Massich, L Hao, L Shin Wong, CC Mader, CA Mirkin
Proceedings of the National Academy of Sciences 109 (12), 4377-4382, 2012
1102012
Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells
BJ Rosenberg, H Gil-Henn, CC Mader, T Halo, T Yin, J Condeelis, ...
Molecular biology of the cell 28 (10), 1347-1360, 2017
472017
Lessons learned from SARS-CoV-2 measurements in wastewater
ME Sharkey, N Kumar, AMA Mantero, KM Babler, MM Boone, ...
Science of The Total Environment 798, 149177, 2021
412021
Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes
JE Hornick, CC Mader, EK Tribble, CC Bagne, KT Vaughan, SL Shaw, ...
Current biology 21 (7), 598-605, 2011
412011
Non-oncology drugs are a source of previously unappreciated anti-cancer activity
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
BioRxiv, 730119, 2019
352019
Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
AF Radovic-Moreno, CC Mader, S Nallagatla, W Hasan, A Love, ...
US Patent 10,894,963, 2021
332021
Liposomal particles, methods of making same and uses thereof
CA Mirkin, ST Nguyen, RS Banga, N Chernyak, S Gryaznov, ...
US Patent 10,182,988, 2019
242019
Spherical nucleic acid-based constructs as immunoregulatory agents
S Gryaznov, CC Mader, AF Radovic-Moreno
232015
Probing cell shape regulation with patterned substratum: requirement of myosin II-mediated contractility
CC Mader, EH Hinchcliffe, Y Wang
Soft Matter 3 (3), 357-363, 2007
202007
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